A5103227767- Traditional Chinese Medicine Analysis
- Chromatography in Natural Products
- Phytochemical Studies and Bioactivities
- Natural product bioactivities and synthesis
- Traditional Chinese Medicine Studies
- Metabolomics and Mass Spectrometry Studies
- Phytochemistry and Biological Activities
- Plant-based Medicinal Research
- Wireless Power Transfer Systems
- Energy Harvesting in Wireless Networks
- Phytochemicals and Antioxidant Activities
- Pharmacological Effects of Natural Compounds
- Ginseng Biological Effects and Applications
- Phytochemistry and Bioactive Compounds
- Natural Products and Biological Research
- Wireless Body Area Networks
- Synthesis and biological activity
- Genomics, phytochemicals, and oxidative stress
- Herbal Medicine Research Studies
- Graphene research and applications
- Polysaccharides and Plant Cell Walls
- Phytochemistry and biological activities of Ficus species
- Drug Transport and Resistance Mechanisms
- Soil, Finite Element Methods
- Cell death mechanisms and regulation
Sichuan Academy of Traditional Chinese Medicine
2017-2022
Hong Kong Baptist University
2012-2017
Shanghai Jiao Tong University
2011-2012
Tongji University
2001-2005
Inductive coupling is commonly used for wireless power and data transfer in biomedical telemetry systems. To increase bandwidth while maintaining efficiency, a multiband system transmitting using different frequencies has been adopted. However, the link interact with each other, complicating operation of both transmission. In this paper, we demonstrate that to achieve high performance transmission, cross-coupling between coils have be taken into consideration. Design equations derived shown...
Gastric cancer remains a major health problem worldwide. Natural products, with stronger antitumor activity and fewer side effects, are potential candidates for pharmaceutical development as anticancer agents. In this study, quercetin curcumin were chosen testing applied separately in combination to human gastric MGC-803 cells. The MTT assay was used evaluate cell growth inhibition. Annexin V-FITC/PI carried out measure apoptosis rate. Flow cytometry performed analyze mitochondrial membrane...
Dioscorea is a genus of flowering plants, and some species are known used as source for the steroidal sapogenin diosgenin. To screen potential resource from related medicinal plants diosgenin extraction, rapid method to compare contents in various crucial. An ultra-performance liquid chromatography (UPLC) coupled with diode array detection (DAD) electrospray ionization mass spectrometry (ESI-MS) was developed identification determination plants. A comprehensive validation conducted....
Root of Ficus hirta (RFH) is widely consumed in China as a plant-derived popular food. However, contents the active constituents RFH are unknown, and chemical well bioactive properties may be affected by growing area. In order to ensure standard efficacy health products made with RFH, its should firstly determined and, secondly, means assessing samples for their these needed.Four components, including two coumarins, namely psoralen bergapten, flavonoids, luteolin apigenin, twenty were...
Herbal healthcare products are used worldwide as relatively safe and effective alternatives to allopathic drugs. Saussurea laniceps Hand.‐Mazz. (SL), S . medusa Maxim. (SM) involucrata (Kar. et Kir.) Sch.Bip. (SI) three sources of the renowned 'snow lotus', Chinese materia medica for treating inflammatory diseases. The species have different therapeutic effects, among which SL has been proved be most potent, but they frequently confused on market in academic community. An ultra‐high...
"Dragon's Blood" (DB) has long been used as an ethnomedicine in China to invigorate blood circulation for the treatment of traumatic injuries, stasis and pain. To comprehensively assess quality DB medicine, a precise accurate method that can rapidly separate, characterize quantify multiple active components is crucial.An ultra performance liquid chromatography (UPLC) coupled with photodiode array detection (PAD) electrospray ionization mass spectrometry (ESI-MS) was developed...
ABSTRACT Introduction Dioscorea nipponica (DN) and D. panthaica (DP) have been uniquely prepared as herbal medicinal products for treating coronary heart disease (CHD) in China. However, so far there has little discussion no work comparing the qualitative quantitative differences between two herbs nor assessing whether they similarities chemical composition that would support their common application CHD. Objective To develop an efficient reliable method based on UPLC–qTOF–MS comparison of...
Rhizoma Chuanxiong (RC) is the dried rhizome of Ligusticum chuanxiong Hort., and various types processed (PRC) are widely used in China. However, quality assurance control these medicines remain challenging. This study aims to investigate chemical compositions PRC preparations by a high-performance liquid chromatography (HPLC) coupled with diode array detection (DAD) method.A HPLC-DAD method validation was developed for samples. Seven batches plant samples from two processing methods,...
Rhizoma Chuanxiong (RC; Chuanxiong), which is the dried rhizome of Ligusticum chuanxiong (Umbelliferae), commonly used in Chinese medicine (CM) for improving blood circulation and dispersing stasis. RC usually processed before use clinical practice to enhance its therapeutic efficacy. This study aimed investigate temporal variations major constituents by HPLC-DAD-MS during herbal processing effects an adjuvant (e.g., wine), steaming vs stir-frying optimal time. An method was developed...
Studying the biotransformation of natural products by intestinal microflora is an important approach to understanding how and why some medicines-particularly medicines-work. In many cases, active components are generated metabolic activation. This critical for drug research development. As a means explore therapeutic mechanism Dioscorea nipponica (DN), medicinal plant used treat myocardial ischemia (MI), metabolites from DN were identified, cardioprotective efficacy these was evaluated. Our...
In this article, reversal activities of Euphorbia factor L1 (EFL1) against ABCB1-mediated multidrug resistance (MDR) and apoptosis sensitization in K562/ADR cells are reported. EFL1 decreased the IC50 values anticancer agents over-expressing ABCB1. However, did not affect sensitive K562 cells. Additionally, increased intracellular accumulation rhodamine 123 doxorubicin without affecting their Furthermore, sensitized triggered by vincristine via mitochondrial pathway, as confirmed Annexin...
"Snow lotus" is a famous Chinese Materia Medica derived from species of the genus Saussurea (Compositae). To differentiate three representative easily-confused snow lotus herbs, namely, involucrata (Kar. et Kir.) Sch.-Bip, laniceps Hand.-Mazz., and medusa Maxim., macroscopic features herbs were systemically observed, microscopic compared by using ordinary light microscopy, polarized microscopy scanning electron (SEM). The results indicate that, as for identification, capitula situation...
Abstract This paper reports a novel strategy based on high-speed counter-current chromatography (HSCCC) technique to separate in vivo metabolites from refined extract of urine after administration an herbal medicine. Saussurea laniceps (SL) was chosen as model medicine be used test the feasibility our proposed strategy. succeeded case separating four SL rats. Briefly, oral three rats for ten days (2.0 g/kg/d), 269.1 mg umbelliferone glucuronide ( M1 , purity, 92.5%), 432.5 scopoletin M2...
ABSTRACT Confusion in the species associated with name of “Bixie” Chinese Materia Medica began centuries ago. In recent decades, diverse medicinal plants from genera Dioscorea and Smilax , even minor genus Heterosmilax have been documented under Bixie or a very similar as folk medicines different areas China. However, traditional efficacies chemical profiles these herbs are not exactly same vary wildly. Comprehensive authentication multiple has yet attempted. To differentiate ensure correct...
Danggui Buxue Tang (DBT) is a Traditional Chinese Medicine (TCM) formula primarily used to treat symptoms associated with menopause in women. Usually, DBT composed of one portion Radix Angelicae Sinensis (RAS) and five portions Astragali (RA). Clinically, Hedysari (RH) sometimes by TCM physicians replace RA DBT. In order verity whether the chemical constituents DBT1 (RA:RAS = 5:1, w/w) DBT2 (RH:RAS share similarities profiles two DBTs crude extracts urine samples were analyzed compared aid...
The quality of the materials used in Chinese medicine (CM) is generally assessed based on an analysis their chemical components (e.g., chromatographic fingerprint analysis). However, there a growing interest use color metrics as indicator CM. aim this study was to investigate accuracy and feasibility using determine Smilacis Glabrae Rhizoma (Tufuling) (SGR). SGR samples were divided into two categories cross-sectional coloration, including red (R-SGR) white (W-SGR). Forty-three collected...
Amino alcohol alkaloids are the active components in lateral root of Aconitum carmichaelii Debx. (Fuzi), and they have a variety pharmacological activities. However, chemical fingerprints ester reported to date were mainly obtained from high-performance liquid chromatography coupled with ultraviolet detection, it is difficult obtain information about amino Fuzi such chromatograms. In this paper, comprehensive fingerprinting method was established using an evaporative light-scattering...
The root of Fordia cauliflora Hemsl (FC) has long been used in southern China for the treatment rheumatism, bruises, dementia children, and valetudinarianism. However, sometimes it is mixed with other parts. And always confused Millettia pulchra (Benth.) Kurz var. laxior (Dunn) Z. Wei (MP) by local people. chemical differences between two ethnic drugs are not clear until now. aim this study to develop a precise accurate method characterize quantify multiple components FC, which helpful...