Masaki Ishida

ORCID: 0000-0003-1501-0343
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About
Contact & Profiles
Research Areas
  • Enzyme function and inhibition
  • Metalloenzymes and iron-sulfur proteins
  • Metal-Catalyzed Oxygenation Mechanisms

High Energy Accelerator Research Organization
2021

Carbonic anhydrases (CAs) are universal metalloenzymes that catalyze the reversible conversion of carbon dioxide (CO2) and bicarbonate (HCO3-). They involved in various biological processes, including pH control, respiration, photosynthesis. To date, eight evolutionarily unrelated classes CA families (α, β, γ, δ, ζ, η, θ, ι) have been identified. All characterized by an active site accommodating binding a metal cofactor, which is assumed to play central role catalysis. This feature thought...

10.1186/s12915-021-01039-8 article EN cc-by BMC Biology 2021-05-18
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