A5068877365- Malaria Research and Control
- Research on Leishmaniasis Studies
- Mosquito-borne diseases and control
- Insect Resistance and Genetics
- Insect Pest Control Strategies
- Trypanosoma species research and implications
- Parasites and Host Interactions
- Date Palm Research Studies
- Identification and Quantification in Food
- Yersinia bacterium, plague, ectoparasites research
- Dengue and Mosquito Control Research
- Vibrio bacteria research studies
- Insect symbiosis and bacterial influences
- Viral Infections and Vectors
- Animal Disease Management and Epidemiology
- Ethnobotanical and Medicinal Plants Studies
- SARS-CoV-2 detection and testing
- COVID-19 Clinical Research Studies
- Leptospirosis research and findings
- Agricultural pest management studies
- Blood donation and transfusion practices
- Vector-borne infectious diseases
- Livestock and Poultry Management
- SARS-CoV-2 and COVID-19 Research
Jigjiga University
2016-2025
Swiss Tropical and Public Health Institute
2024
Addis Ababa University
2014-2020
University of Georgia
2019-2020
University of North Carolina at Charlotte
2019-2020
Baylor University
2019-2020
Malaria is a major public health concern in Ethiopia. With the increase malaria cases Somali Region of Ethiopia, understanding distribution and identifying species vectors vital to health. Here we report first detection Anopheles stephensi vector typically found Middle East, Indian subcontinent, China, but recently Djibouti. An entomological investigation was conducted during November December 2016 Kebri Dehar town Ethiopian Regional State as ancillary work for spp. surveillance. Mosquito...
The recent detection of the South Asian malaria vector Anopheles stephensi in Ethiopia and other regions Horn Africa has raised concerns about its potential impact on transmission. We report here findings a survey for this species eastern using both morphological molecular methods identification.Adult larval/pupal collections were conducted at ten sites specimens identified standard keys genetic analysis.In total, 2231 morphologically An. collected. A approach incorporating PCR endpoint...
Abstract Background Anopheles stephensi , an invasive malaria vector, was first detected in Africa nearly 10 years ago. After the initial finding Djibouti, it has subsequently been found Ethiopia, Sudan and Somalia. To better inform policies vector control decisions, is important to understand distribution, bionomics, insecticide susceptibility, transmission potential of An. . These aspects were studied as part routine entomological monitoring Ethiopia between 2018 2020. Methods Adult...
Abstract Background The movement of malaria vectors into new areas is a growing concern in the efforts to control malaria. recent report Anopheles stephensi eastern Ethiopia has raised necessity understand insecticide resistance status vector region better inform vector-based interventions. aim this study was evaluate An. using two approaches: (1) World Health Organization (WHO) bioassay tests stephensi; and (2) genetic analysis genes Ethiopia. Methods Mosquito larvae pupae were collected...
Visceral leishmaniasis (VL, also called "kala-azar"), is a life threatening neglected tropical infectious disease which mainly affects the poorest of poor. VL prevalent in Ethiopia particularly northwest country. Understanding risk factors infection helps its prevention and control. The aim present study was to identify associated with VL. A case–control carried out during period January-July 2013 Ethiopia. Cases controls were diagnosed using clinical presentation, rk39 rapid diagnostic test...
Abstract Background The recent detection of the South Asian malaria vector Anopheles stephensi in Horn Africa (HOA) raises concerns about impact this mosquito on transmission region. Analysis An. genetic diversity and population structure can provide insight into history HOA to improve predictions future spread. We investigated eastern Ethiopia, where suggests a range expansion region, order understand invasive population. Methods sequenced cytochrome oxidase subunit I ( COI ) B gene CytB...
Anopheles stephensi invasion in the Horn of Africa (HoA) poses a substantial risk increased malaria disease burden region. An understanding history introduction(s), establishment(s) and potential A. sources HoA is needed to predict future expansions establish where they may be effectively controlled. To this end, we take landscape genomic approach assess origins spread throughout HoA, information essential for vector control. Specifically, assayed 2070 genome-wide single nucleotide...
Introduction Arboviral diseases, such as dengue, chikungunya, yellow fever, and Zika, are caused by viruses that transmitted to humans through mosquito bites. However, the status of arbovirus vectors in eastern Ethiopia is unknown. The aim this study was investigate distribution, breeding habitat, bionomics phylogenetic relationship Aedes aegypti species Somali Regional State, Eastern Ethiopia. Methods Entomological surveys were conducted four sites including Jigjiga, Degehabur, Kebridehar...
Blood-feeding behavior studies are important for estimating the efficiency of pathogen transmission and assessing relative human disease risk. However, in Ethiopia other parts East Africa there large remaining gaps identifying feeding habits Phlebotomus orientalis, vector Leishmania donovani. The aim study was to determine blood patterns P. orientalis Tahtay Adiyabo district, northern Ethiopia.For bloodmeal analysis, sandflies were collected from three different villages district using CDC...
The recent finding of a typically non-African Anopheles species in eastern Ethiopia emphasizes the need for detailed identification and characterization effective malaria vector surveillance. Molecular approaches increase accuracy interoperability surveillance data. To develop molecular assays identification, it is important to evaluate different genetic loci ability characterize population level variation. Here utility internal transcribed spacer 2 (ITS2) cytochrome oxidase I (COI)...
Abstract Background Ethiopia has shown notable progress in reducing the burden of malaria over past two decades. Because this progress, country shifted efforts from control to elimination malaria. This study was conducted analyse epidemiology and stratification incidence setting eastern Ethiopia. Methods A retrospective by reviewing district health office data 2013 2019 Harari Region. In addition, three years sub-district level were used stratify transmission intensity. Malaria interventions...
Visceral leishmaniasis (VL) is a neglected tropical disease, which strongly associated with poverty. VL caused by Leishmania donovani and transmitted Phlebotomus orientalis endemic in various remote areas of north north-west Ethiopia. The present study was designed to determine the sand fly fauna bionomics P. focus Tahtay Adiyabo district.Sand flies were collected using CDC light traps (n = 602), sticky 9,350) indoor pyrethrum spray catches 578 house visits) from indoor, peri-domestic...
Visceral leishmaniasis (VL) or kala-azar cases in seasonal labour migrants from highland areas are addressed to travel history the Metema-Humera lowlands, northwestern Ethiopia. Factors that affect incidence of VL extra-domestic habitats were not evaluated. The aim this study was evaluate sero-prevalence Leishmania donovani infection randomly selected migrant workers and entomological risk factors which might kala-azar.Sero-prevalence L. obtained Direct Agglutination Test (DAT) using blood...
Visceral leishmaniasis (VL, or "kala-azar") is a major cause of disability and death, especially in East Africa. Its vectors, sand flies (Diptera: Psychodidae: Phlebotominae), are poorly controlled guarded against these regions, owing part to lack understanding about their feeding behavior.A total 746 freshly fed female were collected five population centers Kafta Humera (northwestern Ethiopia), where VL endemic. Flies from habitats that ranged inside houses open fields, using light traps...
The invasion of Africa by Anopheles stephensi poses a significant threat to malaria elimination. As An. exploits wide array urban artificial larval habitats, it may be less impacted rainfall variability compared other native species. We empirically investigated this assumption quantifying the seasonal transition an established population from eastern Ethiopia between rainy and dry periods. Monthly surveys generated evidence heterogeneity seasons in type habitat their productivity. season...
Despite previous decline of malaria in Ethiopia, an outbreak Dire Dawa 2022 implicated invasive vector An. stephensi as responsible. The transmission Plasmodium by raises questions about the molecular basis compatibility, and origin being transmitted. P47 gene is a parasite-vector interaction Anopheles , along with corresponding mosquito receptor ( P47Rec ), can be critical establishment infections anophelines. Here, we analyzed sequences to determine detected during evaluate markers...
The Leishmaniases are caused by the protozoan parasites of genus Leishmania and transmitted to humans bite infected female phlebotomine sand flies. Both visceral cutaneous leishmaniases widely distributed in different parts Ethiopia. aim this study was determine diversity altitudinal distribution flies from Kafta Humera Gondar town northwest Ethiopia.Seven localities were selected with distinct variations between 550m above sea level (m a.s.l) 2300m a.s.l. In each locality, collected using...
Host choice and feeding success of sand fly vectors visceral leishmaniasis (VL) are important factors in understanding the epidemiology for developing efficient control strategies. The aim present study was to determine host preference Phlebotomus orientalis VL focus Tahtay Adiyabo district, northern Ethiopia. Two separate experiments were conducted testing attraction P. humans, domestic animals, small wild animals. other species assessed using tent traps baited with seven different animals...
Phlebotomus orientalis is the major vector of intramacrophage protozoa, Leishmania donovani, etiological agent visceral leishmaniasis (VL) in northern Ethiopia and Sudan. The objective this study was to determine nocturnal periodicity P. VL endemic focus Tahtay Adiyabo district, Ethiopia.
Visceral leishmaniasis (VL) also known as kala-azar is a growing health problem in Ethiopia with an estimated annual VL incidence between 3700 and 7400. The disease mainly endemic northwestern parts of the country. aim current study was to determine sand fly fauna ecology Phlebotomus orientalis two ecologically distinct areas Ethiopia.Sand flies were collected using CDC light traps, sticky traps pyrethrum spray catches from peri-domestic, mixed forest, farm field indoor habitats both...
Anopheles stephensi is a malaria vector that has been recently introduced into East Africa, where it threatens to increase disease burden. The use of insecticides, especially pyrethroids, still one the primary control strategies worldwide. knockdown resistance (kdr) mutation in IIS6 transmembrane segment voltage-gated sodium channel (vgsc) main molecular mechanisms pyrethroid Anopheles. Extensive An. previously reported Ethiopia. Thus, important determine whether or not kdr present...
Phlebotomus orientalis is the main sandfly vector of visceral leishmaniasis in north and northwest Ethiopia. CDC light traps sticky are commonly used for monitoring populations. However, their trapping efficiency greatly influenced by various environmental factors including moonlight lunar periodicity. In view that, current study assessed effect periodicity on performance collecting P. orientalis. Trapping other spp. was conducted 7 months between December 2012 June 2013 using from...
The malaria vector, Anopheles stephensi, which is typically restricted to South Asia and the Middle East, was recently detected in Horn of Africa. Addressing spread this vector could involve integrated control that considers status insecticide resistance multiple species region. Previous reports indicate knockdown mutations (kdr) voltage-gated sodium channel (vgsc) are absent both pyrethroid-resistant pyrethroid-sensitive An. stephensi eastern Ethiopia; however, similar information about...