Introduction: Recent studies found omega-3 fatty acid deficiency in brain cell membranes of schizophrenic patients. Conventional antipsychotics have many adverse reactions. Safety, availability and low price made as a potential supplement for treatment these This study investigated the efficacy add-on schizophrenia. Material & Methods: A randomized, double blind, placebo controlled fixed-dose, clinical trial conducted over 8 weeks. 60 patients with documented schizophrenia randomly divided...

Background and Aims: Methamphetamine abuse results in numerous adverse health effects. Formation of free radicals may be a contributing factor. has produced animal studies. Present study was conducted to evaluate status oxidative stress lipid peroxidation among chronic methamphetamine users. Methods: Ninety six individuals were selected randomly from abusers who had referred rehabilitation treatment center for drug their closed relatives, after providing informed consent. Blood samples taken...

Drug abuse can impact the function of immune cells, leading to a compromised system response. This study aimed investigate immunomodulatory effects Methamphetamine and its detoxification agents on peripheral blood dendritic cells. A total 60 participants were enrolled, including 30 individuals with addiction matched healthy controls. Participants assessed at three time points: beginning detoxification, end one-month post-detoxification. Flow cytometry was employed analyze cell subsets (CD11c...

There are few studies with conflicting results on the effects of in vivo administration opioids immune function. The aim this study was to evaluate serum levels interferon (IFN)-γ, interleukin (IL)-4, IL-10, IL-17, and hs-C-reactive protein (hs-CRP) opium smokers.The conducted between 44 male addicts controls aged 20 40 years. control group healthy individuals no lifetime history substance abuse. All abusers were selected from those who had a use opium, as regular habit, at least for 1 year,...

Background: Naloxone, as a low-priced and available drug, may be useful in improvement of signs symptoms benzodiazepines intoxication. The aim this study was assessment its effect on poisoning. Methods: In clinical-trial study, patients with typical poisoning, who were referred to poisoning center Tehran 2008, selected. After recording patients’ characteristics, supportive treatment initiated randomly assigned the case group intravenous (IV) injection two 0.4 mg naloxone ampules or control...

Rapid diagnosis of major ? thalassemia along with certain preventive measures is utmost significance. The present study aims to compare the fingerprints in Major thalassemic patients (67) and their parents (76 minor thalassemia) normal control group (144). A forensic medical examiner determined fingerprint types arch, loop, whorl other types. Like individuals, loop pattern was found be most common type among patients. However, number all fingers greater than that individuals smaller...

Currently, there is no widely accepted evidence-based pharmacotherapy regime for the treatment of psychostimulant dependence. Yet, different pharmacological approaches have been tried in MA addiction. The present study was conducted to compare efficiency methylphenidate which relatively easily accessible our country, with resperidone this purpose.Eighty-six patients dependence according criteria defined by DSM IV-TR were divided into two groups. Patients group R given oral 1 mg daily week;...

A large number of dead bodies are referred to forensic autopsy halls for medicolegal examination. They can be a source transmission infectious diseases through direct contact or tools. The main aim this study was estimate the virus infection rates in bodies. One thousand consecutive that had been hall Legal Medicine Bureau Tehran, Iran, during 2016, were included. blood samples analyzed laboratory detection HBs Ag, Ab, HIV and HCV after providing informed consent from legal next kin general...

Double layer Cation Exchange Membranes (DLCEMs) have been prepared by surface polymerization of dopamine-co-POSS nanoparticles on a PVC based heterogeneous cation exchange membrane. FTIR and FESEM images proved relatively uniform forming intended DLCEMs. The illustrated almost integrity dispensation through the layer. Results represented that developing nanocomposite resulted in hydrophilicity enhancement. obtained data for Cu2+ Cr2+ removal percentage membranes represents higher capacity...

Various drugs affect liver problems caused by general hypoxia, including silymarin. Due to the fungal killer toxins, nowadays, silymarin (milk thistle) is used as an effective drug in prevention and treatment of diseases toxicity. In addition, protects cells from solvents chemical substances. The aim this paper investigate impact on induced hypoxia.

Background: In light of severe and growing shortages clean water the rising environmental pollution in many countries, seawater desalination has been an effective method to produce freshwater. Cationic membranes have enabled scientists effectively remove toxic heavy metals from wastewater regenerate Methods: We used a novel method, involving electro- physico-chemical successfully metal ions (copper & chromium) samples. Specifically, Fourier-transform infrared spectroscopy, field emission...

Introduction: The changes in concentration of trace elements have effects on many organ systems, including the immune system. There been conflicting reports serum element levels heroin users. This study was carried out to compare concentrations opium, heroin, and methamphetamine Methods: done 90 chronically illegal drug users (n = 30 per group) controls similar sex age range (from 20 40 years). control group healthy subjects with no lifetime history substance abuse or dependence. All were...

Meperidine (pethidine) versus morphine in acute pain management of opioid-dependent patients Hassan Solhi,1 Hossein Sanaei-Zadeh,2 Sadra Mohammad Ali Azizi Nadian,1 Morteza Gharibi,3 Bahman Sadeghi Sedeh4 1Department Internal Medicine, Arak University Medical Sciences, Arak, 2Emergency Room, Division Toxicology, Hazrat Ali-Asghar (p) Hospital, Shiraz Shiraz, 3Department Emergency 4Department Social Iran Abstract: The present study aimed to evaluate the effectiveness and meperidine as relief...

According to the side effects of usual treatment burns, in improving patients' prognosis, there is a need introduce faster and more effective adjuvant therapies treat wounds, thus improve prognosis patients. The aim this study was investigate effect with oral silymarin on wound healing process caused by second degree-burns among patients admitted Valiasr Hospital Arak.This randomized, double-blind clinical trial carried out 80 second-degree burns covering 20 30 percent body flame. Patients...