A5093817895- Tryptophan and brain disorders
- Immune cells in cancer
- Gut microbiota and health
- Trace Elements in Health
- Iron Metabolism and Disorders
- Diet and metabolism studies
- Neuroinflammation and Neurodegeneration Mechanisms
University of Florence
2024-2025
The gut microbiota (MB), although one of the main producers Aβ in body, physiological conditions contributes to maintainance a healthy brain. Dysbiosis, dysbalance between Gram-negative and Gram-positive bacteria MB increases production, contributing accumulation plaques brain, histopathological hallmark Alzheimer's disease (AD). Administration prebiotics probiotics, maintaining or recovering gut-MB composition, could represent nutraceutical strategy prevent reduce AD sympthomathology. Aim...
Abstract Plasma-derived therapeutic proteins are produced through an industrial fractionation process where purified from individual intermediates, some of which remain unused and discarded. Relatively few plasma-derived exploited clinically, with most available plasma being directed towards the manufacture immunoglobulin albumin. Although proteome provides opportunities to develop novel protein replacement therapies, particularly for rare diseases, high cost together small patient...