Safi U. Khan

ORCID: 0000-0003-1559-6911
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Acute Myocardial Infarction Research
  • Cardiac Valve Diseases and Treatments
  • Health Systems, Economic Evaluations, Quality of Life
  • Atrial Fibrillation Management and Outcomes
  • Health disparities and outcomes
  • Cardiovascular Health and Risk Factors
  • Lipoproteins and Cardiovascular Health
  • Antiplatelet Therapy and Cardiovascular Diseases
  • Coronary Interventions and Diagnostics
  • Cardiac Imaging and Diagnostics
  • Heart Failure Treatment and Management
  • Infective Endocarditis Diagnosis and Management
  • Cardiovascular Function and Risk Factors
  • Venous Thromboembolism Diagnosis and Management
  • Cardiac Health and Mental Health
  • Cardiac Arrest and Resuscitation
  • Employment and Welfare Studies
  • Cardiac Arrhythmias and Treatments
  • Cardiac Structural Anomalies and Repair
  • Acute Ischemic Stroke Management
  • Pharmaceutical Economics and Policy
  • Mechanical Circulatory Support Devices
  • Cardiac, Anesthesia and Surgical Outcomes
  • Aortic Disease and Treatment Approaches
  • Diabetes, Cardiovascular Risks, and Lipoproteins

Houston Methodist
2020-2025

SUNY Upstate Medical University
2017-2025

Guthrie Robert Packer Hospital
2017-2025

West Virginia University Hospitals
2020-2025

Twitter (United States)
2024-2025

Methodist Hospital
2022-2024

Methodist Hospital
2021-2024

Government of Khyber Pakhtunkhwa
2023-2024

Yale University
2024

Wayne State University
2024

Substantial differences exist between United States counties with regards to premature (<65 years of age) cardiovascular disease (CVD) mortality. Whether underlying social vulnerabilities influence CVD mortality is uncertain.In this cross-sectional study (2014-2018), we linked county-level CDC/ATSDR SVI (Centers for Disease Control and Prevention/Agency Toxic Substances Registry Social Vulnerability Index) data CDC WONDER Prevention Wide-Ranging Online Data Epidemiological Research) data. We...

10.1161/circulationaha.121.054516 article EN Circulation 2021-10-18

Background In 1993, the US Food and Drug Administration established guidelines to increase diversity by sex race/ethnicity of participants in clinical trials supporting novel drug approvals. this study we investigated 10‐year trends participation women minorities pivotal approval new molecular entities cardiometabolic drugs from January 2008 December 2017. Methods Results A list was abstracted publicly available data at Drugs@Fda . Sex were collected trial publications. Linear regression...

10.1161/jaha.119.015594 article EN cc-by-nc-nd Journal of the American Heart Association 2020-05-19

Background Atherosclerotic cardiovascular disease ( ASCVD ) accounts for approximately one third of deaths in women. Although there is an established relationship between positive patient experiences, health-related quality life, and improved health outcomes, little known about gender differences patient-reported outcomes among patients. We therefore compared patient-centered individuals with . Methods Results Data from the 2006 to 2015 Medical Expenditure Panel Survey, a nationally...

10.1161/jaha.118.010498 article EN cc-by-nc-nd Journal of the American Heart Association 2018-12-10

<h3>Importance</h3> Interpreting randomized clinical trials (RCTs) and their relevance is challenging when<i>P</i>values are either marginally above or below the<i>P</i> = .05 threshold. <h3>Objective</h3> To use the concept of reverse fragility index (RFI) to provide a measure confidence in neutrality RCT results when assessed from perspective. <h3>Design, Setting, Participants</h3> In this cross-sectional study, MEDLINE search was conducted for RCTs published January 1, 2013, December 31,...

10.1001/jamanetworkopen.2020.12469 article EN cc-by-nc-nd JAMA Network Open 2020-08-05

Background Social and environmental factors play an important role in the rising health care burden of cardiovascular disease. The Centers for Disease Control Prevention developed Vulnerability Index (SVI) from US census data as a tool public officials to identify communities need support setting hazardous event. SVI (ranging least vulnerable score 0 most 1) ranks on 15 social including unemployment, minoritized groups status, disability, them under 4 broad themes: socioeconomic housing...

10.1161/jaha.121.024414 article EN cc-by-nc-nd Journal of the American Heart Association 2022-07-29

Background Evaluating premature (<65 years of age) mortality because acute myocardial infarction (AMI) by demographic and regional characteristics may inform public health interventions. Methods Results We used the Centers for Disease Control Prevention's WONDER (Wide-Ranging Online Data Epidemiologic Research) death certificate database to examine age-adjusted AMI rates per 100 000 average annual percentage change from 1999 2019. Overall, rate was 13.4 (95% CI, 13.3-13.5). Middle-aged...

10.1161/jaha.121.021682 article EN cc-by-nc-nd Journal of the American Heart Association 2021-12-22

Racial and social disparities exist in outcomes related to cancer cardiovascular disease (CVD). The aim of this cross-sectional study was the impact vulnerability on mortality attributed comorbid CVD. Centers for Disease Control Prevention Wide-Ranging Online Data Epidemiologic Research database (2015-2019) used obtain county-level data cancer, CVD, County-level index (SVI) (2014-2018) were obtained from CDC’s Agency Toxic Substances Registry. SVI percentiles generated each county aggregated...

10.1016/j.jaccao.2022.06.005 article EN cc-by-nc-nd JACC CardioOncology 2022-09-01

Social vulnerability index (SVI) estimates the of communities to disasters, encompassing 4 separate domains (socioeconomic, household composition and disability, minority status language, housing transportation). The SVI has been linked with risk outcomes cardiovascular disease (CVD).

10.1016/j.jacadv.2024.100858 article EN cc-by JACC Advances 2024-03-06
Coming Soon ...