A5062355651- Treatment of Major Depression
- Mental Health Research Topics
- Child and Adolescent Psychosocial and Emotional Development
- Mental Health Treatment and Access
- Child Abuse and Trauma
- Tryptophan and brain disorders
- Maternal Mental Health During Pregnancy and Postpartum
- Dementia and Cognitive Impairment Research
- Personality Disorders and Psychopathology
- Workplace Health and Well-being
- Functional Brain Connectivity Studies
- Psychotherapy Techniques and Applications
- Psychology, Coaching, and Therapy
- Healthcare professionals’ stress and burnout
- Child Welfare and Adoption
- Aging and Gerontology Research
- Cardiac Structural Anomalies and Repair
- Ethics in Clinical Research
- Psychosomatic Disorders and Their Treatments
- Mental Health and Patient Involvement
- Health, psychology, and well-being
- Cardiac Valve Diseases and Treatments
- Meta-analysis and systematic reviews
- Mindfulness and Compassion Interventions
- Patient-Provider Communication in Healthcare
University of Freiburg
2019-2025
University Medical Center Freiburg
2019-2025
University Hospital Cologne
2024
University of Tübingen
2024
University Medical Center
2021-2024
German Center for Neurodegenerative Diseases
2024
University of Cologne
2024
Leipzig University
2024
University Hospital Bonn
2024
Heidelberg University
2024
Effect sizes of psychotherapies currently stagnate at a low‐to‐moderate level. Personalizing psychotherapy by algorithm‐based modular procedures promises improved outcomes, greater flexibility, and better fit between research practice. However, evidence for the feasibility efficacy modular‐based psychotherapy, using personalized treatment algorithm, is lacking. This proof‐of‐concept randomized controlled trial was conducted in 70 adult outpatients with primary DSM‐5 diagnosis major...
Child maltreatment is a broadly confirmed risk factor for mental and physical illness. Some psychological treatments specifically target health conditions associated with child maltreatment. For example, the Cognitive Behavioral Analysis System of Psychotherapy (CBASP) focuses on maladaptive interpersonal behaviours in chronic depression. However, how assessment could inform personalised treatment unclear. We used data from previously published clinical trial to investigate whether...
Importance Conceptualizing mental disorders as latent entities has been challenged by the network theory of disorders, which states that psychological problems are constituted a mutually interacting symptoms. While implications approach for planning and evaluating treatments have intensively discussed, empirical support claims regarding treatment effects is lacking. Objective To assess extent to specific hypotheses derived from (interindividual) changeability symptom dynamics in response...
Introduction: Different psychotherapeutic interventions for late-life depression (LLD) have been proposed, but their evaluation in large, multicenter trials is rare. Objective: The present study evaluated the efficacy of a specific cognitive behavioral therapy (CBT) LLD (LLD-CBT) comparison with supportive unspecific intervention (SUI), both administered specialist psychiatric outpatient setting. Methods: In this randomized, controlled, parallel group trial, we recruited participants (≥60...
Importance Physical diseases co-occur with late-life depression (LLD). The influence of physical and the subjective perception health (PPH) on treatment outcome in LLD, however, is not well understood. Objective To assess association PPH outcomes 2 different types psychotherapy LLD. Design, Setting, Participants This post hoc secondary analysis a multicenter, observer-blinded, controlled, parallel-group randomized clinical trial assessed participants 60 years or older moderate to severe...
<b><i>Background:</i></b> Evidence on the long-term efficacy of psychotherapeutic approaches for chronic depression is scarce. <b><i>Objective:</i></b> To evaluate effects Cognitive Behavioral Analysis System Psychotherapy (CBASP) compared to Supportive (SP) 1 year and 2 years after treatment termination. <b><i>Methods:</i></b> In this study, we present 1- 2-year follow-up assessments a prospective, multicenter,...
Introduction In depression treatment, most patients do not reach response or remission with current psychotherapeutic approaches. Major reasons for individual non-response are interindividual heterogeneity of etiological mechanisms and pathological forms, a high rate comorbid disorders. Personalised treatments targeting comorbidities as well underlying transdiagnostic factors like early childhood maltreatment may lead to better outcomes. A modular-based psychotherapy (MoBa) approach provides...
Zusammenfassung Das Prinzip der Modularität ist ein vielversprechender Ansatz, um Psychotherapie zu personalisieren. Bislang gibt es jedoch keine Evidenz, wie modulare („modular-based psychotherapy“, MoBa) anhand eines systematischen Behandlungsalgorithmus für erwachsene Patient:innen umgesetzt werden kann. Deshalb wurden in dieser Proof-of-Concept-Studie 70 mit Depression, komorbiden psychischen Störungen und einer Vorgeschichte von Kindesmisshandlung randomisiert MoBa oder herkömmlichen...
Abstract Background Depression associated with occupational stress is highly prevalent, causing high rates of sick leave and thus posing significant societal economic burden. Meta-analyses the few studies on psychological work-focused interventions for common mental disorders including depression report small effects depressive symptomatology outcomes. There an urgent need more controlled work-directed assessing work Methods This interventional, multicentre, active-controlled,...
Background: Depressive disorders are among the leading causes of sick leave and long-term work incapacity in most modern countries. Work related stress is described by patients as common context depression. It vital to know what types treatments effective improving problems occupational health. However, there only limited evidence on work-focused interventions. Methods: The aim our study was evaluate feasibility generate first data effectiveness Interpersonal Psychotherapy (IPT) adapted a...
For relapse prevention in depression, conventional mindfulness programs such as the mindfulness-based cognitive therapy proved to be useful. However, early life trauma is a risk factor for having adverse experiences during meditation. Thus, this patient group skills are often difficult learn and may facilitated by using animals nature setting.The aim of study was evaluate preventative efficacy nature- animal assisted program (NAM) over course 1 year unstable or partially remitted depressed...
<b><i>Introduction:</i></b> In clinical trials, mostly group-level treatment effects of repeated cross-sectional measures are analyzed. However, substantial heterogeneity regarding individual symptom profiles and the variability often neglected, especially over long-term course. To provide effective personalized treatments, investigations these characteristics urgently needed. <b><i>Methods:</i></b> Depression severity ratings 104 weeks...
We comment on the papers by Schönbrodt et al. (2022) and Gärtner responsible research assessment from perspective of clinical psychology psychotherapy research.
Difficulties in emotion regulation are an essential transdiagnostic phenomenon of mental health. While there is extensive literature focusing on difficulties as trait-like constructs, it inherently a dynamic process that unfolds over time. This raises the need for state-like measures to capture these temporal dynamics both laboratory and real-world settings, such State Emotion Regulation Scale (S-DERS). In present study, we report German translation validation S-DERS cross-sectional network...
We comment on the papers by Schönbrodt et al. (2022) and Gärtner responsible research assessment from perspective of clinical psychology psychotherapy research. propose four principles to guide hiring promotion in psychology: (1) In addition publications scientific journals, data sets development software should be considered. (2) Quantitative metrics can useful, but they valid applied responsibly. (3) Methodological rigor, impact, work quantity considered as three separate dimensions for...