A5100413386- Nanoparticles: synthesis and applications
- Graphene and Nanomaterials Applications
- Nanoparticle-Based Drug Delivery
- Nanoplatforms for cancer theranostics
- Carbon and Quantum Dots Applications
- Advanced Nanomaterials in Catalysis
- Catalytic Processes in Materials Science
- Electrocatalysts for Energy Conversion
- Nanocluster Synthesis and Applications
- Advanced biosensing and bioanalysis techniques
- Nanocomposite Films for Food Packaging
- Advanced battery technologies research
- Atmospheric chemistry and aerosols
- Quantum Dots Synthesis And Properties
- Analytical Chemistry and Chromatography
- Advanced Chemical Sensor Technologies
- Energy, Environment, Economic Growth
- Catalysis and Oxidation Reactions
- Mesoporous Materials and Catalysis
- Advanced Photocatalysis Techniques
- Atmospheric Ozone and Climate
- Plant Pathogens and Fungal Diseases
- Gas Sensing Nanomaterials and Sensors
- Supercapacitor Materials and Fabrication
- Heavy Metal Exposure and Toxicity
ZheJiang Academy of Agricultural Sciences
2011-2025
Chinese Academy of Medical Sciences & Peking Union Medical College
2025
Institute of Plant Protection
2011-2025
Shanxi University
2012-2025
First Affiliated Hospital of Henan University
2019-2025
Shanghai University
2015-2024
Capital Medical University
2024
Hainan Medical University
2022-2024
Huazhong Agricultural University
2024
State Key Laboratory of Chemical Engineering
2010-2024
A FRET-based carbon nanodot (CDot) drug delivery platform has been developed. These CDots offer excellent biocompatibility, stable fluorescence, and efficient FRET between the attached fluorescent molecules, such as doxorubicin, enabling enhanced delivery, convenient cell imaging, real-time monitoring of release. Moreover, two-photon imaging tracking in deep tissues are also demonstrated. As a service to our authors readers, this journal provides supporting information supplied by authors....
Given the intensive application of nanoscale zinc oxide (ZnO) materials in our life, growing concerns have arisen about its unintentional health and environmental impacts. In this study, neurotoxicity different sized ZnO nanoparticles mouse neural stem cells (NSCs) was investigated. A cell viability assay indicated that manifested dose-dependent, but no size-dependent toxic effects on NSCs. Apoptotic were observed analyzed by confocal microscopy, transmission electron microscopy examination,...
Nanoparticles are expected to play a vital role in the management of future plant diseases, and they provide an environmentally friendly alternative traditional synthetic fungicides. In present study, silver nanoparticles (AgNPs) were green synthesized through mediation by using endophytic bacterium Pseudomonas poae strain CO, which was isolated from garlic plants (Allium sativum). Following confirmation analysis that used UV–Vis, we examined vitro antifungal activity biosynthesized AgNPs...
Abstract Size, shape, and protein corona play a key role in cellular uptake removal mechanisms of gold nanoparticles (Au NPs). The 15 nm (NP1), the 45 (NP2), rod‐shaped (NR) enter into cells via receptor‐mediated endocytosis (RME) pathway. star‐shaped (NS) adopt not only clathrin‐mediated, but also caveolin‐mediated pathways. However, 80 nanoparitcles (NP3) mainly by macropinocytosis pathway due to big size. Furthermore, results indicate that presence can change Au NPs. NP1, NP2, NS changes...
Abstract Defect engineering is an emerging technology for tailoring nanomaterials' characteristics and catalytic performance in various applications. Recently, defect‐engineered nanoparticles have emerged as highly researched materials applications because of their exceptional redox reaction capabilities physicochemical optical properties. The properties nanomaterials can be readily adjusted by controlling the nature concentration defects within nanoparticles, avoiding need intricate design...
Fullerenes as a unique class of carbon allotropes have been studied extensively for their distinctive material properties and potential technological applications, including those in biology medicine. Since major focus the latter has on drug development formulation, this paper we highlight some representative studies related to such focus, use fullerenes drug-like functions improving formulation established drugs. Also discussed are other medically relevant applications fullerenes, serving...
Nanoscale carbon particles have emerged as versatile precursors for a new class of highly fluorescent nanomaterials that resemble semiconductor quantum dots. The surface-passivated nanoparticles, dubbed 'carbon dots', were already demonstrated their potential optical bioimaging applications in vitro and vivo. In this study, we conducted systematic cytotoxicity evaluation on the dots prepared by various combinations precursor nanoparticles molecules particle surface functionalization. results...
Engineered nanomaterials (ENMs) are increasingly added to foods improve their quality, sensory appeal, safety and shelf-life. Human exposure these ingested ENMs (iENMS) is inevitable, yet little known of hazards. To assess potential hazards, efficient in vitro methodologies needed evaluate particle biokinetics toxicity. These must account for interactions transformations iENMs (food matrix effect) the gastrointestinal tract (GIT) that likely determine nano-biointeractions. Here we report...
Abstract Nitrate (NO 3 − ), which is mainly oxidized from NO 2 by the OH radical (OH·) and O in atmosphere, a major component of inorganic aerosols. However, contributions OH· pathways to urban aerosols influence air pollution both remain unclear. Oxygen isotopes were measured for PM 2.5 Beijing 2014. The Δ 17 O‐NO values (17.0–32.8‰) significantly higher winter (27.2 ± 3.6‰) than summer (24.2 1.3‰). By estimating x cycle, endmembers produced via + (P1), · DMS/HC (P2), N 5 hydrolysis (P3)...
At present, safety evaluation standards for nanofood additives are made based on the toxic effects of a single additive. Since size, surface properties and chemical nature influence toxicity nanomaterials, may have dramatically changed when nanomaterials used as food in complex system. Herein, we investigated combined zinc oxide nanoparticles (ZnO NPs) vitamin C (Vc, ascorbic acid). The results showed that Vc increased cytotoxicity significantly compared with ZnO only NPs. When cells were...
Edible plant fruits are safe raw materials free of toxicants and rich in biomolecules for reducing metal ions stabilizing nanoparticles. Zinc oxide nanoparticles (ZnONPs) titanium dioxide (TiO2NPs) the most produced consumer nanomaterials have known antibacterial activities but rarely been used against phytopathogenic bacteria. Here, we synthesized ZnONPs TiO2NPs simply by mixing ZnO or TiO2 solution with a lemon fruit extract at room temperature showed their Dickeya dadantii, which causes...
Abstract Tumor extracellular matrix (ECM) not only forms a physical barrier for T cells infiltration, but also regulates multiple immunosuppressive pathways, which is an important reason immunotherapy failure. The cyclic guanosine monophosphate‐adenosine monophosphate synthase‐stimulator of interferon genes (cGAS‐STING) pathway plays key role in activating CD8 + cells, maintaining stemness and enhancing the antitumor effect. Herein, zinc‐organometallic framework vaccine (ZPM@OVA‐CpG)...
Abstract Resveratrol, curcumin, and quercetin are the secondary metabolites from medicinal food homology plants, that have been proven their potency in cancer treatment. However, antitumor effect of a single component is weak. So, herein, we designed an compound named RCQ composed resveratrol, quercetin. This study examined on tumorigenesis development 4T1 breast cancer-bearing mice following administering by intragastric administration. increased recruitment T cells reduced accumulation...
ABSTRACT Silica nanoparticles (NPs) have been widely used in food products as an additive; however, their toxicity and safety to the human body environment still remain unclear. As a additive, silica NPs firstly enter gastrointestinal tract along with food, thus deserves thorough study. Herein, we evaluated of additive cells originating from tract. Four NP samples were introduced gastric epithelial cell GES‐1 colorectal adenocarcinoma Caco‐2 investigate effect sample, exposure dose period on...