A5101968926- Cancer therapeutics and mechanisms
- Phytochemistry and Bioactivity Studies
- Fungal Biology and Applications
- Dermatology and Skin Diseases
- Cervical Cancer and HPV Research
- Influenza Virus Research Studies
- Berberine and alkaloids research
- Synthesis and bioactivity of alkaloids
- Hepatitis B Virus Studies
- Allergic Rhinitis and Sensitization
- Reproductive Physiology in Livestock
- Liver Disease Diagnosis and Treatment
- Immune Cell Function and Interaction
- Inflammatory mediators and NSAID effects
- Vaccine Coverage and Hesitancy
- Traditional Chinese Medicine Analysis
- Polysaccharides and Plant Cell Walls
- Immune Response and Inflammation
- Cancer, Stress, Anesthesia, and Immune Response
- Mast cells and histamine
- Metabolomics and Mass Spectrometry Studies
- Alcohol Consumption and Health Effects
- interferon and immune responses
- Reproductive System and Pregnancy
Chengdu University of Traditional Chinese Medicine
2008-2024
To observe the effect of volatile oil Schizonepetae Herba (VOSH), and its essential components-menthone pulegone against anti-influenza virus A/PR/8/34 (H1N1) in vivo vitro, as well signaling mechanism toll-like receptor/interferon (TLR/IFN).The lung-adapted PR-8 model was prepared mice. They were administered with preventive therapeutic drugs, hemagglutination titer animals determined to evaluate H1N1. ELISA test conducted on IFN-alpha, IFN-beta, IL-2, IL-6 TNF-alpha serum, IFN-beta...
Abstract Background Premature ovarian insufficiency (POI) is an immune-related condition. Dihydroberberine (dhBBR) plays a regulatory role in maintaining the T-helper 17 (Th17)/regulatory T (Treg) cell balance. This study aimed to explore action mechanisms of dhBBR on POI. Methods In vivo, female BALB/c mice were used as POI models, treated with dhBBR, or injected recombinant interleukin (rIL)-17 and anti-CD25 monoclonal antibody. Hematoxylin eosin staining was validate model assess...
The present study explored the potential mechanism of Jingfang Granules in relieving alcohol and protecting liver by network pharmacology molecular docking verified effects related pathways animal experiments. active components were retrieved from Traditional Chinese Medicine Systems Pharmacology Database Analysis Platform(TCMSP). Targets drugs diseases obtained PubChem, Swiss Target Prediction CTD. common targets uploaded to STRING plot protein-protein interaction(PPI) network. core...
In order to study the protective effects of Schizonepeta volatile oil (Sto）on endotoxin poisoning mice, and relatively content each chemical osubstance in was measured using GC-MS. The mare C57BL/6J mice were randomly divided into five groups including normal group, model dexamethasone group (5 mg•kg⁻¹), Sto (0.226 0.452 g•kg⁻¹, respectively) groups. given drugs once time by intraperitoneal injection on 5th day, while other oral administration a day for 5 days. Then, injected with saline LPS...