Declined cognitive function interferes with dual-task walking ability and may result in falls older adults mild impairment (MCI). The mind-body exercise, Tai Chi (TC), improves cognition ability. Exergaming is low-cost, safe, highly scalable, feasible. Whether the effects of exergaming-based TC beneficial than traditional has not been investigated yet.The objective this study was to investigate on among MCI.Fifty patients MCI were randomly assigned an (EXER-TC) group, a (TC) or control...

Abstract Background Older adults with Mild Cognitive Impairment (MCI) are often subject to cognitive and gait deficits. Interactive Computerized Training (ICCT) may improve function; however, the effect of such training on performance is limited. Transcranial Direct Current Stimulation (tDCS) improves cognition performance. It remains unclear whether combining tDCS ICCT produces an enhanced synergistic complex relative alone. This study aimed compare effects combined in older MCI. Method...

Background and Purpose: Motoric cognitive risk syndrome (MCR) is a predementia strong predictor of Alzheimer’s disease (AD). Functional mobility, such as balance, sit-stand transitions, turning, has not been clearly investigated in this population. This study aimed to compare functional mobility among older adults with normal cognition (NC), MCR, mild AD. Cognitive-motor interactions were also all the groups. Methods: cross-sectional included 91 adults, including 36 NC, 32 23 A battery...

Background: Motoric Cognitive Risk Syndrome (MCR), defined by the co-occurrence of subjective cognitive complaints and slow gait, is recognized as a preclinical risk state for decline. However, not all individuals with MCR experience deterioration, making early individualized prediction critical. Methods: This study included 80 participants aged 60 older who underwent baseline assessments including plasma biomarkers (β-amyloid, tau), dual-task gait measurements, neuropsychological tests....

Previous studies showed that multicomponent exercise enhanced physical and cognitive functions. This study aimed to investigate the effects of a on dual-task performance executive function demonstrate relationship between improvement in enhancement among elderly. A total 27 people completed intervention, with 16 experimental group 11 control group. The 12-week lasted 1 h per day 3 days week. Participants' gait was assessed conditions examined at both pre- post-intervention. Results...

Abstract Background Motoric cognitive risk syndrome (MCR) is defined by slow gait speed combined with subjective complaint. MCR a predementia syndrome, similar to mild impairment (MCI). However, there currently no study comparing the differences in performance and physical function between these two types of impairment. Thus, aim this compare individuals versus MCI. Methods A total 77 participants, free dementia, were recruited from neurological outpatient clinic medical center Taiwan....

Cognitive impairment is an important non-motor aspect of Parkinson's disease (PD). Amyloid-β and tau pathologies are well-established in Alzheimer's commonly coexist with synucleinopathy PD. However, the levels these biomarkers plasma patients PD their relationship specific cognition domains remain to be clarified. The current study compared motor severity neuropsychological assessment general cognition, α-synuclein (α-syn), amyloid-β 42 (Aβ42), total (t-tau) subjects.Plasma α-syn, Aβ42,...

Background Motoric cognitive risk (MCR) syndrome is a conceptual construct that combines slow gait speed with subjective complaints and has been shown to be associated an increased of developing dementia. However, the relationships between pathology Alzheimer’s disease (AD) MCR remain uncertain. Therefore, purpose this study was determine levels plasma AD biomarkers (Aβ42 total tau) their cognition in individuals MCR. Materials methods This cross-sectional pilot enrolled 25 normal (NC), 27...

Far-infrared radiation (FIR) therapy improves vessel dilation, circulation, endothelial function, and angiogenesis reduces atherosclerosis. However, evidence of FIR therapy's effects on foot circulation among diabetic patients undergoing hemodialysis is scarce.To determine whether in hemodialysis.Quasi-experimental.In June to November 2017, (N = 58) at a center northern Taiwan were divided into two groups: the experimental group (n 31) received bilateral dorsalis pedis artery (40...

Mild cognitive impairment (MCI) is considered an intermediate state between normal aging and early dementia. Fear of falling (FOF) could be a risk indicator for falls quality life in individuals with MCI. Our objective was to explore factors associated FOF those MCI due Alzheimer's disease (AD-MCI) mild Parkinson's (PD-MCI). Seventy-one participants were separated into two groups, AD-MCI (n = 37) PD-MCI 34), based on the diagnosis. assessed using Activities-specific Balance Confidence scale....

This study developed a predictive model for cognitive degeneration in patients with Parkinson’s disease (PD) using machine learning method. The clinical data, plasma biomarkers, and neuropsychological test results of PD were collected utilized as predictors. Machine methods comprising support vector machines (SVMs) principal component analysis (PCA) applied to obtain classification model. Using 32 comprehensive parameters, the PCA-SVM classifier reached 92.3% accuracy 0.929 area under...

The purpose of this study was to investigate the effects a specific exercise (SE) training program focusing on balance and muscle strengthening turning-based treadmill (TT) cortical desynchronization postural control in Parkinson's disease (PD).

We conducted an observational study to investigate clinical predictors of cognitive decline in patients with mild impairment (MCI), a focus on Parkinson’s disease (PD) and Alzheimer’s (AD). The was performed detailed neuropsychological testing, portable device for gait analysis, comprehensive geriatric assessment MCI. Cognitive defined as subjective objective the Mini-Mental State Examination (MMSE) ≥2 points at one-year follow-up. Participants (n = 74) had median age 70 (interquartile range...

Surface Mechanomyography (MMG) is the recording of mechanical activity muscle tissue. MMG measures signal (vibration muscle) that generated from muscles during contraction or relaxation action. This project determined to focus on study and develop suitable procedures methods analyze classify biceps exercise using Signals. There are two channels has been placed into brachii (Short Head Biceps Brachii Long Brachii) by VMG sensor (TSD250A) with different weights. Five features have selected...

Abstract Background Motoric cognitive risk syndrome (MCR) is defined by slow gait speed combined with subjective complaint. MCR a predementia syndrome, similar to mild impairment (MCI). However, there currently no study comparing the differences in performance and physical function between these two types of impairment. Thus, aim this compare individuals versus MCI. Methods A total 77 participants, free dementia, were recruited from neurological outpatient clinic medical center Taiwan....

We have created an innovative new method which uses frequency domain near-infrared spectroscopy (FDNIRS) in combination with diffuse correlation (DCS) to quantitatively measure cerebral blood flow (CBF) and oxygen metabolism (CMRO 2 ) right at the infant’s bedside. previously found CBF CMRO are more sensitive indicators of pathophysiology than hemoglobin saturation (SO ). Using FDNIRS-DCS, we had extremely premature infants germinal matrix hemorrhage (GMH) lower gestational age-matched...

Abstract Background Motoric cognitive risk syndrome (MCR) is defined by slow gait speed combined with subjective complaint. MCR a predementia syndrome, similar to mild impairment (MCI). However, there currently no study comparing the differences in performance and physical function between these two types of impairment. Thus, aim this compare individuals versus MCI. Methods A total 77 participants, free dementia, were recruited from neurological outpatient clinic medical center Taiwan....

Abstract Background Motoric cognitive risk syndrome (MCR) is defined by slow gait speed combined with subjective complaint. MCR a predementia syndrome, similar to mild impairment (MCI). However, there currently no study comparing the differences in performance and physical function between these two types of impairment. Thus, aim this compare individuals versus MCI. Methods A total 77 participants, free dementia, were recruited from neurological outpatient clinic medical center Taiwan....

Abstract BackgroundMotoric cognitive risk syndrome (MCR) is defined by slow gait speed combined with subjective complaint. MCR a predementia syndrome, similar to mild impairment (MCI). However, there currently no study comparing the differences in performance and physical function between these two types of impairment. Thus, aim this compare individuals versus MCI. MethodsA total 77 participants, free dementia, were recruited from neurological outpatient clinic medical center Taiwan....