A5036073328- Aortic Disease and Treatment Approaches
- Cardiac Structural Anomalies and Repair
- Mechanical Circulatory Support Devices
- Cardiac Valve Diseases and Treatments
- Infective Endocarditis Diagnosis and Management
- Cardiac, Anesthesia and Surgical Outcomes
- Aortic aneurysm repair treatments
- Cardiac Ischemia and Reperfusion
- Cardiac Arrest and Resuscitation
- Transplantation: Methods and Outcomes
- Cardiac tumors and thrombi
- Infectious Aortic and Vascular Conditions
- Respiratory Support and Mechanisms
- Nitric Oxide and Endothelin Effects
- Cardiovascular Effects of Exercise
- Cardiac and Coronary Surgery Techniques
- Pleural and Pulmonary Diseases
- Cardiovascular Issues in Pregnancy
- Vasculitis and related conditions
- Renal Transplantation Outcomes and Treatments
- Vascular Tumors and Angiosarcomas
- Hip and Femur Fractures
- Cardiac Fibrosis and Remodeling
- Esophageal and GI Pathology
- Polyomavirus and related diseases
NorthShore University HealthSystem
2022-2025
Rush University Medical Center
2015-2024
Boston Medical Center
2017-2024
Boston University
2017-2024
Swedish Covenant Hospital
2024
University Medical Center
2019-2024
Brown University
2011-2024
North Shore University Hospital
2023
Rhode Island Hospital
2011-2022
Tufts Medical Center
2022
There is growing recognition that adipose tissue-derived proatherogenic mediators contribute to obesity-related cardiovascular disease. We sought characterize regional differences in perivascular tissue (PVAT) phenotype relation atherosclerosis susceptibility. Approach and Results: examined thoracic PVAT samples 34 subjects (body mass index 32±6 kg/m2, age 59±11 years) undergoing valvular, aortic, or coronary artery bypass graft surgeries performed transcriptomic characterization using...
Background Aortic dissection (AD) during pregnancy and puerperium is a rare catastrophe with devastating consequences for both parent fetus. Population‐level incidence trends outcomes remain relatively undetermined. Methods Results We queried US population‐based health care database, the National Inpatient Sample, identified all patients pregnancy‐related AD hospitalization from 2002 to 2017. In total, 472 hospitalizations (mean age, 30.9±0.6 years) were 68 514 000 (0.69 per 100...
Background— We investigated the effects of cardiopulmonary bypass (CPB) on peripheral arteriolar reactivity and associated signaling pathways in poorly controlled (UDM), (CDM), case-matched nondiabetic (ND) patients undergoing coronary artery grafting (CABG). Methods Results— Skeletal muscle arterioles were harvested before after CPB from UDM (hemoglobin A1c [HbA1c]=9.0±0.3), CDM (HbA1c=6.3±0.15), ND (HbA1c=5.2±0.1) CABG surgery (n=10/group). In vitro relaxation responses precontracted to...
ABSTRACT Background This study aims to analyze the patient characteristics, clinical outcomes, and contemporary trends concerning type A aortic dissection (TAAD) in previous recipients of abdominal solid organ transplantation (ASOT) United States. Methods The National Inpatient Sample was queried identify all patients aged ≥18 with TAAD a history ASOT (TAAD‐ASOT) between 2002 2015Q3 using ICD‐9 diagnosis procedure codes. Baseline characteristics in‐hospital outcomes were compared TAAD‐ASOT...
Psychosocial factors are useful predictors of adverse outcomes after solid organ transplantation. Although depression is a known predictor poor in patients who undergo orthotopic heart transplantation (OHT) and actively screened for during pre-transplant evaluation, the effects early identification this entity on post-transplant not clearly understood. The purpose study was to evaluate impact OHT. In retrospective study, 51 that underwent psychosocial evaluation performed by social worker...
Extracorporeal membrane oxygenation (ECMO) offers an opportunity for patient recovery through complete cardiopulmonary support but is associated with complications that limit duration and overall utility. We examine the role of ECMO as a potential bridge to high-risk cardiac surgery in otherwise inoperable cases. This study reports retrospective, multi-institution experience examining all patients whom was used preoperatively definitive without exception. A consecutive database (December...
We investigated the effects of cardioplegic arrest and reperfusion (CP/Rep) on myocardial apoptosis key apoptotic mediators, such as apoptosis-inducing factor, caspase 3, 8, 9, poly(adenosine diphosphate-ribose) polymerase, B-cell lymphoma 2 (Bcl-2) family proteins, protein kinase C (PKC), in uncontrolled type diabetic, controlled nondiabetic patients. Right atrial tissue was harvested pre- post-CP/Rep from diabetic patients (hemoglobin A1c=9.6 ± 0.25), A1c=6.5 0.15), A1c=5.4 0.12)...
The effect of the lunar cycle and seasonal variation on ascending aortic dissection surgery outcomes is unknown. We investigated these temporal effects risk-adjusted hospital mortality then length stay (LOS) following for survivors. examined prospectively collected data from cardiac operations at two major centres within a single state between January 1996 December 2011. first relationship variation, along with demographic risk profile covariates, using univariate analyses, followed by...
OBJECTIVES: Extracorporeal membrane oxygenator support is a powerful clinical tool that currently enjoying resurgence in popularity. Wider use of extracorporeal limited by its significant risk profile and extreme consumption resources. This study examines the role markers liver dysfunction predicting outcomes adult patients requiring support. DESIGN: Retrospective review. SETTING: Large center, Chicago, IL. PATIENTS: reports single institution experience examining all for whom was used over...
Redo cardiac surgery for aortic valve replacement (AVR) after previous coronary artery bypass grafting (CABG) is technically challenging and carries a high incidence of peri-operative complications. However, experience in the field continues to evolve generating reproducible, increasingly safer results. We anticipate an increased future role catheter-based procedures review our operative results maintain current surgical outcomes comparison. A retrospective was conducted from 1996 through...