A5015325983- Acute Myeloid Leukemia Research
- Chronic Myeloid Leukemia Treatments
- Chronic Lymphocytic Leukemia Research
- Acute Lymphoblastic Leukemia research
- Immune Cell Function and Interaction
- Liver Disease Diagnosis and Treatment
- Iron Metabolism and Disorders
- Immune cells in cancer
- Cardiac Imaging and Diagnostics
- Hemoglobinopathies and Related Disorders
- Hematological disorders and diagnostics
- Diet and metabolism studies
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Alcoholism and Thiamine Deficiency
- Hematopoietic Stem Cell Transplantation
- Diabetes and associated disorders
- Metabolism and Genetic Disorders
- Eosinophilic Disorders and Syndromes
- Healthcare during COVID-19 Pandemic
- Cardiovascular and Diving-Related Complications
- Diabetes Management and Research
- Cardiovascular Function and Risk Factors
- COVID-19 Clinical Research Studies
- Lipid metabolism and disorders
- CAR-T cell therapy research
Universidade de São Paulo
2020-2024
Instituto do Câncer do Estado de São Paulo
2023-2024
Universidade de Ribeirão Preto
2020-2022
Clinics Hospital of Ribeirão Preto
2021
Universidade Estadual de Campinas (UNICAMP)
2017-2018
Coordenação de Aperfeicoamento de Pessoal de Nível Superior
2018
Instituto Universitario Aeronáutico
2010
Hospital Privado
2004
Acute myeloid leukaemia (AML) is considered a costly disease. Depending on the risk stratification, patient may receive consolidation with cycles of intermediate doses cytarabine, auto-HSCT or allo-HSCT according to availability in each service and compatible donor. Literature data indicate that safety effectiveness do not differ between therapy intermediate-dose cytarabine auto-HSCT, so cost can help physicians health managers their choice.
Objectives: To establish the prevalence, clinical features, and outcomes of recently recog- nized stress cardiomyopathy whose physiopathology is still not completely clarified. Material methods: The prevalence findings were assessed in a group 378 patients undergoing cinecoronariography for acute coronary syndromes dur- ing 7-year period. inclusion criteria severe chest pain, ischemic electrocardiogra- phic changes, reversible left ventricular dys- hypokinesia, normal arteries. Eight...
In cancer, tumor cells and their neoplastic microenvironment can sculpt the immunogenic phenotype of a developing tumor. this context, natural killer (NK) are subtypes lymphocytes innate immune system recognized for potential to eliminate cells, not only through direct cytolytic activity but also by favoring development an adaptive antitumor response. Even though protective effect against leukemia due NK-cell alloreactivity mediated absence KIR-ligand has already been shown, some data on...
A COVID-19 é uma infecção causada pelo vírus SARS-CoV-2, descrita no final de 2019, que ocasionou pandemia devido à sua alta transmissibilidade. Em geral, cursa sem alterações clínicas ou com sintomas leves, porém em 5-10% dos casos pode causar quadros graves, inclusive óbito. Manifestações críticas parecem mais comuns indivíduos comorbidades como hipertensão arterial sistêmica e obesidade. Entretanto, a descrição da doença recente, há poucos estudos esclareçam história natural o grande...
Acute myeloid leukemia with monocytic blast differentiation (AML-MC) is a rare malignancy (5-10% incidence) challenging diagnosis, classified as "non otherwise specified" AML (AML NOS), unless recurrent genetic abnormalities, therapy-related or associated myelodysplasia-related changes are reported (WHO 2017). We observed high incidence of AML-MC and aimed to assess its molecular immunophenotypic features in multicenter study Brazil. 387 bone marrow samples (18-84 years old) from 10...
Despite well-known Natural Killer (NK) cells antitumor activity, its potential in regulating Chronic Myeloid Leukemia (CML) is not fully stablished. Tyrosine kinase inhibitors (TKI) treatment, besides reducing BCR-ABL1 transcripts, seems to result immunomodulation that partly restore the immune dysregulation of disease. Numerical, functional and maturation defects might be associated with CML risk stratification, molecular response profile or even resistance treatment TKI. Therefore, we...
<title>Abstract</title> <bold>Background:</bold> Acute myeloid leukemia (AML) is considered a costly disease. Although induction of remission critical factor for overall survival (OS) in patients with AML, the fundamental decision after best post-remission treatment strategy. Depending on risk stratification, patient may receive consolidation cycles intermediate doses cytarabine, auto-HSCT or allo-HSCT, according to availability each service and compatible donor. Both strategies are valid...