A5007789662- Corneal surgery and disorders
- Glaucoma and retinal disorders
- Intraocular Surgery and Lenses
- Corneal Surgery and Treatments
- Traumatic Ocular and Foreign Body Injuries
- Ocular Surface and Contact Lens
- Facial Trauma and Fracture Management
- Ocular Infections and Treatments
- Ophthalmology and Eye Disorders
- Retinal Diseases and Treatments
- Nasolacrimal Duct Obstruction Treatments
- Ophthalmology and Visual Impairment Studies
- Ocular Diseases and Behçet’s Syndrome
- Ocular Oncology and Treatments
- Retinal Development and Disorders
- Cerebral Venous Sinus Thrombosis
- Retinal and Optic Conditions
- Cancer and Skin Lesions
- Retinal and Macular Surgery
- Microbial Inactivation Methods
- Biomedical Research and Pathophysiology
- Ocular Disorders and Treatments
- Sinusitis and nasal conditions
- Photodynamic Therapy Research Studies
- Microfluidic and Bio-sensing Technologies
Martin Luther University Halle-Wittenberg
2017-2025
University Hospital in Halle
2018-2025
Saarland University
2011-2024
Klinik und Poliklinik für Augenheilkunde Universitätsklinikum Regensburg
2018-2023
Universitätsklinikum des Saarlandes
2012-2019
Ophthalmology Clinic
2012-2019
Novem (Netherlands)
2018
Ophthalmology Associates (United States)
2016
Otto-von-Guericke University Magdeburg
2007-2012
May Institute
2011
To evaluate the rotational stability of eye during standard photography and determine its effect on measurement toric intraocular lens (IOL) orientation.Department Ophthalmology, University Erlangen-Nuremberg, Erlangen, Germany.The was evaluated using photographs taken with a telecentric fundus camera (Zeiss). Two sets images were at least 6 months apart in 400 eyes 200 patients. The axial position determined 2 characteristic markers fundus. angle between (autorotation angle) measured each...
The aim of our study was to investigate the biomechanical properties cornea in primary congenital glaucoma (PCG) and identify potential ocular determinants, which affect corneal metrics.Corneal hysteresis (CH), resistance factor (CRF) central thickness (CCT) were measured 26 patients with PCG (40 eyes) aid response analyser. In vivo laser-scanning confocal microscopy used for estimation stromal keratocyte density (KD) evaluation endothelium. Twenty normal subjects served as controls....
The purpose of our research was the development Amphotericin B-loaded in situ gelling nanofibers for treatment keratomycosis. Different formulation strategies were applied to increase drug load sparingly water-soluble B electrospun Gellan Gum/Pullulan fibers. These include bile salt addition, encapsulation poly(lactic-co-glycolic acid) (PLGA) nanoparticles and formation a polymeric polyelectrolyte complex. complex (AmpB-Eu L) performed best very effective against fungal strain Issatchenkia...
Uveal melanoma (UM) is the most common primary intraocular tumor that arises from neoplastic melanocytes in choroid, iris, and ciliary body. Electrochemotherapy (ECT) has been successfully established for treatment of skin soft tissue metastatic lesions, deep-seated tumors liver, bone metastases, unresectable pancreas lesions. The aim this study was to evaluate effect ECT vitro 3D spheroid culture systems UM cell lines. We also investigated chick embryo chorioallantoic membrane (CAM) as an...
Hintergrund Okuläre Traumen sind Ursache für jede dritte Enukleation. Stumpfe zählen zu den häufigsten okulären Verletzungen. Mittels Analyse der Augenverletzungen sollen detaillierte epidemiologische Daten gewonnen werden.Patienten und Methoden Retrospektive von 417 Patienten, die 1985 bis 1995 in Universitäts-Augenklinik Erlangen wegen Bulbuskontusion oder Bulbusruptur stationär aufgenommen behandelt wurden (EOCR - Erlanger Okuläres Contusions-Register).Ergebnisse Ein Drittel Verletzungen...
Abstract Biallelic STX3 variants were previously reported in five individuals with the severe congenital enteropathy, microvillus inclusion disease (MVID). Here, we provide a significant extension of phenotypic spectrum caused by variants. We report ten diverse geographic origin biallelic loss-of-function variants, identified through exome sequencing, single-nucleotide polymorphism array-based homozygosity mapping, and international collaboration. The evaluated all presented MVID. Eight also...
To investigate whether vaccination against SARS-CoV-2 is associated with the onset of retinal vascular occlusive disease (RVOD).In this multicentre study, data from patients central and branch vein occlusion (CRVO BRVO), artery (CRAO BRAO), anterior ischaemic optic neuropathy (AION) were retrospectively collected during a 2-month index period (1 June-31 July 2021) according to defined protocol. The relation any previous was documented for consecutive case series. Numbers RVOD COVID-19...
Zusammenfassung Hintergrund Die DMEK hat sich als Goldstandard zur Therapie endothelial bedingter Hornhautdekompensationen in den letzten Jahren durchgesetzt. schnelle postoperative Visusbesserung und die im Vergleich perforierenden Keratoplastik niedrigere Abstoßungsrate bei diesem minimal-invasiven Verfahren begründen hohe Akzeptanz der DMEK. Fragestellung Ziel dieser Studie war es, durch das Erfassen von patienten- transplantatabhängigen Einflussgrößen Rahmenbedingungen für ein optimales...
Hintergrund: Histologische Veränderungen von Kollagen und extrazellulärer Matrix wurden nach lokaler Applikation ProstaglandinF2 α(PGF2 α)-Analoga beschrieben. Vor diesem Hintergrund untersuchten wir den Einfluss PGF2 α auf die zentrale Hornhautdicke. Patienten Methoden: In einer nicht randomisierten, kontrollierten Querschnittsstudie 403 Augen 208 konsekutiven untersucht: 149 Normalprobanden/gesunde Kontrollaugen, 79 mit okulärer Hypertension (OHT), 119 primärem Offenwinkelglaukom (POWG) 56...
Electrochemotherapy (ECT) enhances responsiveness to cytotoxic drugs in numerous cell lines vitro.Clinically ECT is widely applied for skin tumor ablation and has shown effi cacy treating non-resectable colorectal liver metastases.Th ere limited experience of ocular therapy.We investigated the eff ect bleomycin cisplatin combination with electroporation on chemoresistant human uveal melanoma (UM) vitro.Four UM (Mel 270, 92-1, OMM-1, OMM-2.5) were treated (pulse amplitude 300-1000 V/cm, 8-80...
Acanthameoba keratitis is a serious ophthalmological condition with potentially vision‐threatening prognosis. Early diagnosis and recognition of relapse, the detection persistent Acanthamoeba cysts, are essential for informing prognosis managing condition. We suggest use in vivo confocal microscopy not only to identify early signs relapse after keratoplasty patients keratitis, but also as an additional follow‐up tool antimicrobial crosslinking. This study shows that is, experienced hands,...