A5022558573- Gestational Diabetes Research and Management
- Bariatric Surgery and Outcomes
- Diabetes Treatment and Management
- Cardiac Valve Diseases and Treatments
- Liver Disease Diagnosis and Treatment
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Obesity and Health Practices
- Diet, Metabolism, and Disease
- Cardiac and Coronary Surgery Techniques
- Antimicrobial Resistance in Staphylococcus
- Infective Endocarditis Diagnosis and Management
- Metabolism, Diabetes, and Cancer
- Pancreatitis Pathology and Treatment
- Dermatology and Skin Diseases
- Birth, Development, and Health
- Parathyroid Disorders and Treatments
- Mechanical Circulatory Support Devices
- Aortic Disease and Treatment Approaches
- Exercise and Physiological Responses
- Cardiac Structural Anomalies and Repair
- Stress Responses and Cortisol
- Dietary Effects on Health
- Diet and metabolism studies
- Eating Disorders and Behaviors
- Cardiac, Anesthesia and Surgical Outcomes
Gentofte Hospital
2008-2025
Steno Diabetes Centers
2020-2025
Herlev Hospital
2023-2025
Copenhagen University Hospital
2025
University of Copenhagen
2008-2023
Danish Diabetes Academy
2016-2020
Odense University Hospital
2016-2020
German Center for Diabetes Research
2017
Rigshospitalet
2009
Type 2 diabetes increases the risk of nonalcoholic fatty liver disease (NAFLD), which is a potentially reversible condition but also associated with progressive fibrosis and cirrhosis. Women prior gestational mellitus (pGDM) have higher for NAFLD.One hundred women without who had pGDM (median [interquartile range]: age 38.6 [6.4] years; BMI 31.0 [6.2] kg/m2) 11 healthy control subjects NAFLD (age 37.9 [7.8] 28.1 [0.8] underwent 75-g oral glucose tolerance test (OGTT), DXA whole-body scan,...
Introduction The global prevalence of people living with overweight has tripled since 1975 and more than 40% Danish women enter pregnancy being overweight. With the increasing rates obesity observed in children, adolescents adults, there is an urgent need for preventive measures. Risk factors childhood include maternal or before conception excessive weight gain during pregnancy. Interventions aimed at modifying lifestyle have demonstrated minimal positive no impact on health children....
Introduction Gestational diabetes mellitus (GDM) poses health risks due to hyperglycaemia, which can lead clinical complications for mother and child. While dietary therapy serves as first-line treatment, approximately one-third of women with GDM require insulin obtain glycaemic control. However, amplifies hospital care expenses personal burdens. Intensive nutrition education, training support may improve intake leading control reducing the need therapy. This study investigates effectiveness...
Prior gestational diabetes mellitus (pGDM) is associated with increased risk of nonalcoholic fatty liver disease (NAFLD). Treatment glucagon-like peptide 1 (GLP-1) receptor agonists has shown beneficial effects in NAFLD patients. We evaluated the effect GLP-1 analogue liraglutide on features women pGDM. Eighty-two overweight/obese, nondiabetic pGDM were included. performed abdominal ultrasound, transient elastography controlled attenuation parameter (CAP), and blood sampling at baseline...
We investigated the effect of 52-week treatment with liraglutide, a glucagon-like peptide 1 receptor agonist, on glucose tolerance and incretin in women previous gestational diabetes mellitus (pGDM).Women overweight/obesity pGDM were randomized to once daily subcutaneous liraglutide 1.8 mg or placebo for 52 weeks. Participants underwent oral test (OGTT) isoglycaemic intravenous infusion at baseline weeks, an additional OGTT after drug wash-out.In total, 104 [age: mean ± SD, 38 5 years;...
Objective: Respiratory failure is a major complication after cardiac surgery. The purpose was to evaluate the impact of minimally invasive aortic valve replacement (mini AVR) on occurrence left lower lobe atelectasis (LLLA) in intensive care unit (ICU). Patients and Methods: 98 patients were scheduled undergo mini AVR. 14 these converted full sternotomy due technical problems. These compared group 50 having planned AVR through sternotomy. incidence LLLA evaluated first postoperative chest...
Pregnancy is associated with decreased insulin sensitivity, which usually overcome by a compensatory increase in secretion. Some pregnant women are not able to their secretion sufficiently, and consequently develop gestational diabetes mellitus (GDM). The disease normally disappears after delivery. Nevertheless, previous GDM have high risk of developing type 2 (T2D) later life. We aim investigate the early development T2D evaluate whether treatment glucagon-like peptide-1 receptor (GLP-1R)...
Gestational diabetes mellitus (GDM) has been associated with reduced postprandial glucagon-like peptide 1 (GLP-1) responses. As pregnancy induces changes in gallbladder motility and bile acids stimulate GLP-1 secretion, we investigated emptying responses women GDM.
The objective of the study was to evaluate results treatment severe aortic endocarditis with an homograft (an valve and root from a donor) in combination antibiotic therapy. 24 patients either prosthetic (n=16) or native (n=8) destruction 1 more cusps, paravalvular abscess formation and/or cardiac fistulas caused by aggressive bacteria, underwent surgery 1997-2006. Staphylococcal species were most common pathogens followed streptococci. Intravenous therapy started before continued for at...
Metabolic effects of intermittent unhealthy lifestyle in young adults are poorly studied. We investigated the gluco-metabolic and hepatic participation Roskilde Festival (1 week binge drinking junk food consumption) young, healthy males.Fourteen festival participants (FP) were studied before, during after 1 week's Festival. Fourteen matched controls (CTRL) who did not participate or change their other ways along a similar timeline.The FP group consumed more alcohol compared to standard...
To examine whether adults with mild to moderate atopic dermatitis (AD) had reduced insulin sensitivity and/or exhibited other gluco-metabolic disturbances compared carefully matched healthy controls.Sixteen adult, non-obese, non-diabetic patients AD and 16 gender-, age- body mass index (BMI)-matched controls underwent a hyperinsulinaemic euglycaemic clamp (insulin infusion rate: 40 mU/m2 /minute) an oral glucose tolerance test (OGTT) frequent blood sampling for gut pancreatic hormones.The...
Women with prior gestational diabetes mellitus (pGDM) are at high risk of developing type 2 (T2D). We evaluated whether treatment the glucagon-like peptide-1 receptor agonist, liraglutide, for 5 years reduces T2D in these women. Overweight women pGDM were randomized to an active arm (treatment liraglutide 1.8 mg once-daily years) or a control (placebo 1 year and thereafter no treatment) (Table). At baseline, one five years, 4-hour 75 g-oral glucose tolerance test (OGTT) intravenous...
Polycystic ovary syndrome (PCOS) is associated with insulin resistance (IR) and a high risk of type 2 diabetes. We investigated the incretin effect (IE) gastrointestinal-mediated glucose disposal (GIGD) in lean women PCOS IR, but normal fasting plasma glucose, whether metformin affects IE GIGD these women. Ten normoglucose-tolerant, IR (homeostatic model assessment (HOMA-IR) > 1.5) were randomly allocated to receive (500 mg bid) or placebo for 12 weeks interposed by 6-week wash-out...