A5039624202- Bioactive natural compounds
- Essential Oils and Antimicrobial Activity
- Sirtuins and Resveratrol in Medicine
- Phytochemicals and Antioxidant Activities
- Plant biochemistry and biosynthesis
- Natural Compound Pharmacology Studies
- Alkaloids: synthesis and pharmacology
- Traditional and Medicinal Uses of Annonaceae
- Microbial Natural Products and Biosynthesis
- Biological and pharmacological studies of plants
- Natural product bioactivities and synthesis
- Fungal Biology and Applications
- Medicinal Plants and Neuroprotection
- GABA and Rice Research
- Analytical Chemistry and Chromatography
- Crystallization and Solubility Studies
- Ethnobotanical and Medicinal Plants Studies
- African Botany and Ecology Studies
- Phytochemistry and Bioactivity Studies
- Berberine and alkaloids research
- Phytochemistry and Bioactive Compounds
- Biochemical and biochemical processes
- Synthetic Organic Chemistry Methods
- Phytochemicals and Medicinal Plants
- Medicinal Plant Research
Universiti Teknologi MARA
2014-2024
National University of Malaysia
2013
Calotropis procera (family Apocynaceae) is a valuable medicinal plant as it contains many phytochemicals such glycosides (mostly cardenolides), flavonoids, triterpenes, alkaloids, steroids, saponins, proteins and enzymes. Multiparous biological activities anti-inflammatory, antioxidant, anticancer, wound healing wideranging antimicrobial of C. have been well investigated reported. The main aim this review was to present the encompassing information regarding latex, different crude extracts...
Identification of chemical composition essential oils as raw materials is very important for ensuring the quality finished herbal products. The objectives study were to determine leaves three Cinnamomum species (i.e. mollissimum Hook.f., porrectum (Roxb.) Kosterm. and verum J.S. Presl.) characterise constituents by using GC multivariate data analysis. Hydro-distilled evaluated GC–FID GC–MS techniques. chromatograms further analysed analysis principal component (PCA) hierarchical clustering...
This study aimed to isolate and characterise purified compound from the root of Sesbania grandiflora. The grandifloraprovided a new natural compound:l,l’-binaphthalene-2,2’-diol (1) together with two known isoflavanoids (2-3). Complete 1H- 13C-NMR data compounds isolated were reported. structures determined through various spectroscopic methods notably 1D- 2D-NMR, UV, IR HRESIMS.
Abstract Four new oligostilbenes, including one dimer and three tetramers of resveratrol, that is, heimiols B–E ( 1 – 4 ) were isolated from the heartwood Neobalanocarpus heimii (Dipterocarpaceae), together with thirteen known resveratrol oligomers 5 17 ). Examination structural diversity oligostilbenes led to hypothesis their biogenetic origin through a small number versatile chemical pathways. These hypotheses are strongly supported by computational calculations (based on density...
Svalbardines A and B (1 2) annularin K (3) were isolated from cultures of Poaceicola sp. E1PB, an endophyte the petals Papaver dahlianum Svalbard, Norway. Svalbardine (1) is a pyrano[3,2-c]chromen-4-one, new analogue citromycetin. (2) displays unprecedented carbon skeleton based on 5′-benzyl-spiro[chroman-3,7′-isochromene]-4,8′-dione core. Annularin hydroxylated derivative D. The structure these polyketides, along with those known compounds 4–6, was established by spectrometric analysis,...
Two new diterpene pyrones, asperginols A (1) and B (2), four known analogues (3–6) were isolated from the endophytic fungus Aspergillus sp. HAB10R12. The structures absolute configurations of these compounds elucidated based on analysis their NMR, MS, X-ray diffraction data. revision at C-10, C-11, C-14 pyrones determination configuration polyene side chain for (4–6) made using chemical methods vibrational circular dichroism analysis. This group pyrone showed unique structural features...
Hibiscus sabdariffa L., belonging to the Malvaceae family, has been long used as herbal medicine, food, beverage, flavouring, and colouring agents. This study aims review document evidence regarding potential use of H. ethnomedicine in some countries its bioactive constituents therapeutic properties. The electronic databases were search for relevant information this up March 2022. high usage traditional medicine is due easy accessibility low price. plant often treat intestinal problems,...
Medium pressure liquid chromatography and semipreparative high-performance chromatography, followed by recycling were used for the isolation purif...
Withania somnifera belongs to the family of Solanaceae. It is widely used by locals, especially in India, as a medicinal plant. W. rich alkaloid and steroidal lactone that account for various pharmacological activities. The present study aimed review all evidence on ethnobotanical perspective some countries. This also analyses bioactive compounds online medical literature databases such ScienceDirect, PubMed, Google Scholar were search articles up March 2022. Asian African countries like...
Sixteen compounds of Neobalanocarpus heimii were successfully identified directly from their plant extract using a triple quadrupole LC-MS/MS system. In order to fulfil the objectives this work, series stilbene oligomers various degrees condensation isolated and structure are characterized. Out these, four resveratrol dimers, three trimers, nine tetramers. The isolation process was done on fully automated semi-preparative HPLC Their structures elucidated basis 1D- 2D-NMR as well MS data....
A liquid chromatography mass spectrometry (LC-MS) system was used to identify and distinguish oligostilbene diastereoisomers. polyphenolic extract from Neobalanocarpus heimii known be rich in oligostilbenes of various degrees condensation as test material. Fourteen were isolated this on a fully automated semi-prepar-ative HPLC system. Out these, two pairs dimers, one pair trimers, tetramers group four with similar skeleton identified Their structures configurations established by...
Our previous studies on Malaysian Uncaria (Rubiaceae) have yielded over 20 compounds including alkaloids and flavonoids with some showing interesting biological activities.In the search of new bioactive from genus, a phytochemical investigation lanosa (Wall.)locally known as "gegambir paya" or hitam" was carried out via metabolite profiling.The plant is reported to be used an infusion for intestine inflammation decoction cleaning wounds ulcers.Metabolite profiling using ultrahigh-performance...
A method for compound identification based on mass fragmentation patterns was developed to distinguish known oligostilbenes directly in crude plant extracts. Eleven pure were used as standard compounds, and a pilot database of MS data established. Seven extracts from Dipterocarpaceous plants; three Neobalanocarpus heimii, Dryobalanops spp. one Dipterocarpus semivestitus test materials. compounds positively identified the heartwood extract, nine bark, six leaves each lanceolata, D. rappa...
Three oligostilbenes have been identified in stems extract of Dipterocarpus semivestitus through dereplication strategy. The was injected to liquid chromatography tandem mass spectroscopy. Two tetramer, hopeaphenol and hemsleyanol D, were by comparing their fragmentation patterns with in-house library. A trimer, a-viniferin isolated various separation techniques its structure confirmed NMR analyses comparison published data.