- Layered Double Hydroxides Synthesis and Applications
- Magnesium Oxide Properties and Applications
- Supercapacitor Materials and Fabrication
- Advanced Photocatalysis Techniques
- Inorganic Chemistry and Materials
- Polyoxometalates: Synthesis and Applications
- Mesoporous Materials and Catalysis
- Advancements in Battery Materials
- Graphene and Nanomaterials Applications
- Nanoparticles: synthesis and applications
- Nanomaterials for catalytic reactions
- Polymer Surface Interaction Studies
- Advanced Battery Materials and Technologies
- Catalytic Processes in Materials Science
- Clay minerals and soil interactions
- MXene and MAX Phase Materials
- Bone Tissue Engineering Materials
- Microplastics and Plastic Pollution
- Nanoparticle-Based Drug Delivery
- Graphene research and applications
- biodegradable polymer synthesis and properties
- Synthesis and properties of polymers
- Advanced battery technologies research
- Adsorption and biosorption for pollutant removal
- Advanced Polymer Synthesis and Characterization
Dongguk University
2019-2025
National Cancer Center
2023
Seoul Institute
2019-2020
Yonsei University
2010-2019
Government of the Republic of Korea
2017-2019
Korea Institute of Geoscience and Mineral Resources
2009-2014
Osaka University
2014
Inha University
2014
National Institute of Advanced Industrial Science and Technology
2014
Shizuoka University
2014
Background: This study explored the pharmacokinetics, tissue distribution, and excretion profile of zinc oxide (ZnO) nanoparticles with respect to their particle size in rats. Methods: Two ZnO different (20 nm 70 nm) were orally administered male female rats, respectively. The area under plasma concentration-time curve, excretion, fate organs analyzed. Results: concentration both sizes increased during 24 hours after administration a dose-dependent manner. They mainly distributed such as...
We present the mechanism for cellular uptake of layered double hydroxide (LDH) nanoparticles that are internalized into MNNG/HOS cells principally via clathrin-mediated endocytosis. The intracellular LDHs highly colocalized with not only typical endocytic proteins, such as clathrin heavy chain, dynamin, and eps15, but also transferrin, a marker process, suggesting their specific internalization pathway. loaded an anticancer drug (MTX−LDH) were prepared to confirm efficacy delivery systems....
In this feature article, the applications of layered nanomaterials as green materials are demonstrated along with their structures and properties. Due to unique 2-dimensional biocompatibility, various eco- bio-friendly can be hybridized nanoparticles such double hydroxides (LDHs), hydroxy salts (HDSs) cationic clays. From small molecules drugs, herbicides, fertilizers, food ingredients large substances like deoxyribonucelotides (DNA), protein, enzymes, functional incorporated into via...
Abstract The surface of layered double hydroxide nanoparticles, a potential drug‐delivery nanovehicle, is modified with the cancer‐cell‐specific ligand, folic acid. modification successfully accomplished through step‐by‐step coupling reactions aminopropyltriethoxysilane and 1‐ethyl‐3‐(3‐dimethyl aminopropyl)‐carbodiimide. In order to evaluate cancer‐cell targeting effect folic‐acid‐grafted utilizing fluorescence‐related assay, both without acid moiety are labeled fluorescein...
Abstract Layered double hydroxides (LDHs) are biocompatible materials which can be used as drug‐delivery nanovehicles. In order to define the optimum size of LDH nanoparticles for efficient cellular uptake and pathway, we prepared different sized with narrow distribution by modulating crystal growth rate, labelled each particle a fluorophore using silane coupling reaction. The rate LDHs was found highly dependent on (50>200≥100>350 nm), whose range 50 200 nm selectively internalized...
While development of a sodium-ion battery (SIB) cathode has been approached by various routes, research on compatible anodes for advanced SIB systems not sufficiently addressed. The anode materials based titanium oxide typically show low electrical performances in primarily due to their electrical/ionic conductivity. Thus, this work, layered oxides were hybridized with covalent organic nanosheets (CONs), which exhibited excellent conductivity, be used as SIBs. Moreover, enlarge the...
A CON are hybridized with layered SnS 2 to improve electrical conductivity and structural stability of for lithium ion battery systems. Therefore, the hybrid shows outstanding performances over 5600 charge/discharge cycles.
In this highlight, the emerging new discipline of nanotoxicology is discussed in terms nanomedicine, nanocosmetics, and nanofood. particular, a wide variety applications inorganic layered double hydroxide (LDH) nanoparticles multidisciplinary fields their potential toxicity compared to that other nanoparticlesin vitro as well vivo are described detail. Study on can provide critical information about practical biological applications, finally contributing sustainable development...
A methotrexate (MTX)-layered double hydroxide (LDH) hybrid have been developed as a drug delivery system, in which an anticancer drug, MTX, was intercalated into 2-dimensional LDH nanovehicle to form nanohybrid. According the comparative cell viability studies between MTX only and its nanohybrid on sensitive resistant culture lines, it found that MTX-LDH could bypass resistance eventually inhibit cancer proliferation very effectively compared free due enhanced permeability retention effect...
Immunotoxicity of titanium dioxide nanoparticles via simultaneous induction apoptosis and multiple toll-like receptors signaling through ROS-dependent SAPK/JNK p38 MAPK activation Madhusmita Dhupal,1,2 Jae-Min Oh,3 Dipti Ranjan Tripathy,4 Soo-Ki Kim,2 Sang Baek Koh,5 Kyu-Sang Park6 1Department Global Medical Science, Wonju College Medicine, Yonsei University, Wonju, Republic Korea; 2Department Microbiology, 3Department Chemistry Chemistry, Science Technology, 4Department Neurology, Gauhati...