A5101987520- Muscle Physiology and Disorders
- Amyotrophic Lateral Sclerosis Research
- Shoulder Injury and Treatment
- Pain Mechanisms and Treatments
- Extracellular vesicles in disease
- Musculoskeletal pain and rehabilitation
- Muscle metabolism and nutrition
- Vagus Nerve Stimulation Research
- Muscle activation and electromyography studies
- Nerve injury and regeneration
- Medical Imaging and Analysis
- Musculoskeletal synovial abnormalities and treatments
- Polysaccharides and Plant Cell Walls
- 3D Printing in Biomedical Research
- Mesenchymal stem cell research
- Periodontal Regeneration and Treatments
- Spine and Intervertebral Disc Pathology
- Neuroscience of respiration and sleep
- Cancer Treatment and Pharmacology
- Neurogenetic and Muscular Disorders Research
- Histone Deacetylase Inhibitors Research
- Hip disorders and treatments
- Plant-Microbe Interactions and Immunity
- Sleep and Wakefulness Research
- Adipose Tissue and Metabolism
University of Georgia
2024-2025
Sun Yat-sen University
2017-2021
Sun Yat-sen Memorial Hospital
2017-2021
ORCID
2020
Abstract The apoplast is a critical interface in plant-pathogen interactions particularly the context of pattern-triggered immunity (PTI), which initiated by recognition microbe-associated molecular patterns (PAMPs). Our study characterizes proteomic profile Arabidopsis during PTI induced flg22, 22 amino acid bacterial flagellin epitope, to elucidate output PTI. Apoplastic washing fluid (AWF) was extracted with minimal cytoplasmic contamination for LC-MS/MS analysis. We observed consistent...
Amyotrophic lateral sclerosis (ALS) is a devastating neuromuscular disease characterized by progressive motor neuron degeneration and muscle atrophy, with no effective treatments available. Chronic inflammation, which impairs regeneration promotes proteolysis, key contributor to ALS-related atrophy promising therapeutic target. Here, we applied extracellular vesicles (EVs) derived from regenerating skeletal muscles 14 days post-acute injury (CTXD14SkM-EVs), possess unique anti-inflammatory...
Amyotrophic lateral sclerosis (ALS) is a devastating neuromuscular disease characterized by progressive motor neuron degeneration and muscle atrophy, with no effective treatments available. Chronic inflammation, which impairs regeneration promotes proteolysis, key contributor to ALS-related atrophy promising therapeutic target. Here, we applied extracellular vesicles (EVs) derived from regenerating skeletal muscles 14 days post-acute injury (CTXD14SkM-EVs), possess unique anti-inflammatory...
Background . The purpose of this study is to investigate the influence transverses abdominis and lumbar multifidus thickness activation electromyogram signal characteristics after core stability training monitored by rehabilitative ultrasound imaging surface electromyogram. Methods 60 healthy volunteers were allocated randomly into two groups, one which received monitoring other participated identical without monitoring. Ultrasound image collected at 0, 4, 8 weeks during training. muscle...
The incidence of bortezomib-induced neuropathic pain hampers the progress therapy for neoplasia and also negatively affects quality life patients. However, molecular mechanism underlying remains unknown. In this study, we found that application bortezomib significantly increased expression GATA-binding protein 3 (GATA3) in spinal dorsal horn, intrathecal administration GATA3 siRNA attenuated mechanical allodynia. Furthermore, chromatin immunoprecipitation sequencing showed treatment induced...
Muscle strength is a crucial metric for assessing motor function, with significant diagnostic and prognostic value. It widely used in clinical preclinical studies as phenotypic indicator. In mouse models of neuromuscular disorders, grip provides direct, repeatable measure function changes throughout disease progression. Hindlimbs are critical evaluative targets research due to their relevancy rodent functions, but remains challenge. Existing methods, such the wire-hanging test, vivo...
Abstract Objectives: Intra-articular application of platelet-rich plasma (PRP) are found to effectively improve knee function in patients with Knee osteoarthritis (KOA). This study is identify the factors that influence effect PRP treatment KOA. Methods: was performed a rich-leukocyte autologous conditioned (ACP) system 82 who were diagnosed A Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) used score level KOA by 3 features as evaluation indicator therapeutic effect....