- Prostate Cancer Treatment and Research
- Prostate Cancer Diagnosis and Treatment
- Urologic and reproductive health conditions
- Radiomics and Machine Learning in Medical Imaging
- Liver Disease Diagnosis and Treatment
- Esophageal Cancer Research and Treatment
- Gastric Cancer Management and Outcomes
- Lung Cancer Diagnosis and Treatment
- Radiopharmaceutical Chemistry and Applications
- Diet, Metabolism, and Disease
- Intestinal Malrotation and Obstruction Disorders
- Esophageal and GI Pathology
- Cancer, Lipids, and Metabolism
- Pancreatitis Pathology and Treatment
- Gastrointestinal disorders and treatments
- Liver Diseases and Immunity
- Pancreatic and Hepatic Oncology Research
- Renal cell carcinoma treatment
- Colorectal Cancer Screening and Detection
- Peptidase Inhibition and Analysis
- Medical Imaging and Pathology Studies
- Colorectal Cancer Surgical Treatments
- Cardiovascular Function and Risk Factors
- Liver Disease and Transplantation
- Medical Imaging Techniques and Applications
Pacific Radiology (New Zealand)
2021-2024
Peter MacCallum Cancer Centre
2024
St Vincent's Hospital
2022-2023
The University of Melbourne
2022-2023
St Vincent's Health
2023
Middlemore Hospital
2019
Western General Hospital
2011
St Thomas' Hospital
2011
King's College London
2011
Type 2 diabetes is an established risk factor for development of hepatic steatosis and nonalcoholic fatty liver disease (NAFLD). We aimed to determine the prevalence clinical correlates these conditions in a large cohort people with type diabetes.A total 939 participants, aged 61-76 years, from Edinburgh Diabetes Study (ET2DS)-a large, randomly selected population diabetes-underwent ultrasonography. Ultrasound gradings were compared magnetic resonance spectroscopy subgroup. NAFLD was defined...
The PRIMARY score is a 5-category scale developed to identify clinically significant intraprostate malignancy (csPCa) on <sup>68</sup>Ga-prostate-specific membrane antigen (PSMA)–11 PET/CT (<sup>68</sup>Ga-PSMA PET) using combination of anatomic site, pattern, and intensity. Developed within the trial, requires evaluation in external datasets. This study aimed assess reproducibility diagnostic accuracy cohort patients who underwent multiparametric MRI (mpMRI) <sup>68</sup>Ga-PSMA PET before...
Background and objectiveMultiparametric magnetic resonance imaging (mpMRI) of the prostate is used for cancer diagnosis. However, mpMRI has lower sensitivity small tumours. Prostate-specific membrane antigen positron emission tomography/computed tomography (PSMA-PET/CT) offers increased over conventional imaging. This study aims to determine whether diagnostic accuracy 18F-DCFPyL PSMA-PET/CT was superior that detecting (PCa) at biopsy.MethodsBetween 2020 2021, a prospective multicentre...
With increasing use of PSMA PET/CT in the staging and restaging prostate cancer (PCa), identification non-prostate tumours (NPCaT) has become an clinical dilemma. Atypical presentations expression NPCaT are not well established. Understanding normal abnormal distribution is essential preparing clinically relevant reports guiding multidisciplinary discussion decisions.Retrospective review 1445 consecutive 18F-DCFPyL studies by experienced radiologists nuclear medicine physicians. Lesions...
Abstract Introduction Clinical and biochemical assessment biopsies can miss clinically significant prostate cancers (csPCa) in up to 20% of patients diagnose insignificant tumours leading overtreatment. This retrospective study analyses the accuracy 18 F‐DCFPyL PET/CT detecting csPCa as a primary diagnostic tool directly compares it with mpMRI treatment‐naive patients. The two modalities are then correlated determine whether they better combination, than either alone. Methods is...
To assess the correlation of pathological radical prostatectomy (RP) specimen features and prostate-specific antigen (PSA) characteristics to imaging findings on subsequent 18 F-DCFPyL positron emission tomography/computed tomography (PET/CT) in patients with biochemical failure (BF).Retrospective analysis combined PET/CT database from centres Australia New Zealand was performed. A total 205 presenting BF after RP were included this study. Imaging recorded correlated PSA at original...
Introduction Prostate-specific membrane antigen positron emission tomography (PSMA-PET) has emerged as valuable imaging to assessing metastatic disease in prostate malignancy. However, there been limited studies exploring the utility PSMA-PET primary for index lesions prior biopsy. The objective of this study is compare diagnostic accuracy 18-fluorine PSMA (18F DCFPyL PSMA) PET scans multiparametric MRI (mpMRI) detect cancer at Methods and analysis PEDAL trial a multicentre, prospective,...
We evaluated the incidence and potential etiology of tracheobronchial uptake in patients being by <sup>18</sup>F-DCFPyL PET/CT for prostate cancer (PCa). <b>Methods:</b> The study included a consecutive 100 PCa referred PET/CT. scans were retrospectively reviewed. presence or absence physiologic on was recorded. To further evaluate tracheal prostate-specific membrane antigen (PSMA) expression, immunohistochemistry performed samples taken from 2 men who had surgical resection lung cancer....
Abstract Introduction There is no consensus as to the most optimal bowel preparation regime for Computed Tomographic Colonography ( CTC ). Concerns regarding laxative LBP ) include tolerability, adverse effects and complexity of regimen. Two hospitals in Auckland changed from standard Gastrografin GG 2015. The aim this study retrospectively assess objective subjective quality measures these different preparations. Methods groups were selected patients who underwent at two September‐October...
69 Background: We hypothesized that CRM size affect survival and local recurrence for OC GOJ cancer. also assessed the utility of CT in predicting margin status. Methods: A retrospective analysis a prospective database was carried out on all patients who had esophagectomy between January 2000 July 2008. Patients diagnosed with tumors final pathologic examination were included. Distance from by specialist upper GI pathologist. Two radiologists, blinded to postoperative status, reviewed...
You have accessJournal of UrologyCME1 May 2022PD41-11 UPDATE FROM THE PEDAL TRIAL: A PROSPECTIVE SINGLE ARM PAIRED COMPARISON OF ABILITY TO DIAGNOSE AND LOCATE PROSTATE CANCER BETWEEN MULTIPARAMETRIC MRI 18F-PSMA-PET/CT Vy Tran, Thomas Sutherland, Kim Taubman, Su-Faye Lee, Daniel Lenaghan, Niall Corcoran, Nathan Lawrentschuk, Henry Woo, Lisa Tarlinton, Tim Spelman, Lauren Thomas, Russell Booth, Elisa Perry, Justin Hegarty, and Lih-Ming Wong TranVy Tran More articles by this author ,...
Abstract Purpose Prostate cancer (PCa) imaging has been revolutionized by Positron emission tomography (PET) tracers targeted to prostate specific membrane antigen (PSMA). Identification and characterization of non-PCa tumors become an increasing clinical dilemma with growing use. The primary aim this retrospective multicenter analysis was determine atypical PSMA expression in PCa aid providing clinically relevant reports guiding multidisciplinary discussion. Methods Retrospective study...