Madison T. Little

ORCID: 0000-0003-1654-737X
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About
Contact & Profiles
Research Areas
  • Adolescent Sexual and Reproductive Health
  • Intimate Partner and Family Violence
  • Ethics in Clinical Research
  • Cardiovascular Effects of Exercise
  • Cardiomyopathy and Myosin Studies
  • Poverty, Education, and Child Welfare
  • Biomedical Ethics and Regulation
  • Cellular Mechanics and Interactions
  • HIV/AIDS Research and Interventions
  • ATP Synthase and ATPases Research
  • Ethics in medical practice
  • Child Nutrition and Water Access
  • Migration, Health and Trauma
  • Sex work and related issues
  • Cardiovascular Function and Risk Factors
  • Child Abuse and Trauma
  • Homelessness and Social Issues
  • Food Security and Health in Diverse Populations
  • Mobile Health and mHealth Applications
  • S100 Proteins and Annexins
  • Genomics and Rare Diseases
  • HIV-related health complications and treatments
  • Muscle Physiology and Disorders

University of Oxford
2016-2025

Washington State University
2022-2025

Oxford Policy Management
2016-2025

Rutgers, The State University of New Jersey
2015

Abstract The government of Kenya’s Triple Threat strategy recognises the need for urgent intervention to address high incidence HIV, gender-based violence (GBV) and pregnancy among adolescent girls young women (AGYW). We used nationally representative data AGYW aged 13–24 ( n = 1344) from 2018-19 Kenya Violence Against Children & Youth Survey (VACS) in multivariable logistic regression analyses examine associations between three potential protective factors – gender-equitable attitudes,...

10.1007/s10461-025-04643-9 article EN cc-by AIDS and Behavior 2025-02-13

Every heartbeat depends on cyclical contraction-relaxation produced by the interactions between myosin-containing thick and actin-based thin filaments (TFs) arranged into a crystalline-like lattice in cardiac sarcomere. Therefore, maintenance of filament length is crucial for myocardium function. The comprised an actin backbone, regulatory troponin complex tropomyosin that controls filaments. Thin controlled tropomodulin family proteins; caps pointed ends filaments, leiomodin (Lmod) promotes...

10.1371/journal.pbio.3003027 article EN cc-by PLoS Biology 2025-01-30

Lesotho's government has shown consistent efforts to implement social protection programmes. However, while recent evidence established a positive causal relationship between some of these programmes and food security there is little on the extent which initiatives are associated with better educational sexual reproductive health outcomes among vulnerable adolescents in Lesotho.

10.1186/s12889-024-18903-1 article EN cc-by BMC Public Health 2024-06-06

Abstract A transient increase in Ca 2+ concentration sarcomeres is essential for their proper function. drives striated muscle contraction via binding to the troponin complex of thin filament activate its interaction with myosin thick filament. In addition complex, light chain and myosin‐binding protein C were also found be sensitive. However, effects on function tropomodulin family proteins involved regulating formation have not yet been studied. Leiomodin, a member family, an actin...

10.1002/pro.4358 article EN cc-by-nc Protein Science 2022-06-20
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