A5054597589- Micro and Nano Robotics
- Algal biology and biofuel production
- Microfluidic and Bio-sensing Technologies
- Force Microscopy Techniques and Applications
- Polymer Surface Interaction Studies
- Cephalopods and Marine Biology
- Molecular Communication and Nanonetworks
- Biomimetic flight and propulsion mechanisms
- Lipid Membrane Structure and Behavior
- Cellular Mechanics and Interactions
- Photoreceptor and optogenetics research
- Tribology and Wear Analysis
- Antimicrobial Peptides and Activities
- Bacterial biofilms and quorum sensing
- Aquatic Invertebrate Ecology and Behavior
- Innovative Microfluidic and Catalytic Techniques Innovation
- Neurobiology and Insect Physiology Research
- Orbital Angular Momentum in Optics
- Antimicrobial agents and applications
- Pickering emulsions and particle stabilization
- Nanoplatforms for cancer theranostics
- Lubricants and Their Additives
- Block Copolymer Self-Assembly
- Spaceflight effects on biology
- Nanofabrication and Lithography Techniques
Max Planck Institute for Dynamics and Self-Organization
2017-2024
The Scarborough Hospital
2020-2022
University of Toronto
2020-2022
Toronto Public Health
2020
Gesellschaft für wissenschaftliche Datenverarbeitung mbH Göttingen
2019
University of Göttingen
2018
Saarland University
2012
Microorganisms, such as bacteria and microalgae, often live in habitats consisting of a liquid phase plethora interfaces. The precise ways which these motile microbes behave their confined environment remain unclear. Using experiments Brownian dynamics simulations, we study the motility single Chlamydomonas microalga an isolated microhabitat with controlled geometric properties. We demonstrate how geometry habitat controls cell's navigation confinement. probability finding cell swimming near...
Abstract The rising threat of antimicrobial resistance is a crisis global scale. If not addressed, it can lead to health care system problems worldwide. This warrants alternative therapeutic approaches whose mechanism action starkly differs from conventional antibiotic‐based therapies. Here, multifunctional and stimuli‐responsive (NIR laser‐activated) platform engineered by combining the intrinsic photothermal capability excellent biocompatibility polydopamine nanoparticles (PdNPs), with...
The initial stages of biofilm formation at a surface are triggered by the association individual microorganisms. biological mechanisms and interfacial interactions underlying microbial adhesion to surfaces have been widely studied for bacteria, while microalgae remained rather unconsidered despite their technological relevance, e.g., in photo-bioreactors. We performed vivo micropipette force measurements with model organism Chlamydomonas reinhardtii, unicellular eukaryotic microalga that...
Flagella and cilia are cellular appendages that inherit essential functions of microbial life including sensing navigating the environment. In order to propel a swimming microorganism they displace surrounding fluid by means periodic motions, while precisely timed modulations their beating patterns enable cell steer towards or away from specific locations. Characterizing dynamic forces, however, is challenging typically relies on indirect experimental approaches. Here, we present direct in...
Controlling the interface between bacteria and solid materials has become an important task in biomedical science. For a fundamental comprehensive understanding of adhesion it is necessary to seek quantitative information about involved interactions. Most studies concentrate on modification surface (chemical composition, hydrophobicity, or topography) neglecting, however, influence bulk material, which always contributes overall interaction via van der Waals forces. In this study, we applied...
Quantitative imaging correlates high-resolution structure and nanomechanics of the biofilm interface.
<italic>Dictyostelium discoideum</italic>cells rely on two different mechanisms for adhesion: wetting through conventional colloidal forces and stochastic nanocluster dynamics.
Flagella and cilia are cellular appendages that inherit essential functions of microbial life including sensing navigating the environment. In order to propel a swimming microorganism they displace surrounding fluid by means periodic motions, while precisely-timed modulations their beating patterns enable cell steer towards or away from specific locations. Characterizing dynamic forces, however, is challenging typically relies on indirect experimental approaches. Here, we present direct in...
Abstract Auditory receptors can be motile to actively amplify their mechanical input. Here we describe a novel and different type of motility that, residing in supporting cells, shapes physiological responses mechanoreceptor cells. In Drosophila larvae, cap cells transmit stimuli proprioceptive chordotonal neurons. We found that the are strongly pre-stretched at rest twice relaxed length. The tension these is modulated by non-muscle myosin-II motors. Activating motors optogenetically causes...
Polyserotonin nanoparticles (PSeNP) and films are bioinspired nanomaterials that have potential in biomedical applications surface coatings. As studies on polyserotonin (PSe) still their infancy, synthetic pathways material development for this new class of nanomaterial await investigation. Here, we sought to determine how different buffers used during the polymerization serotonin form impact physicochemical properties PSe materials. We show buffer components incorporated into polymer...