A5068056623- Pancreatic and Hepatic Oncology Research
- Gallbladder and Bile Duct Disorders
- Cancer Genomics and Diagnostics
- Pancreatitis Pathology and Treatment
- Gastrointestinal Tumor Research and Treatment
- Pediatric Hepatobiliary Diseases and Treatments
- Gastrointestinal disorders and treatments
- Gastric Cancer Management and Outcomes
- Biliary and Gastrointestinal Fistulas
- Esophageal and GI Pathology
- BRCA gene mutations in cancer
- Neuroendocrine Tumor Research Advances
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Ovarian cancer diagnosis and treatment
- Lung Cancer Research Studies
- Signaling Pathways in Disease
- Colorectal Cancer Screening and Detection
- Radiomics and Machine Learning in Medical Imaging
- Tumors and Oncological Cases
- Cancer-related Molecular Pathways
- Renal cell carcinoma treatment
- Renal and related cancers
- Urinary and Genital Oncology Studies
- Cancer Cells and Metastasis
Kitasato University
2018-2024
National Sagamihara Hospital
2024
Kitasato University Hospital
2019
The aim of this study is to estimate the cutoff length for stereomicroscopically visible white core (SVWC) required pathological diagnosis subepithelial lesions (SELs) from samples obtained using a novel 22-G Franseen biopsy needle and determine sensitivity SVWC length.Thirty patients with SELs requiring diagnoses were included. EUS-guided fine-needle biopsies (EUS-FNBs) performed 22G needle. lengths measured sample isolation processing by stereomicroscopy (SIPS). utility calculated was...
Abstract REV7 is a multifunctional protein implicated in various biological processes, including DNA damage response. expression human cancer cells affects their sensitivity to DNA‐damaging agents. In the present study, we investigated significance of pancreatic ductal adenocarcinoma (PDAC). was immunohistochemically examined 92 resected PDAC specimens and 60 endoscopic ultrasound‐guided fine‐needle aspiration biopsy (EUS‐FNAB) unresectable treated with platinum‐based chemotherapy, its...
Sample isolation processing by stereomicroscopy (SIPS) was recently introduced as an alternative to rapid on-site cytologic evaluation and showed high accuracy for use in pathologic diagnoses. SIPS is a useful, but slightly complicated procedure; therefore, new, more straightforward method the objective estimation of core tissue amount required during sampling desirable. We evaluated usefulness automated multiband imaging system (AMUS) calculating whitish amounts EUS-FNA biopsy (EUS-FNAB)...
To validate endoscopic ultrasound-guided tissue acquisition (EUS-TA) used in conjunction with stereomicroscopic on-site evaluation (SOSE) as a preoperative diagnostic tool for resectable pancreatic cancer (R-PC) and borderline PC (BR-PC).
Recently, artificial intelligence (AI) has been applied to clinical diagnosis. Although AI already developed for gastrointestinal (GI) tract endoscopy, few studies have endoscopic ultrasound (EUS) images. In this study, we used a computer-assisted diagnosis (CAD) system with deep learning analysis of EUS images (EUS-CAD) and assessed its ability differentiate GI stromal tumors (GISTs) from other mesenchymal their risk classification performance.
BACKGROUNDPost-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis (PEP) is new onset acute after ERCP.This complication sometimes fatal.As such, PEP should be diagnosed early so that therapeutic interventions can carried out.Serum lipase (s-Lip) useful for diagnosing pancreatitis.However, its usefulness has not been sufficiently investigated. AIMThis study aimed to retrospectively examine the of s-Lip diagnosis PEP.
A schwannoma is a tumor originating from Schwann cells. It occasionally observed in the abdominal viscera form of submucosal derived gastric or duodenal muscularis propria. To date, only few studies have reported on pancreatic schwannomas. Furthermore, very patients are preoperatively diagnosed with because lack established imaging characteristics distinguishing this type other conditions. We herein report first English publication which surgery was avoided pathological diagnosis made solely...
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We evaluated the usefulness of a newly developed system with which total amount whitish cores in endoscopic ultrasound-guided fine-needle aspiration biopsy (EUS-FNAB) samples is automatically calculated (automated multiband imaging [AMUS]).From 30 prospectively enrolled patients suspected having pancreatic cancer, four EUS-FNAB specimens per patient were obtained. Following AMUS calculations, two prepared after stereomicroscopy-guided manual division into and reddish sections (isolation...
EUS-guided hepaticogastrostomy (EUS-HGS) is sometimes performed as re-intervention in patients who have transpapillary biliary stent dysfunction associated with conditions such gastric outlet obstruction. We describe a 92-year-old man whom covered self-expanding metal (SEMS) had been placed because of distal obstruction caused by unresectable duodenal papilla cancer. The tumor invaded the portion duodenum, causing food retention and recurrent cholangitis due to duodenobiliary reflux....
We herein report the first case of metastatic pancreatic leiomyosarcoma derived from urinary bladder diagnosed by an endoscopic ultrasound-guided fine-needle biopsy (EUS-FNB) in a 65-year-old woman. The patient had undergone total cystectomy for leiomyosarcoma. Four years thereafter, nodule was observed her left lung on chest computed tomography. Suspecting primary cancer, pulmonologists at our hospital recommended thoracoscopic biopsy, which refused. Five post-cystectomy, fluorodeoxyglucose...
ABSTRACT Background and Aim No prospective studies have verified the incidence of cholecystitis in patients using covered self‐expandable metallic stent. In this study, we aimed to investigate its risk factors after low axial force stent placement for malignant distal biliary obstruction. Methods This multicenter study included diagnosed with unresectable obstruction between November 2019 October 2022 who underwent placement. Results The technical success 93 analyzed was 100% clinical 98.9%....
Abstract Background Information on whether a fine‐needle biopsy (FNB) needle can improve histopathological specimen quality or the amount of core tissue collected in diagnosis subepithelial lesions (SELs) remains insufficient. In this study, we aimed to compare procedure outcomes and adequacy specimens aspiration (FNA) FNB needles endoscopic ultrasound‐guided acquisition (EUS‐TA) using sample isolation processing by stereomicroscopy (SIPS) patients with SELs. Methods We performed...
The concept of BRCAness has been proposed as a homologous recombination repair dysfunction triggered by genetic defect in the BRCA pathway including BRCA1/2 mutations. A certain number pancreatic ductal adenocarcinoma (PDAC) patients have BRCAness. However, large-scale analysis PDAC not performed. In addition, no basic studies examined significance cell lines.Ninety-two who underwent surgery for were enrolled. Formalin-fixed and paraffin-embedded specimens resected PDACs used to analyze...
The patient was a 46-year-old woman. CT and MRI revealed mass, 10-mm in diameter, located the uncinate process of pancreas. qualitative diagnosis difficult. On contrast-enhanced harmonic endoscopic ultrasonography (CH-EUS) , papillary solid region tumor showed contrast enhancement similar to that surrounding normal pancreatic parenchyma early phase. with an anechoic clearly depicted. A pseudopapillary neoplasm pancreas (SPN) suspected, pylorus-preserving pancreatoduodenectomy performed....
Chronic pancreatitis was diagnosed in a 69-year-old man with epigastric pain, who referred to our hospital. Computed tomography revealed stone the pancreatic head, accompanied by dilatation of main ducts body and tail. Transpapillary stenting attempted relieve pain. However, guidewire could not be advanced into tail because severe duct stenosis. Stenting abandoned, endoscopic ultrasound-guided drainage (EUS-PD) performed. Subsequently, duodenum rendezvous technique via EUS-PD route....