A5060999689- Liver Disease Diagnosis and Treatment
- Liver physiology and pathology
- Alcohol Consumption and Health Effects
- Genomics, phytochemicals, and oxidative stress
- Pharmacological Effects of Natural Compounds
- Peroxisome Proliferator-Activated Receptors
- Plant-based Medicinal Research
- Phytochemistry and Biological Activities
- Natural product bioactivities and synthesis
- Autophagy in Disease and Therapy
- Diet, Metabolism, and Disease
- MicroRNA in disease regulation
- Endoplasmic Reticulum Stress and Disease
- NF-κB Signaling Pathways
- Phytochemistry and biological activity of medicinal plants
- Rheumatoid Arthritis Research and Therapies
- COVID-19 Impact on Reproduction
- Lipid metabolism and biosynthesis
- Biochemical effects in animals
- Cannabis and Cannabinoid Research
- Organ Transplantation Techniques and Outcomes
- Sirtuins and Resveratrol in Medicine
- Natural Compounds in Disease Treatment
- Advances in Cucurbitaceae Research
- Tea Polyphenols and Effects
Chengdu University of Traditional Chinese Medicine
2020-2023
Ministry of Education of the People's Republic of China
2022-2023
Southwestern Institute of Physics
2021-2022
Alcoholic liver disease (ALD) is a multifaceted process that involves excessive lipid, reactive oxygen species (ROS) production, unbalanced mitochondrial homeostasis, and ultimate cell death. Quercetin dietary phytochemical presented in various fruits vegetables, which has anti-inflammatory antioxidant effects. According to recent advances pharmanutritional management, the effects of quercetin on processes have attracted attention. In study, we explored whether could attenuate...
Acute lung injury (ALI) is a disease characterized by inflammation and still requires further drug development. Forsythiaside A as the active compound of Forsythiae Fructus has therapeutic potential for ALI.
Exosomes are extracellular vesicles with the diameter of 30 ~ 150 nm, and widely involved in intercellular communication, disease diagnosis drug delivery carriers for targeted therapy. Therapeutic application exosomes as is limited due to lack sources methods obtaining adequate exosomes. Milk contains abundant exosomes, several studies have shown that milk-derived play crucial roles preventing treating intestinal diseases. In this review, we summarized biogenesis, secretion structure,...
Hepatic stellate cells (HSCs) activation is an important step in the process of hepatic fibrosis. NOX4 and reactive oxygen species expressed HSCs play role liver Forsythiaside A (FA), a phenylethanoid glycoside extracted isolated from Forsythiae Fructus, has significant antioxidant activities. However, it not clear whether FA can inhibiting through regulating NOX4/ROS pathway. Therefore, our purpose to explore effect mechanism on alleviate LX2 were activated by TGF-β1 vitro. MTT assay Wound...
Abstract: Quercetin is the main dietary flavonoid with a wide range of pharmacological activities. However, poor gastrointestinal absorption and low bioavailability quercetin curtails its clinical applications.. Enhancement focuses on application delivery systems technologies such as microparticle systems, solid dispersions, encapsulation, phospholipid complexes, hydrogels , which have been systematically reviewed .And theirapplications in vitro vivo animal experiments also described,...
In the prescription of Traditional Chinese Medicine for lipid metabolism, Polygoni Multiflori Radix Preparata (ZhiHeShouWu, RPMP) was widely used. recent years, RPMP ethanol extract has been reported treatment non-alcoholic fatty liver disease (NAFLD). However, role in NAFLD not fully elucidated. Therefore, we examined optimal therapeutic dose extracts. Afterward, a mouse model induced by high-fat diet (HFD) treated with to further evaluate mechanism action treatment. And serum metabolism...
Thrombosis is a general pathological phenomenon during severe disturbances to homeostasis, which plays an essential role in cardiovascular and cerebrovascular diseases. Leonurine (LEO), isolated from Leonurus japonicus Houtt, showes crucial anticoagulation vasodilatation. However, the properties therapeutic mechanisms of this effect have not yet been systematically elucidated. Therefore, antithrombotic LEO was investigated study. Hematoxylin-Eosin staining used detect thrombosis zebrafish...