- Drug-Induced Hepatotoxicity and Protection
- Antibiotics Pharmacokinetics and Efficacy
- Helicobacter pylori-related gastroenterology studies
- Electrochemical Analysis and Applications
- Drug Transport and Resistance Mechanisms
- Pharmacological Effects of Natural Compounds
- Trace Elements in Health
- Electrochemical sensors and biosensors
- Selenium in Biological Systems
- Pomegranate: compositions and health benefits
- Healthcare and Venom Research
- Pesticide Residue Analysis and Safety
- Cynara cardunculus studies
- Analytical Methods in Pharmaceuticals
- Nigella sativa pharmacological applications
- Bee Products Chemical Analysis
- Complementary and Alternative Medicine Studies
- Photoreceptor and optogenetics research
- Saffron Plant Research Studies
- Liver physiology and pathology
- Metabolism and Genetic Disorders
- Environmental Toxicology and Ecotoxicology
- Phytochemical and Pharmacological Studies
- Pharmacogenetics and Drug Metabolism
- Acute Kidney Injury Research
Atatürk University
2015-2025
Université Libre de Bruxelles
2000
Gentamicin is commonly used against gram-negative microorganisms. Its therapeutic use mainly limited by nephrotoxicity. This study was aimed at evaluating the effect of rutin on oxidative stress, inflammation, apoptosis, and autophagy in gentamicin-induced nephrotoxicity rats. The rats were treated with saline intraperitoneally (group I), 150 mg/kg orally II), 80 gentamicin for 8 d III), or plus IV). serum urea, creatinine, kidney malondialdehyde (MDA), reduced glutathione (GSH) levels...
The development and characterization of a highly sensitive enzyme immobilized carbon based electrode for the determination subnanomolar concentrations hydrogen peroxide in aqueous samples is described. biosensor consists horseradish peroxidase (HRP) solid paste along with suitable redox mediator. latter allows acceleration electroreduction HRP presence peroxide. Several phenothiazines as mediators are investigated comparative manner respect to dimethylferrocene using cyclic voltammetry...
Summary The aim of the present study was to define whether Vitis vinifera L. cv. Merlot seed extract (VVE), has a regulatory effect against gentamicin (GM) induced nephrotoxicity in broilers. Two hundred and forty broilers were divided into 4 groups, with 6 replications 10 birds each: Group I Control (C) received standard basal diet only. II administered 100Â mg/kg feed/day VVE from day 8 42. III injected daily GM (50Â body weight i.m.) for consecutive days starting at age. IV 42
<title>Abstract</title> <italic>Muscari</italic> Mill. is used raw and cooked for gastric diseases, expectorants, wart treatment, urine enhancers. No scientific study has been found on the effect of <italic>Muscari neglectum</italic> (MN) water extract stomach diseases. Here, MN plant some biochemical histopathological parameters indomethacin-induced ulcer in rats was examined. In this study, 60 male Sprague Dawley were 24 acute toxicity 36 models (n = 6). They divided into 6 groups as...
Background and Objectives: The plant Muscari Mill. is employed in both raw cooked forms for the treatment of gastric diseases, as an expectorant, warts enhancement urine. A review scientific literature revealed no studies investigating effect neglectum (MN) water extract on diseases. objective this study was to determine a MN indomethacin-induced ulcer rats, using series biochemical (SOD, CAT, GSH MDA levels) histopathological parameters. Methods: 60 male Sprague Dawley rats were utilized...
Ratlarda parasetamol ile
 oluşturulan hepatotoksisite üzerine Taraxacum
 officinale etanol ekstraktının kan ve karaciğer dokusundaki bazı
 biyokimyasal parametrelere dokusunun histopatolojisi etkileri
 araştırıldı. Bu çalışmada, 5 aylık yaşta 36 adet Sprague Dawley rat kullanıldı.
 ratlar rastgele her grupta 6 olacak şekilde gruba ayrıldı.
 Parasetamol (PARA) verilecek gruplardaki hayvanlar 24 saat aç bırakılıp
 ekstrakt verildikten 1 sonra 2 g/kg oral...
This experiment was conducted to evaluate the effects of dietary vitamin E (α-tocopherol acetate), organic selenium (selenomethionine) and their combination on some bioelements in tissues laying hens. Ninety-six white Lohman LSL hens aged 24 weeks were randomly divided into 4 equal groups. The groups fed with diets consisting basal diet (Control), + 250 mg/kg Vit-E (Trial-I), 0.9mg/kg Se (Trial-II) 0,9 (Trial-III), respectively. At end experiment, 12 from each group sacrificed,...