Gan L

ORCID: 0000-0003-1686-3321
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About
Contact & Profiles
Research Areas
  • Nanoparticle-Based Drug Delivery
  • Advanced Polymer Synthesis and Characterization
  • Surfactants and Colloidal Systems
  • Hydrogels: synthesis, properties, applications
  • Graphene and Nanomaterials Applications
  • RNA Interference and Gene Delivery
  • International Law and Aviation
  • Judicial and Constitutional Studies
  • Military and Defense Studies
  • China's Ethnic Minorities and Relations
  • Asian American and Pacific Histories
  • Neural Networks and Applications
  • EEG and Brain-Computer Interfaces
  • Linguistics and Cultural Studies
  • Chinese history and philosophy
  • Neural dynamics and brain function
  • biodegradable polymer synthesis and properties
  • Comics and Graphic Narratives
  • Lexicography and Language Studies
  • Swearing, Euphemism, Multilingualism

Nankai University
2009-2025

Xinjiang Normal University
2015

Poly(ethylene glycol)-block-poly(acrylic acid-co-acrylamidophenylboronic acid) [PEG114-b-(PAA63-co-PAAPBA107)] was synthesized by the modification of poly(ethylene (PEG114-b-PAA170) with 3-aminophenylboronic acid (APBA). Glucose-responsive PEG114-b-(PAA63-co-PAAPBA107) self-assembled into core−shell micelles hydrophobic core composed PAAPBA and hydrophilic shell PEG in aqueous solution. The swelling disaggregating behaviors responding to glucose were investigated using light scattering...

10.1021/la901776a article EN Langmuir 2009-10-07

Polymeric nanoparticles with glucose-responsiveness under physiological conditions are of great interests in developing drug delivery system for the treatment diabetes. Herein, glucose-responsive complex micelles were prepared by self-assembly a phenylboronic acid-contained block copolymer PEG-b-P(AA-co-APBA) and glycopolymer P(AA-co-AGA) based on covalent complexation between acid glycosyl. The formation P(AA-co-APBA)/P(AA-co-AGA) core PEG shell was confirmed HNMR analysis. investigated...

10.1021/bm3012715 article EN Biomacromolecules 2012-09-07

Herein, a series of biocompatible, robust, pH/sugar-sensitive, core-cross-linked, polyion complex (PIC) micelles based on phenylboronic acid-catechol interaction were developed for protein intracellular delivery. The rationally designed poly(ethylene glycol)-b-poly(glutamic acid-co-glutamicamidophenylboronic acid) (PEG-b-P(Glu-co-GluPBA)) and glycol)-b-poly(l-lysine-co-ε-3,4-dihydroxyphenylcarboxyl-L-lysine) (PEG-b-P(Lys-co-LysCA)) copolymers successfully synthesized self-assembled under...

10.1021/bm4007387 article EN Biomacromolecules 2013-08-20

We developed a glucose-responsive complex polymeric micelle (CPM) through the self-assembly of two types diblock copolymers, poly(ethylene glycol)-b-poly(aspartic acid-co-aspartamidophenylboronic acid) (PEG-b-P(Asp-co-AspPBA)) and poly(N-isopropylacrylamide)-b-poly(aspartic (PNIPAM-b-P(Asp-co-AspPBA)). By controlling weight ratio between PNIPAM PEG (WPNIPAM/WPEG = 6/4), block copolymers form micelles with novel core–shell–corona structure. following this structure, continuous shell collapsed...

10.1039/c2sm26690c article EN Soft Matter 2012-12-11

Brain-computer interfaces (BCI) acquire electroencephalogram (EEG) signals to effectively address postoperative motor dysfunction in stroke patients by discerning their intentions during significant movements. Traditionally, noninvasive BCIs have been constrained limitations usage environments; whereas, invasive damage neural permanently. Therefore, we proposed a novel interventional BCI, which electrodes are implanted along the veins into brain intracerebral EEG without an open craniotomy....

10.1109/tnsre.2025.3562922 article EN cc-by-nc-nd IEEE Transactions on Neural Systems and Rehabilitation Engineering 2025-01-01
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