A5077773285- Mechanical Circulatory Support Devices
- Transplantation: Methods and Outcomes
- Venous Thromboembolism Diagnosis and Management
- Atrial Fibrillation Management and Outcomes
- Cardiac Structural Anomalies and Repair
- Heart Failure Treatment and Management
- Cardiac Valve Diseases and Treatments
- Cardiac pacing and defibrillation studies
- Acute Ischemic Stroke Management
- Congenital Heart Disease Studies
- Cardiovascular Function and Risk Factors
- Viral Infections and Immunology Research
- Organ Transplantation Techniques and Outcomes
- Fuel Cells and Related Materials
- COVID-19 Clinical Research Studies
- Cardiac tumors and thrombi
- Maternal and fetal healthcare
- Diabetes Treatment and Management
- Cardiac Arrhythmias and Treatments
- Adenosine and Purinergic Signaling
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Ultrasound and Hyperthermia Applications
- Aortic aneurysm repair treatments
- Muscle and Compartmental Disorders
- Autoimmune Neurological Disorders and Treatments
Loyola University Medical Center
2017-2024
Vanderbilt University Medical Center
2022
Loyola University Chicago
2021
North Shore University Hospital
2021
Thomas Jefferson University
2019
National Institute on Drug Abuse
2016
University of Chicago
1982
Focused ultrasound with microbubbles is being developed to transiently, locally and noninvasively open the blood-brain barrier (BBB) for improved pharmaceutical delivery.Prior work has demonstrated that, a given concentration dose, microbubble size affects both intravascular circulation persistence extent of BBB opening.When matched gas volume however, half-life was found be independent size.In order determine whether this holds true opening as well, we independently measured effects (2 vs....
Pulmonary embolism (PE) is the third-leading cause of cardiovascular mortality, accounting for 100,000 deaths per year in United States. Although sex-based disparities have previously been described this population, it unclear if these differences persisted with expansion PE evaluation and treatment approaches. The purpose study to investigate evaluation, management, outcomes patients acute PE.
Purpose: The aim of this study was to determine the impact OrCam on vision-related quality life patients with legal blindness and end-stage glaucoma. is a device comprised camera earpiece attached user’s eyeglass that translates written text speech. Methods: In prospective, observational study, total 27 participants were recruited tested. All legally blind. Participants provided during period trained how operate it. National Eye Institute Visual Functioning Questionnaire-25 (NEI-VFQ-25)...
Use of left ventricular assist devices (LVADs) for management advanced heart failure is becoming increasingly common; however, device associated thrombosis remains an important cause mortality in this patient population. We hypothesize that inflammation LVAD implanted patients dysregulates the protein C pathway, creating a hypercoagulable state leading to thrombosis. Plasma samples from 22 with Thoratec HeartMate II were analyzed by commercial ELISAs. Retrospective sample selection included...
Gastrointestinal bleeding (GIB) is a common cause of morbidity among patients supported by left ventricular assist devices (LVADs). The aim this study was to identify if pre-LVAD right (RV) dysfunction associated with risk GIB after LVAD implantation. Of 398 implanted LVADs between July 2008 and 2016, 130 (33%) developed at median 2.6 months following Arteriovenous malformations (AVMs) were found in 42 (34%) patients. Patients older more likely have hypertension, diabetes, ischemic...
Risk stratification of acute pulmonary embolism (PE) is important to identify patients at risk for hemodynamic collapse who would benefit from more aggressive therapies. Angiopoietin-2 (Ang-2) a signaling molecule involved in angiogenesis and upregulated response tissue hypoxia. We aimed assess the association Ang-2 with (1) PE severity, (2) echocardiographic invasive markers right ventricular (RV) dysfunction, (3) need intensive treatment. Patients presenting our institution were included...
Current guidelines recommend against the use of hearts from donors that abuse alcohol. We explored effect donor alcohol (AA) on cardiac allograft function and outcomes in heart transplant (HTx) recipients.Overall, 370 HTx recipients were divided into two groups: (a) alcoholic group (AD, n = 58) (b) non-alcoholic (NAD, 312).Recipients AD had a slower rate (86 ± 13 vs 93 13, P 0.004) an increased incidence early atrial fibrillation (AF) (30% 11%, 0.003). Echocardiographic left ventricular mass...
Hampton hump in acute pulmonary embolismA 50-year-old woman with a medical his- tory signifi cant for childhood asthma presented to the emergency department 3-week history of worsening dyspnea and cough bilateral lower-extremity swelling, left-side swelling greater than right-side swelling.On presentation, her heart rate was 121 beats per minute, blood pressure 197/133 mm Hg, respiratory 32 breaths minute oxygen saturation 96% on room air.Physical examination notable tachycardia normal S1 S2...
Guillain-Barré syndrome (GBS) is rare autoimmune polyneuropathy that infrequently seen in the post-transplant population, presumably due to presence of immunosuppression. When it does occur this setting, Cytomegalovirus (CMV) infection a common inciting factor. Treatment modalities for GBS include intravenous immunoglobulin (IVIg) or plasmapheresis. Rarely, IVIg infusion has been associated with myocardial infarction. We describe case patient status post heart transplantation who presented...
Abstract Introduction While the global dissemination of vaccines targeting severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has resulted in a decline incidence infections, case fatality rates have remained relative stable. A major objective managing hospitalized patients with documented or suspected COVID-19 infection is rapid identification features associated illness using readily available laboratory tests and clinical tools. The sequential organ failure assessment (SOFA)...
Background: Outpatient management has been shown to be safe and effective for patients presenting the emergency department (ED) with low-risk acute pulmonary embolism (PE). The degree which outpatient PE evolved in contemporary clinical practice is uncertain, as an understanding of whether certain patient or hospital factors are associated management. Methods: Using Nationwide Emergency Department Sample, we identified hospitalizations primary secondary between 2006-2018. We excluded who...
Abstract Background Acute pulmonary embolism (PE) is associated with a high morbidity and mortality. There paucity of data describing outcomes patients PE transferred from different acute care hospital. We hypothesized that for may be suboptimal potentially as result treatment delays due to non-protocolized transfer plan this cohort patients. Methods used the Nationwide Inpatient Sample (NIS) 2008–2018 identify hospitalized primary diagnosis by using International Classification...