- Advanced Glycation End Products research
- Ocular Surface and Contact Lens
- Glaucoma and retinal disorders
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Retinopathy of Prematurity Studies
- Intraocular Surgery and Lenses
- Cerebrovascular and genetic disorders
- Barrier Structure and Function Studies
- Retinal and Macular Surgery
Soochow University
2023
Children's Hospital of Suzhou University
2023
First Affiliated Hospital of Soochow University
2023
Tianjin Medical University
2020-2022
Tianjin Medical University Eye Hospital
2020-2022
Corneal neovascularization (CNV) is a sight-threatening condition usually associated with various inflammatory settings including chemical injury. High mobility group box 1 (HMGB1) identified as an alarmin in diverse tissue damage. Here, we evaluate the expression of HMGB1 and consequences its inhibition through selective inhibitor glycyrrhizin (GLY) alkali burn-induced corneal inflammation neovascularization. GLY effectively attenuated at both mRNA protein levels. Furthermore, slit-lamp...
Purpose: Recurrent retinal detachment (re-RD) is one of the complications in rhegmatogenous patients who underwent surgical treatment. We investigated risk factors for re-RD and developed a nomogram estimating clinical risk. Methods: Univariate multivariable logistic regression models were performed to determine association between variables re-RD, was then re-RD. The performance assessed based on its discrimination, calibration, usefulness. Results: This study analyzed 15 potential 403...