A5056224435- Tendon Structure and Treatment
- Shoulder Injury and Treatment
- Sports injuries and prevention
- Knee injuries and reconstruction techniques
- Shoulder and Clavicle Injuries
- Periodontal Regeneration and Treatments
- Lower Extremity Biomechanics and Pathologies
- Orthopedic Surgery and Rehabilitation
- Polymer composites and self-healing
- Silicone and Siloxane Chemistry
- Diabetic Foot Ulcer Assessment and Management
- Synthesis and properties of polymers
- Fiber-reinforced polymer composites
- Tribology and Wear Analysis
- Advanced X-ray and CT Imaging
- Dental Implant Techniques and Outcomes
- Electrospun Nanofibers in Biomedical Applications
- Wound Healing and Treatments
- Foot and Ankle Surgery
- Polymer Nanocomposites and Properties
- Cardiac Valve Diseases and Treatments
- Total Knee Arthroplasty Outcomes
- Polymer Nanocomposite Synthesis and Irradiation
- High voltage insulation and dielectric phenomena
- Epoxy Resin Curing Processes
Wuhan Sports University
2014-2024
East China University of Science and Technology
2020
Central South University
2014-2019
Xiangya Hospital Central South University
2014-2018
Sichuan Entry-Exit Inspection and Quarantine Bureau
2015
Functional fibrocartilage regeneration is a bottleneck during bone-tendon healing, and the currently available tissue-engineering strategies for are insufficient because of lack appropriate scaffold that can load large seeding-cells induce chondrogenesis stem cells. The acellular (AFS) contains active growth factors as well tissue-specific epitopes cell-matrix interactions, which make it potential tissue-engineered fibrocartilage. A limitation to this its low porosity inhibits cells loading...
Background: Low-intensity pulsed ultrasound stimulation (LIPUS) has been proven to be a beneficial biophysical therapy for tendon-bone (T-B) healing. However, the optimal time initiate LIPUS treatment not determined yet. initiated at different stages of inflammatory phase may profoundly affect T-B Purpose: An established rabbit model was used preliminarily investigate effect initiation timing on Study Design: Controlled laboratory study. Methods: A total 112 mature rabbits that underwent...
Abstract: Ultra-high molecular weight polyethylene (UHMWPE)/epoxy composites with excellent adhesive properties were prepared by forming an interface membrane on the UHMWPE fiber surface. The of and epoxy resin was polymerized aldol condensation between polyvinyl alcohol (PVA) glutaraldehyde. Different surface treatment methods fibers optimized two-step PVA-glutaraldehyde (Corona-PG-2S) method is best. interfacial adhesion enhanced, composite improved. X-ray photoelectron spectroscopy (XPS)...
Tendon-bone interface (TBI) injuries are common in sports activities. Owing to the limited regenerative ability of TBI, its functional healing remains a difficulty clinical practice. Icariin (ICA) provides strong stimulation for osteogenesis. Platelet-rich plasma (PRP) can be used as carrier bioactive molecules, although provide sustained release such molecules needs improvement.Freeze-dried PRP (FD-PRP) ICA into tendon-bone (T-B) site, thus accelerating T-B healing.Controlled laboratory...
Mechanical stimulation and platelet-rich plasma (PRP) have been shown to be beneficial for healing of the bone-tendon interface (BTI), but few studies explored efficacy a combination these applications. We investigated effect mechanical combined with PRP on rotator cuff repair in mice.Mechanical can enhance BTI murine model repair.Controlled laboratory study.A total 160 C57BL/6 mice were used. Overall, 40 used prepare PRP, while 120 underwent acute supraspinatus tendon (SST) repair. The...
Abstract Purpose The current biomechanical research on the application of Kinesio taping (KT) to patients with chronic ankle instability (CAI) has focused testing expected movements. However, unexpected movements are more common in actual sports. Therefore, present study aimed investigate effects KT characteristics knee and joints during jumping Methods Twenty‐one unilateral CAI were recruited capture parameters under different interventions: no (NT), placebo (PT), KT. A one‐way repeated...
This study was designed to evaluate the effects of low-intensity pulsed ultrasound on bone regeneration during bone–tendon junction healing process and explore application synchrotron radiation micro computed tomography in three dimensional visualization microarchitecture new trabecular bone. Twenty four mature New Zealand rabbits underwent partial patellectomy establish a injury model at patella–patellar tendon complex. Animals were then divided into treatment (20 min/day, 7 times/week)...
At the tendon-to-bone insertion, there is a unique transitional structure: tendon, non-calcified fibrocartilage, calcified and bone. The reconstruction of this special graded structure after defects or damage an important but challenging task in orthopedics. In particular, fibrocartilage zone has yet to be successfully achieved. study, development novel book-shape scaffold derived from extracellular matrix was reported. Specifically, pubic symphysis obtained rabbits sliced into shape book...
Background: A limb symmetry index (LSI) of >90% for single-leg horizontal hop distance is recommended as a cutoff point safe return to sports after anterior cruciate ligament reconstruction (ACLR). Despite achieving this threshold, abnormal lower biomechanics continue persist in athletes ACLR. Symmetry vertical height appears be more difficult achieve and can better representation knee function than distance. Purpose: To explore whether an LSI represent normal during bilateral jump Study...
Understanding the three-dimensional ultrastructure morphology of tendon-to-bone interface may allow development effective therapeutic interventions for enhanced healing. This study aims to assess feasibility propagation phase-contrast synchrotron radiation microtomography (PPC-SRµCT) characterization microstructure in rabbit patella–patellar tendon (PPTI). Based on phase retrieval PPC-SRµCT imaging, this technique is capable visualizing internal architecture PPTI at a cellular high spatial...
Platelet-rich plasma (PRP) is widely used clinically to treat tendon injuries, and often contains leukocytes. However, the debate regarding concentration of leukocytes in PRP still ongoing. This study aimed evaluate therapeutic effects leukocyte-rich platelet-rich (LR-PRP) leukocyte-poor (LP-PRP) on healing bone-tendon interface (BTI) rotator cuff. A total 102 C57BL/6 mice were used. Thirty prepare PRP, while 72 underwent acute supraspinatus injury repair. The animals then randomly assigned...
Tendon attaches to bone through a functionally graded fibrocartilage zone, including uncalcified (UF), tidemark (TM) and calcified (CF). This transition zone plays pivotal role in relaxing load transfer between tendon bone, serves as boundary otherwise structurally distinct tissue types. Calcium zinc are believed play important roles the normal growth, mineralization, repair of bone–tendon junction (BTJ). However, spatial distributions calcium at BTJ their distribution–function relationship...
Background: After anterior cruciate ligament reconstruction (ACLR), single-leg horizontal hop distance limb symmetry index (LSI) >90% is recommended as a cutoff point for safe return to sport (RTS). However, athletes after ACLR have abnormal lower biomechanics despite an adequate LSI, implying that are at high risk of reinjury. Symmetry vertical jump height appears be more difficult achieve and can better representation knee function than distance. Hypothesis: Athletes with LSI had...
Background: Platelet-rich plasma (PRP) has demonstrated beneficial effects on healing of the bone-tendon interface (BTI). Purpose: To determine optimal initiation time for PRP application after rotator cuff repair in an animal model. Study Design: Controlled laboratory study. Methods: A total 136 C57BL/6 mice were included; 40 used to prepare PRP, while 96 underwent acute supraspinatus tendon (SST) repair. The animals randomly divided into 4 groups: a control group and 3 groups which was...
The nano-particle modified epoxy resin adhesive was prepared by adding different types of nanoparticles to the adhesives.The influence kinds and amount on mechanical properties investigated.The investigation results indicated that addition three including nano-silica,nano-titanium dioxide,nano zinc oxide has a significant nano-composites.And tensile strength breaking elongation nano-composites reached maximum when nanoparticle 4wt%.In addition,the toughening mechanisms nano-particles...
Many orthopedic surgical procedures involve reattachment between tendon and bone. Whether bone–tendon healing is better facilitated by fixation on a bone surface or within tunnel unknown. The purpose of this study was to comparatively evaluate the effects versus trough in rabbit patella–patellar (PPT) injury model. rabbits underwent partial patellectomy with patellar-tendon osteotomy (bone fixation, BSF group) (n = 28) BTF 28). PPT interface evaluated macroscopic observation, micro-computed...
The waterborne polyurethane/nano-silica composites (WPU/nano-silica, WPUS) and WPU modified by polyethersiloxanediol (WPUPES) were prepared, respectively. properties of WPUS WPUPES investigated various characterizations. results showed both had better waterproof property thermal stability than neat WPU. However, has a lower elongation at break due to the higher micro-phase separation. This is ascribed migration aggregation siloxane segments during film formation. tensile strength was that...