Login

M. Morbidelli

ORCID: 0000-0003-1727-1715
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
A5116675719
Research Areas
  • Inhalation and Respiratory Drug Delivery
  • Analytical Chemistry and Chromatography
  • Surfactants and Colloidal Systems

University of Padua
 2025

 Species differences in opsonization and phagocyte recognition of preclinical poly-2-alkyl-2-oxazoline-coated nanoparticles
OPENALEX - Publications 
Regina Tavano Lucía Morillas-Becerril Alessandra Geffner-Smith G. Ronzani R. Gervasutti and 18 more Giorgio Arrigoni Ilaria Battisti M. Morbidelli Patrizia Polverino de Laureto Luana Palazzi Alda Natale Eliana Schiavon Patrizio Coin Edmondo M. Benetti Matteo Romio Francisco Corzana Ester Jiménez‐Moreno Mattia Sturlese Giovanni Bolcato Stefano Moro S. Moein Moghimi Fabrizio Mancin Emanuele Papini

Poly(ethylene glycol) (PEG) is widely used in nanomedicine design, but emerging PEG immunogenicity the general population of therapeutic concern. As alternative, polyoxazolines are gaining popularity, since "polyoxazolinated" nanoparticles show long-circulating properties comparable to PEGylated mice. Here, we species differences opsonization and differential uptake by monocytes macrophages coated with either poly-2-methyl-2-oxazoline or poly-2-ethyl-2-oxazoline. These evade murine process...

10.1038/s41467-025-57648-2 article EN cc-by-nc-nd Nature Communications 2025-03-18
Coming Soon ...