A5073392367- Nanoparticles: synthesis and applications
- Gold and Silver Nanoparticles Synthesis and Applications
- Nanoparticle-Based Drug Delivery
- Advanced Nanomaterials in Catalysis
- Laser-Ablation Synthesis of Nanoparticles
- Wound Healing and Treatments
- Skin Protection and Aging
- Graphene and Nanomaterials Applications
- Microplastics and Plastic Pollution
- Spectroscopy and Chemometric Analyses
- Medical and Biological Ozone Research
- Light effects on plants
- Bacterial biofilms and quorum sensing
- Near-Field Optical Microscopy
- thermodynamics and calorimetric analyses
- Drug Transport and Resistance Mechanisms
- Surfactants and Colloidal Systems
- Cancer Research and Treatment
- Cellular Mechanics and Interactions
- Advancements in Transdermal Drug Delivery
- Mesenchymal stem cell research
- Cholesterol and Lipid Metabolism
- Advanced Biosensing Techniques and Applications
- Lipid Membrane Structure and Behavior
- 3D Printing in Biomedical Research
Stony Brook University
2011-2021
State University of New York
2012-2021
Gold nanoparticles (AuNPs) are used in many applications; however, their interactions with cells and potential health risk(s) not fully known. In this manuscript, we describe the of AuNPs human dermal fibroblasts show that they can penetrate plasma membrane accumulate large vacuoles. We also demonstrate uptake is a function time, size concentration. Specifically, 45 nm via clathrin-mediated endocytosis, while smaller 13 enter mostly phagocytosis. Furthermore, provide evidence cytoskeleton...
Titanium dioxide (TiO2) is one of the most common nanoparticles found in industry ranging from food additives to energy generation. Approximately four million tons TiO2 particles are produced worldwide each year with approximately 3000 being nanoparticulate form, hence exposure these almost certain. Even though also used as an anti-bacterial agent combination UV, we have that, absence HeLa cells significantly increased their risk bacterial invasion. cultured 0.1 mg/ml rutile and anatase for...
Gold nanoparticles (AuNPs) are currently used in numerous medical applications. Herein, we describe their vitro impact on human adipose-derived stromal cells (ADSCs) using 13 nm and 45 citrate-coated AuNPs. In non-differentiated state, ADSCs were penetrated by the AuNPs stored vacuoles. The presence of resulted increased population doubling times, decreased cell motility cell-mediated collagen contraction. degree to which impacted was a function particle concentration, where smaller...
Compact fluorescent light (CFL) bulbs can provide the same amount of lumens as incandescent bulbs, using one quarter energy. Recently, CFL exposure was found to exacerbate existing skin conditions; however, effects on healthy tissue have not been thoroughly investigated. In this study, we studied illumination human cells (fibroblasts and keratinocytes). Cells exposed CFLs exhibited a decrease in proliferation rate, significant increase production reactive oxygen species, their ability...
Increasing production of nanomaterials requires fast and proper assessment its potential toxicity. Therefore, there is a need to develop new assays that can be performed in vitro, cost effective, allow faster screening engineered (ENMs). Herein, we report titanium dioxide (TiO2) nanoparticles (NPs) induce damage adipose derived stromal cells (ADSCs) at concentrations which are rated as safe by standard such measuring proliferation, reactive oxygen species (ROS), lactate dehydrogenase (LDH)...
In this study, we investigated experimentally the dependency of radio frequency (rf) absorption by gold nanoparticles (AuNPs) on (10 kHz to 450 MHz), NP size (3.5, 17, and 36 nm), charge ligand shell (positive amino negative carboxylic functional groups), aggregation state, presence electrolytes (0-1 M NaCl). addition, examined effect protein corona rf AuNPs. For first time, energy AuNPs was analyzed in 10 MHz range. We have demonstrated that previously reported heating can be solely...
The use of surface-enhanced Raman spectroscopy (SERS) to delineate between the breast epithelial cell lines MCF10A, SK-BR-3, and MDA-MB-231 is explored utilizing varied morphologies gold nanoparticles. nanoparticles studied had spherical, star-like, quasi-fractal (nanocaltrop) possessed varying degrees surface inhomogeneity complexity. efficacy enhancement these was a function their size, morphology, associated density "hot spots," as well cellular uptake. spherical star-like provided strong...
The synthesis of star-like gold nanoparticles (SGNs) in a temperature-controlled environment allows for temperature modulation and facilitates the growth highly branched nanoparticles. By increasing temperature, level branching increases as well. These features represent distinctly novel, quasi-fractal nanoparticle morphology, referred to herein nano caltrops (GNC). increased surface roughness, local curvature degree inhomogeneity GNC lend themselves generating improved enhancement...
This research describes a new method of aqueous synthesis gold nanoparticles in the presence cetyltrimethylammonium bromide and folic acid through seed-mediated growth approach. These have shape similar to corals, therefore, we referred them as 'gold nanocorals' (AuNCs). Specifically, AuNCs consist solid core surrounded densely by branches. The branches exhibit nanosized roughness that creates multiple plasmonic hot-spots increase AuNCs' SERS activity. In this study, demonstrated at fast...
Quasi-fractal gold nanoparticles can be synthesized via a modified and temperature controlled procedure initially used for the synthesis of star-like nanoparticles. The surface features leads to improved enhancement Raman scattering intensity analyte molecules due increased number sharp possessing numerous localized plasmon resonances (LSPR). LSPR is affected by size shape as well inter-nanoparticle interactions, these affect oscillation modes electrons on nanoparticle surfaces. effect...
<p>Quasi-fractal gold nanoparticles can be synthesized via a modified and temperature controlled procedure initially used for the synthesis of star-like nanoparticles. The surface features leads to improved enhancement Raman scattering intensity analyte molecules due increased number sharp possessing numerous localized plasmon resonances (LSPR). LSPR is affected by size shape as well inter-nanoparticle interactions, these affect oscillation modes electrons on nanoparticle surfaces....
Investigation of cultured skin cells have been conducted by a terahertz scanning reflectometer. In particular, the dermal fibroblasts alone and same treated with titanium nanoparticles examined for their thickness profile.