A5089041665- Cardiac Arrhythmias and Treatments
- Atrial Fibrillation Management and Outcomes
- Cardiac electrophysiology and arrhythmias
- Cardiac pacing and defibrillation studies
- Congenital Heart Disease Studies
- Mechanical Circulatory Support Devices
- Cardiac Arrest and Resuscitation
- Tracheal and airway disorders
- Cardiac Valve Diseases and Treatments
- Cardiac, Anesthesia and Surgical Outcomes
- Airway Management and Intubation Techniques
- Coronary Artery Anomalies
- Cardiac Structural Anomalies and Repair
- Child and Adolescent Health
- Sports injuries and prevention
- Intensive Care Unit Cognitive Disorders
- ECG Monitoring and Analysis
- Central Venous Catheters and Hemodialysis
- Family and Patient Care in Intensive Care Units
- Cardiovascular Conditions and Treatments
- Venous Thromboembolism Diagnosis and Management
- Blood transfusion and management
- Cardiovascular Issues in Pregnancy
- Cardiovascular Syncope and Autonomic Disorders
- Acute Kidney Injury Research
ZNA Middelheim Hospital
2012-2025
Emory University
2013-2024
AZ Sint-Jan
2015-2024
Children's Healthcare of Atlanta
2012-2023
Vanderbilt University Medical Center
2023
Ziekenhuisnetwerk Antwerpen Stuivenberg
2022-2023
Michigan State University
2023
Université de Bordeaux
2017-2020
Hôpital Cardiologique du Haut-Lévêque
2017-2019
Electrophysiology and Heart Modeling Institute
2018-2019
We have recently shown that a contact force (CF)-guided ablation protocol respecting region-specific criteria of lesion contiguity and depth ('CLOSE' protocol) is associated with high incidence acute durable pulmonary vein (PV) isolation (PVI) single-procedure arrhythmia-free survival at 1 year. In the present study, we compared efficiency, safety, efficacy 'CLOSE'-guided PVI to conventional CF-guided (CONV-CF).Fifty consecutive paroxysmal atrial fibrillation (AF) patients underwent PV...
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Background— Pulmonary vein reconnection (PVR) still determines recurrences of atrial fibrillation after contact force (CF)–guided pulmonary isolation. We studied whether acute PVR (adenosine and waiting time) late (at repeat) are explained by incomplete transmurality contiguity within the deployed radiofrequency circle. Methods Results— analyzed 42 CF-guided ipsilateral isolation procedures. For each tag circle, we collected data reflecting lesion depth (time application, power, impedance...
Ventricular tachycardia (VT) with structural heart disease is dependent on reentry within scar regions. We set out to assess the VT circuit in greater detail than has hitherto been possible, using ultra-high-density mapping.All mapping guided ablation cases from 6 high-volume European centers were assessed. Maps analyzed offline generate activation maps of circuits. Topography, conduction velocity, and voltage complete maps.Thirty-six tachycardias 31 patients identified, 29 male 27 ischemic....
Background: Biatrial tachycardia (BiAT) is a rare form of atrial macroreentrant tachycardia, in which both atria critical part the circuit. We aimed to identify characteristics and precise circuits single-loop BiATs. Methods Results: identified 8 patients (median age, 59.5 years old) with 9 BiATs cohort 336 consecutive from 2 institutions who had undergone AT catheter ablation using an automatic ultrahigh-resolution mapping system. Seven history persistent AF ablation, including septal or...
Recently, we established an inhibitory avoidance paradigm in Tupfel Long-Fin (TL) zebrafish. Here, compared task performance of TL fish and from the AB strain; another widely used strain shown to differ genetically behaviourally fish. Whole-body cortisol telencephalic gene expression related stress, anxiety fear were measured before 2 h post-task. Inhibitory was assessed a 3-day paradigm: learn avoid swimming white black compartment where 3V-shock is given: day 1 (first shock), (second...
Background: Long-term results of substrate modification for ablation ventricular tachycardia (VT) have not been reported. We report long-term outcomes elimination targeting local abnormal activities (LAVA) post–myocardial infarction VT. Methods and Results: One hundred fifty-nine consecutive patients undergoing first were included (65±11 years, 92% implantable cardioverter defibrillators, 54% storms, 73% appropriate shocks). LAVA identified in VT was inducible 73%. Complete noninducibility...
Background: Atrial fibrillation ablation–related atrial tachycardia (AT) is complex and may demonstrate several forms: anatomic macroreentrant AT (AMAT), non-AMAT, focal AT. We aimed to elucidate the recurrence rate mechanisms of recurrence. Methods: Among 147 patients with ATs treated Rhythmia system, 68 (46.3%) had at mean 4.2 (2.9–11.6) months, 44 received a redo procedure. circuits in first procedure were compared those Results: Although mappable not observed 7 patients, 37 during...
We hypothesized that an epicardial approach using ethanol infusion in the vein of Marshall (EIVOM) may improve result ablation for perimitral flutter (PMF).We studied 103 consecutive patients with PMF undergoing high-resolution mapping. The first 71 were treated radiofrequency (RF) alone (RF-group), and next 32 underwent EIVOM followed by RF on endocardial mitral isthmus (EIVOM/RF-group). Contact force was not measured during ablation. Acute 1-year outcomes compared. Flutter termination...
Characteristics of multiple-loop atrial tachycardia (AT) circuits have never precisely examined.In 193 consecutive post-atrial fibrillation ablation patients with AT, 44 ATs including 42 dual-loop AT and 2 triple-loop in 41 (21.2%) were diagnosed the high-resolution mapping system analyzed off-line.In ATs, 3 types identified: type M, a combination anatomic macroreentrant (AMATs) 19 (43.2%); MN, 1 AMAT non-AMAT 12 (27.3%); N non-AMATs 11 (25.0%). The remaining (4.5%) perimitral-,...
Achieving block across linear lesions is challenging. We prospectively evaluated radiofrequency (RF) ablation at the roof and mitral isthmus (MI) using point-by-point contiguous optimized RF lesions.Forty-one consecutive patients with symptomatic persistent AF underwent stepwise contact force (CF)-guided catheter during ongoing AF. A single set of was delivered posterior MI according to 'Atrial LINEar' (ALINE) criteria, i.e. delivery (up 35 W) respecting strict criteria contiguity...