A5063101480- HIV/AIDS Research and Interventions
- HIV Research and Treatment
- HIV/AIDS drug development and treatment
- HIV/AIDS Impact and Responses
- Adolescent Sexual and Reproductive Health
- HIV-related health complications and treatments
- Frailty in Older Adults
- Global Maternal and Child Health
- Health Systems, Economic Evaluations, Quality of Life
- Global Health Care Issues
- Poverty, Education, and Child Welfare
- Child Nutrition and Water Access
- Pneumocystis jirovecii pneumonia detection and treatment
- Health disparities and outcomes
- Geriatric Care and Nursing Homes
- Hepatitis B Virus Studies
- Viral gastroenteritis research and epidemiology
- Aging and Gerontology Research
- HIV, Drug Use, Sexual Risk
- Nutrition and Health in Aging
- COVID-19 epidemiological studies
- Migration, Health and Trauma
- Cytomegalovirus and herpesvirus research
- Hepatitis Viruses Studies and Epidemiology
- Salmonella and Campylobacter epidemiology
University of Rome Tor Vergata
2015-2024
Policlinico Tor Vergata
2015-2024
Catholic University Our Lady of Good Counsel
2024
Saint Camillus International University of Health and Medical Sciences
2020
Libera Università Maria SS. Assunta
1994-2020
Policlinico Umberto I
2020
Institute for Biomedicine
2019
Istituto Superiore di Sanità
2008-2018
Scuola Superiore Sant'Anna
2018
Center for Global Health
2018
Background: The Drug Resource Enhancement against AIDS and Malnutrition (DREAM) program is a large antiretroviral therapy treatment financed by the Treatment Acceleration Program (TAP) of World Bank.In addition to provision individuals infected with human immunodeficiency virus (HIV) in sub-Saharan Africa, one major aspect DREAM nutritional supplementation prevention mother-to-child transmission (PMTCT) HIV.Methods: HIV-positive pregnant women enrolled receive highly active (HAART) free...
The elderly, who suffer from multiple chronic diseases, represent a substantial proportion of Emergency Department (ED) frequent users, thus contributing to ED overcrowding, although they could benefit other health care facilities, if those were available. aim this study was evaluate and characterize hospital visits older patients (age 65 or greater) the university teaching in Rome 1st January 31st December 2014, order identify clinical social characteristics potentially associated with...
Despite advances in treatment, up to 30% of patients with early breast cancer (BC) experience distant disease relapse. However, a comprehensive understanding tumor spread and site-specific recurrence patterns remains lacking. This retrospective case-control study included 103 consecutive metastatic BC admitted our institution (2000-2013). Cases were matched according age, biology, clinicopathological features 221 non-metastatic (control group). The median follow-up period among the 324...
Extraordinary restrictions aimed to limit Sars-CoV-2 spreading; they imposed a total reorganization of the health-system. Oncological treatments experienced significant slowdown. The aim our multicentric retrospective study was evaluate screening suspension and surgical treatment delay during COVID-19 impact on breast cancer presentation.All patients who underwent surgery from March 11, 2020 May 30, were evaluated considered as Lockdown group. These compared with similar previous year,...
Background/Aim: Coronavirus disease is spreading worldwide. Due to fast transmission and high fatality rate drastic emergency restrictions were issued. During the lockdown, only urgent medical services are guaranteed. All non-urgent services, as breast cancer (BC) screening, temporarily suspended. The potential of screening programs in increasing survival decreasing mortality has been widely confirmed. Suspension could lead worse outcomes for patients. Our study aimed analyse data provide...
This study was designed to determine the role of demographic, medical and cognitive factors in results rehabilitation first stroke patients. In a prospective on 273 consecutive patients admitted hospital for sequelae stroke, we used multiple regressions assess relationship between 11 independent variables battery outcome measures: mortality, length stay, Barthel Index (BI) Rivermead Mobility (RMI) scores at discharge their effectiveness. Severity admission hemineglect were strongest...
The response to treatment and risk factors for early mortality following initiation of combination antiretrovirals (ARVs) in a cohort African patients are described retrospective design. Medical history, laboratory parameters, data were reviewed initiating ARVs 12 clinical centers Mozambique, Tanzania, Malawi. Among 3456 HIV-1-infected who received more than 6 months, at baseline 72% had WHO stages 3/4, 7% viral load <400 copies/ml, 38% CD4 cell count >200/μl. One year later, 78%...
Antiretroviral treatment programs in sub-Saharan Africa have high rates of early mortality and loss to follow-up. Switching second-line regimens is often delayed because limited access laboratory monitoring.Retrospective analysis was performed a cohort adults who initiated standard first-line antiretroviral at 5 public sector sites 3 African countries. Monitoring included routine CD4 cell counts, human immunodeficiency virus RNA measures, records whether appointments were kept. Incidence...
Reduction of HIV-1 breast-feeding transmission remains a challenge for prevention pediatric infections in Sub-Saharan Africa. Provision formula decreases but often increases child mortality this setting.A prospective observational cohort study exposed infants mothers receiving pre and postnatal medical care at Drug Resource Enhancement Against AIDS Malnutrition centers Mozambique was conducted. Live-born HIV-1-infected women were enrolled. testing performed 1, 6, 12 months age using branched...
Objective: To evaluate pregnancy outcomes in a cohort of HIV-infected women receiving triple antiretroviral therapy (ART) for prevention mother-to-child-transmission. Methods: A retrospective study with review records 3273 HIV-positive prenatal care Malawi and Mozambique from July 2005 to December 2009 was conducted Drug Resource Enhancement Against AIDS Malnutrition (DREAM) centers. Patients were offered nevirapine-based ART initiated until 6 months postpartum. Main outcome measures...
Italy was one of the first European countries affected by new coronavirus (COVID-19) pandemic, with over 105,000 infected people and close to 13,000 deaths, until March 31st. The pandemic has hit especially hard because country's demographic structure, a high percentage older adults. authors explore possibility, recently aired in some studies, extensive intergenerational contact as possible determinant severity among Italian We analyzed several variables test this hypothesis, such patients...
Tuberculosis (TB) is among the more frequent causes of death in many countries. For pulmonary TB, early diagnosis greatly increases efficiency therapies. Although highly sensitive tests based on nucleic acid amplification (NAATs) and loop-mediated isothermal (TB-LAMP) are available, smear microscopy still most widespread diagnostics method low–middle-income countries, true positive rate lower than 65%. Thus, there a need to increase performance low-cost diagnosis. years, use sensors analyze...
Nevirapine is widely used to treat HIV-1 infection prevent mother-to-child transmission; unfortunately adverse drug reactions have been reported. Our aim was identify genes/variants involved in nevirapine-induced hepatotoxicity.Patients from Mozambique, 78 with hepatotoxicity and without events, were genotyped for ABCB1, CYP2B6, CYP3A4 CYP3A5 gene variants. We conducted a case-control association study genotype/phenotype correlation analysis.The ABCB1 c.3435C>T SNP associated (p = 0.038),...
BackgroundOptimized preventive strategies are needed to reach the objective of eliminating pediatric AIDS. This study aimed define determinants residual HIV transmission in context maternal antiretroviral therapy (ART) administration pregnant women, assess infant safety this strategy, and evaluate its impact on disease. Methodology/Principal FindingsA total 311 HIV-infected women were enrolled Malawi an observational received a nevirapine-based regimen from week 25 gestation until 6 months...
OPINION article Front. Med., 30 April 2018 | https://doi.org/10.3389/fmed.2018.00123
Citation: Vanni G, Pellicciaro M, Materazzo Palombi L and Buonomo OC (2020) Breast Cancer Diagnosis in Coronavirus-Era: Alert From Italy. Front. Oncol. 10:938. doi: 10.3389/fonc.2020.00938
Osteoporosis is the most common bone disease, characterized by decreased mineral density (BMD) and often associated to muscle mass function. Metal exposure plays a role in pathophysiology of osteoporosis affects also quality. The aim this study was assess association between metal levels samples degeneration these tissues. A total 58 subjects (30 male 28 female) enrolled classified osteoporotic (OP, n = 8), osteopenic (Ope, 30) healthy (CTR, 20) subjects, according BMD measures. Femoral head...