ABSTRACT Both dogs and humans can be coinfected with various Ehrlichia , Bartonella Rickettsia Babesia species. We investigated a kennel of sick Walker Hounds their owners in southeastern North Carolina for evidence tick-borne infections associated risk factors. A high degree coinfection was documented the dog population. Of 27 dogs, 26 were seroreactive to an sp., 16 canis 25 vinsonii 22 seroconverted rickettsii antigens. According PCR results, 15 infected 9 chaffeensis 8 ewingii 3 equi...

The genus Bartonella includes fastidious, facultative intracellular bacteria mainly transmitted by arthropods and distributed among mammalian reservoirs. spp. implicated as etiological agents of zoonoses are increasing. Apart from the classical henselae, B. bacilliformis or quintana, other species (B. elizabethae, rochalimae, vinsonii arupensis v. berkhoffii, tamiae koehlerae, others) have also been associated with human and/or animal diseases. Laboratory techniques for diagnosis (culture,...

Bartonella spp. infection has been reported in association with an expanding spectrum of symptoms and lesions. Among 296 patients examined by a rheumatologist, prevalence antibodies against henselae, B. koehlerae, or vinsonii subsp. berkhoffii (185 [62%]) bacteremia (122 [41.1%]) was high. Conditions diagnosed before referral included Lyme disease (46.6%), arthralgia/arthritis (20.6%), chronic fatigue (19.6%), fibromyalgia (6.1%). henselae significantly associated prior to neurologist, most...

Few studies have examined the broad health effects of occupational exposures in flight attendants apart from disease-specific morbidity and mortality studies. We describe status compare it to U.S. population. In addition, we explore whether prevalence major conditions is associated with length exposure aircraft environment using job tenure as a proxy.We surveyed two domestic airlines 2007 compared their contemporaneous cohorts National Health Nutrition Survey (NHANES), 2005-2006 2007-2008....

Bartonella vinsonii subsp. berkhoffii is an important, emerging, intravascular bacterial pathogen that has been recently isolated from immunocompetent patients with endocarditis, arthritis, neurological disease and vasoproliferative neoplasia. Vector transmission suspected among dogs wild canines, which are the primary reservoir hosts. This investigation was initiated to determine if pets family members were infected one or more species. PCR enrichment blood culture in alpha Proteobacteria...

Canine vector-borne diseases (CVBD) are caused by a diverse array of pathogens with varying biological behaviors that result in wide spectrum clinical presentations and laboratory abnormalities. For many reasons, the diagnosis canine infectious can be challenging for clinicians. The aim present study was to compare CVBD serological molecular testing as two most common methodologies used screening healthy dogs or diagnosing sick which disease is suspected. We (Anaplasma species, Babesia...

Abstract Only indirect or circumstantial evidence has been published to support transmission of Rickettsia rickettsii by Amblyomma americanum (lone star) ticks in North America. This study provides molecular that A. can function, although most likely infrequently, as vectors Rocky Mountain spotted fever for humans.

A young woman experiencing depression, anxiety, mood swings, severe headaches, muscle spasms, interphalangeal joint stiffness, decreased peripheral vision, diminished tactile sensation, and hallucinations was persistently Bartonella koehlerae seroreactive bacteremic. Following antibiotic treatment, B. antibodies DNA were not detected all symptoms resolved.

Background: With the advent of more sensitive culture and molecular diagnostic testing modalities, Bartonella spp. infections have been documented in blood and/or cerebrospinal fluid specimens from patients with diverse neurological symptoms. Pediatric acute-onset neuropsychiatric syndrome (PANS) is characterized by an unusually abrupt onset cognitive, behavioral, or Between October 2015 January 2017, a 14-year-old boy underwent evaluation multiple specialists for sudden-onset psychotic...

Bartonella spp. are increasingly implicated in association with a spectrum of zoonotic infectious diseases. One hundred sanitary workers La Rioja, Spain, completed questionnaire and provided blood specimens for serology Alpha-Proteobacteria growth medium (BAPGM) enrichment culture/PCR. Six immunofluorescence assays (IFA) were performed aseptically obtained inoculated into liquid BAPGM subcultured onto agar plates. DNA was amplified using conventional real-time PCR assays. The spp., strain,...

Cats appear to be the primary reservoir host for Bartonella koehlerae, an alpha Proteobacteria that is most likely transmitted among cat populations by fleas (Ctenocephalides felis). koehlerae has caused endocarditis in a dog and one human patient from Israel, but other clinically relevant reports involving this bacterium are lacking. Despite publication of numerous, worldwide epidemiological studies designed determine prevalence spp. bacteremia cats, B. never been isolated using...

Abstract Background Bartonella species comprise a group of zoonotic pathogens that are usually acquired by vector transmission or animal bites scratches. Methods PCR targeting the 16S-23S intergenic spacer (ITS) region was used in conjunction with BAPGM (Bartonella alpha Proteobacteria growth medium) enrichment blood culture to determine infection status family members and amplify DNA from spiders woodlice. Antibody titers B. vinsonii subsp. berkhoffii ( Bvb ) genotypes I-III, henselae Bh...

Bartonella henselae is a zoonotic, alpha Proteobacterium, historically associated with cat scratch disease (CSD), but more recently persistent bacteremia, fever of unknown origin, arthritic and neurological disorders, bacillary angiomatosis, peliosis hepatis in immunocompromised patients. A family from the Netherlands contacted our laboratory requesting to be included research study (NCSU-IRB#1960), designed characterize spp. bacteremia people extensive arthropod or animal exposure. All four...

Bartonella species are globally important emerging pathogens that were not known to infect animals or humans in North America prior the human immunodeficiency virus (HIV) epidemic. Ongoing improvements diagnostic testing modalities have allowed for discovery of (spp.) DNA blood; cerebrospinal fluid; and skin patients with cutaneous lesions, fatigue, myalgia, neurological symptoms. We describe spp. test results participants reporting neuropsychiatric symptoms, majority whom reported...

Recently, infections with emerging zoonotic bacteria of the genus Bartonella have been reported in association a range central nervous system (CNS) symptoms. Currently, it remains unknown if spp. infection is associated symptoms schizophrenia/schizoaffective disorder (SCZ/SAD). The objective this study was to determine there an between species and SCZ/SAD. A secondary SCZ/SAD were more severe among participants documented infection. Using case–control design, 17 cases 13 controls evaluated...

After raccoons were trapped and removed from under a house in New York, the owner her two Papillon dogs became infested with numerous rat mites (Ornithonyssus bacoti). Two weeks later, both developed pruritus, progressively severe vesicular lesions, focal areas of skin exfoliation, swelling vulva or prepuce, abdominal pain, behavioral changes. months after mite infestation, was hospitalized because lethargy, fatigue, uncontrollable panic attacks, depression, headaches, chills, swollen neck...

Canine vector borne diseases (CVBDs) comprise illnesses caused by a spectrum of pathogens that are transmitted arthropod vectors. Some dogs have persistent infections without apparent clinical, hematological or biochemical abnormalities, whereas other develop acute illnesses, subclinical infections, chronic debilitating diseases. The primary objective this study was to screen healthy for serological and molecular evidence regionally important CVBDs. Clinically (n = 118), comprising three...

ABSTRACT Very recently, Bartonella organisms have been isolated from large ruminants (deer, elk, and dairy beef cattle) located in the United States France. In this study, we report serologic, microbiologic, molecular findings related to isolation of a species North Carolina cattle detection nanobacterial antigen using commercially available enzyme-linked immunosorbent assay. Between August 1998 September 1999, blood was collected 38 ranging age 1 month 6.5 years. After 1-month incubation...

The molecular characterization of a Bartonella vinsonii subsp. berkhoffii genotype III strain (NCSU 06-CO1) isolated from the blood military working dog diagnosed with endocarditis is reported in this study. Several genes were amplified and sequenced for comparative sequence similarity other strains.

Background: Controlled studies investigating risk factors for the common presenting problem of chronic cough in dogs are lacking. Hypothesis/Objectives: To identify demographic and historical associated with dogs, associations between characteristics diagnosis. Animals: Dogs were patients an academic internal medicine referral service. Coughing had a duration ≥2 months (n = 115). Control problems other than 104). Methods: Owners completed written questionnaires. Demographic information...

Background Little is known about the specificity of Bartonella spp. immunofluorescent antibody ( IFA ) assays in dogs. Bacteremia sick dogs most often has been associated with henselae Bh , vinsonii subspecies berkhoffii Bvb ), and koehlerae Bk ). Clarification diagnostic utility serology when testing against these organisms needed. Objective To evaluate utilizing 6 cell culture–grown antigen preparations. Animals Archived sera from SPF (n = 29) experimentally infected 10) 3). Methods...