A5054201008- Neonatal Health and Biochemistry
- Urological Disorders and Treatments
- Skin Diseases and Diabetes
- Autoimmune Bullous Skin Diseases
- Neonatal Respiratory Health Research
- Drug-Induced Adverse Reactions
- Autoimmune and Inflammatory Disorders
- Cardiovascular Health and Disease Prevention
- Streptococcal Infections and Treatments
- Cervical Cancer and HPV Research
- Genomics and Rare Diseases
- Reproductive tract infections research
- Pancreatic and Hepatic Oncology Research
- Cytomegalovirus and herpesvirus research
- Facial Rejuvenation and Surgery Techniques
- Cardiovascular and exercise physiology
- Cell Adhesion Molecules Research
- COVID-19 and Mental Health
- Methemoglobinemia and Tumor Lysis Syndrome
- Parvovirus B19 Infection Studies
- Cutaneous lymphoproliferative disorders research
- Healthcare Policy and Management
- Skin Protection and Aging
- Neonatal skin health care
- Oral and gingival health research
Hospital Braga
2015-2023
Centro Hospitalar de Lisboa Ocidental
2016-2023
Instituto Politécnico de Santarém
2022
Hospitais da Universidade de Coimbra
1989-2020
Instituto Politécnico de Lisboa
2012-2017
Hospital of St. Francis Xavier
2014
Centro Hospitalar de Trás os Montes e Alto Douro
2007
Coronavirus disease, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is mainly transmitted through droplets, but other ways of transmission have been hypothesized. We report a case vertical SARS-CoV-2 in preterm born to an infected mother, confirmed the presence virus neonatal blood, nasopharyngeal and oropharyngeal swabs collected first half hour life. The neonate presented with distress, similar findings severely affected adults. This highlights importance...
Abstract S tenotrophomonas maltophilia is a Gram‐negative bacillus, which an extremely rare cause of meningitis. To our knowledge, there are only five previous pediatrics cases. Here, we describe the case 4‐year‐old boy who developed meningitis associated with this organism, after several neurosurgical procedures and treatment broad‐spectrum antibiotic. He was treated successfully combination trimethoprim–sulfamethoxazole, ceftazidime levofloxacin. should be considered as potential...
Although uterine prolapse and carcinoma of the cervix are not rare events, their association is very uncommon. The treatment cervical cancer has been protocolled, but management uterovaginal associated with standardised therapy strategies vary considerably among authors. Our case reports a 74-year-old patient, admitted to emergency department an ulcerated prolapsed uterus. Biopsy lesion confirmed squamous-cell carcinoma. patient underwent vaginal hysterectomy plus open bilateral iliopelvic...
Human cytomegalovirus (HCMV) is the most frequent cause of congenital infection, leading to long-term sequelae especially sensorineural hearing loss (SNHL). Since 5-15 % asymptomatic newborns will develop late sequelae, implementation a universal screening would allow identification infected children and early intervention. The aim this study was validate use saliva pools 10 20 samples for detection HCMV infection. Four spiking (negative matrix added with known concentration AD169 strain...
Homozygous Epidermal Growth Factor Receptor (EGFR) mutation is associated with neonatal inflammatory skin and bowel disease type 2. We present the case of a preterm female infant severe growth restriction complex clinical course. She presented from birth erosive lesions as well several malformations (sparse scalp hair, craniofacial abnormalities, thin long limbs, arachnodactyly, absence subcutaneous fat, arthrogryposis congenital heart disease). developed recurrent respiratory infections,...
Pseudohypoparathyroidism (PHP) is a rare group of disorders characterised by end-organ resistance to the parathyroid hormone (PTH). A 16-year-old boy presented with 2-year history involuntary dystonic movements involving mainly left hand, initially after writing and later during physical exercise. Serum calcium was 1.37 mmol/L (2.20-2.69), phosphate 2.1 (0.8-1.45) PTH 302 ng/L (12-88). CT scan head demonstrated multiple subcortical diffuse basal ganglia calcifications. Genetic analysis...
Vaso-occlusive crises are the most common manifestation of sickle cell disease (SCD) and main cause hospital admission in these patients. There is emerging evidence that vaso-occlusive pain has both nociceptive neuropathic components. However, treatment SCD-related with drugs not yet been systematically studied, particularly children. We describe a 14-year-old girl SCD multiple admissions for management severe acute episodes. The patient was evaluated by multidisciplinary team specialists...
A 34-week-old gestational baby boy, weighing 2104 g, was born with multiple organ dysfunction and a skin rash. During pregnancy, the mother had reactive venereal disease research laboratory (VDRL) test (1:16) that didn't receive any treatment. After birth, target erythaematous maculopapular rash on child's hands soles (figures 1A, B 2) evident. He also hepatosplenomegaly, pneumonitis, anaemia (haemoglobin 11.3 g/dL), thrombocytopaenia (29 000/µL), C protein 28 mg/dL …
Introduction: Children who visit emergency departments and leave without being seen represent a multifactorial problem. We aimed to compare the sociodemographic characteristics of children left those did not leave, as well evaluate parental reasoning, subsequent use medical care patient outcome.Material Methods: This was prospective case-control study random sample their matched controls from an department during three-month period. performed phone questionnaire obtain information concerning...
Hypocalcaemia in neonates can range from asymptomatic to a potentially life-threatening condition. We present case of 36 weeks gestational age boy, admitted our neonatal intensive care unit for jitteriness, mild hypotonia and breastfeeding difficulties. By the ninth day life, he presented with late-onset hypocalcaemia, hypomagnesaemia, low 25-OH-vitamin D inappropriately normal parathyroid hormone. Further investigation revealed maternal hypercalcaemia high Maternal hyperparathyroidism was...
Imperforate hymen is the most common congenital cause of genital outflow obstruction in females, with a reported incidence 0.014–0.024% children.1 This abnormality may not be detected until onset menses, when haematocolpos causes symptoms due to expanding pelvic masses. Recurrent abdominal and back pains are symptoms, associated primary amenorrhoea urinary retention.2 ,3 A 13-year-old girl was admitted because lower …
Sweet's syndrome is a neutrophilic dermatosis of unknown etiology and rare extraintestinal manifestation ulcerative colitis. Classically, it more common in women with active inflammatory bowel disease (IBD). This typically presents patients acute-onset painful tender erythematous skin lesions usually accompanied by fever, arthralgia, elevated markers. Histological examination characterized diffuse dense dermal infiltrate leukocytoclasia, without vasculitis. The treatment goals are to reduce...
Introduction: Anemia is a common problem in preterm infants; red blood cell (RBC) transfusion the most quick and efficient treatment. The aim of this study was evaluation 2004 National Neonatal Guidelines application neonatal intensive care unit morbidity transfused or non-transfused preterm.Materials Methods:Retrospective chart review infants with birth weight (BW) ≤1500 g and/or gestational age (GA) ≤32 weeks admitted NICU between January 2010 December 2013. Patients were divided into two...
Subcapsular liver hematoma is a spontaneous bleeding between the Glisson's capsule and parenchyma. It rare but serious complication of severe preeclampsia and/or HELLP (hemolysis, elevated enzyme low platelets) syndrome that can have devastating consequences, worst being hepatic rupture with maternal death. A young nulliparous woman, at 34 weeks ‘gestation, was admitted for evaluation new onset hypertension. The pregnancy uneventful, yet 32 weeks’ gestation fetal growth restriction...
Introducao: A ventilacao nao invasiva (VNI) tem sido utilizada de forma crescente em criancas com insuficiencia respiratoria aguda (IRA), evitando as complicacoes associadas a (VI). Existem poucos dados acerca da sua utilizacao fora das unidades cuidados intensivos pediatricos (UCIP). Pretendemos descrever nossa experiencia na VNI numa Unidade Cuidados Intermedios (UCINT) e avaliar eficacia evitar transferencia para uma UCIP.Metodos: Estudo longitudinal retrospetivo todas admitidas UCINT...
An 8-year-old boy presented for evaluation of a hypopigmented halo which developed around the congenital melanocytic nevus (CMN), with one year evolution. [...]
 Received: 20/04/2017 - Accepted: 11/12/2017