A5041084071- Epilepsy research and treatment
- EEG and Brain-Computer Interfaces
- Neonatal and fetal brain pathology
- Neuroscience and Neuropharmacology Research
- Autoimmune Neurological Disorders and Treatments
- Genetics and Neurodevelopmental Disorders
- Ion channel regulation and function
- Spatial Neglect and Hemispheric Dysfunction
- Neonatal Health and Biochemistry
- Virtual Reality Applications and Impacts
- Cardiac electrophysiology and arrhythmias
- Mitochondrial Function and Pathology
- Sleep and Wakefulness Research
- Diet and metabolism studies
- Multisensory perception and integration
University Medical Center Utrecht
2017-2021
Utrecht University
2020-2021
Hospices Civils de Lyon
2020
University of Pavia
2020
Perinatal thalamic injury is associated with epilepsy electrical status epilepticus in sleep (ESES). The aim of this study was to prospectively quantify the risk ESES and assess neuroimaging predictors neurodevelopment. We included patients perinatal injury. MRI scans were obtained neonatal period, around three months age during childhood. Thalamic total brain volumes from MRI. Diffusion characteristics assessed. Sleep EEGs distinguished into (spike-wave index (SWI) >85%), ESES-spectrum (SWI...
Reports on patients who lack ownership over their entire body are extremely rare. Here, we present patient SA suffered from complete disownership after a tumour resection in the right temporoparietal cortex. Neuropsychological assessment disclosed selective bilateral problems, despite intact primary visual and somatosensory senses. 's seems to stem suboptimal multimodal integration, as shown by rubber hand illusion beneficial effect during simple exercises aiming at multisensory recalibration.
Abstract Study Objectives Encephalopathy with electrical status epilepticus in sleep (ESES) is characterized by non-rapid eye movement (non-REM)-sleep-induced epileptiform activity and acquired cognitive deficits. The synaptic homeostasis hypothesis describes the process of daytime potentiation balanced downscaling non-REM-sleep considered crucial to retain an efficient cortical network. We aimed study overnight decline slow waves, indirect marker downscaling, patients ESES explore whether...
Epileptische encefalopathie met Elektrische Status Epilepticus in Slaap (ESES) is een epilepsie-syndroom waarbij epileptiforme activiteit vooral, of soms zelfs uitsluitend, tijdens slaap voorkomt. Het komt voor bij kinderen vanaf twee jaar klinische verschijnselen die gekenmerkt worden door achteruitgang cognitief functioneren. Bijna alle (80-90%) hebben ook epileptische aanvallen (in waak vanuit slaap). Hier de verschijnselen, etiologie, diagnostiek en behandeling van dit syndroom besproken.
Abstract Background: Epileptic encephalopathy with electrical status epilepticus in sleep (ESES) is an epilepsy syndrome occurring almost exclusively children, usually at age between 4 and 12 years. It characterized by abundant sleep-induced epileptic activity the electroencephalogram (EEG) acquired cognitive behavioural deficits. The goal of treatment to prevent further decline or even improve functioning. Based on mostly small retrospective studies, corticosteroids clobazam are regarded...
Abstract Background: Epileptic encephalopathy with electrical status epilepticus in sleep (ESES) is an epilepsy syndrome occurring almost exclusively children, usually at age between 4 and 12 years. It characterized by abundant sleep-induced epileptic activity the electroencephalogram (EEG) acquired cognitive behavioural deficits. The goal of treatment to prevent further decline or even improve functioning. Based on mostly small retrospective studies, corticosteroids clobazam are regarded...