A5083944567- Legume Nitrogen Fixing Symbiosis
- Agronomic Practices and Intercropping Systems
- Plant nutrient uptake and metabolism
- Soybean genetics and cultivation
- Genetic and Environmental Crop Studies
- Nematode management and characterization studies
- Agriculture and Biological Studies
- Viral Infectious Diseases and Gene Expression in Insects
- Plant-Microbe Interactions and Immunity
- Plant Gene Expression Analysis
- Single-cell and spatial transcriptomics
- Fungal and yeast genetics research
- Parasitic Infections and Diagnostics
- Acute Myeloid Leukemia Research
- Phagocytosis and Immune Regulation
- Insect Resistance and Genetics
- Extracellular vesicles in disease
All-Russian Research Institute of Agricultural Microbiology
2017-2025
St Petersburg University
2020-2023
Princess Máxima Center
2023
Federal Agency for Scientific Organizations
2016
Efferocytosis, the efficient clearance of apoptotic cells (ACs) by phagocytes, is vital for maintaining tissue homeostasis. Here, we reveal role secreted protein NimB1 in reducing cell recognition and binding early stages efferocytosis. expressed macrophages (also called plasmatocytes) binds to ACs a phosphatidylserine-dependent manner. Structural analysis shows that shares striking similarities with bridging molecule NimB4, possesses two phosphatidylserine-binding motifs, supporting its...
The key event that initiates nodule organogenesis is the perception of bacterial signal molecules, Nod factors, triggering a complex responses in epidermal and cortical cells root. factor signaling pathway interacts with plant hormones, including cytokinins gibberellins. Activation cytokinin through homeodomain-containing transcription factors KNOX essential for formation. main regulators gibberellin signaling, DELLA proteins are also involved regulation However, interaction between pathways...
The present work was designed to study the role of phytohormones, cytokinin and auxin, in symbiosis development between pea Pisum sativum L. Rhizobium leguminosarum bv. viciae. To achieve this aim, temporal expression patterns genes related auxin biosynthesis, perception, response were studied. It found that most these showed specific transcriptional regulations upon nodulation at various stages following inoculation. Once they purified using chromatographic methods, endogenous cytokinins...
Single three-amino acid loop extension (TALE) homeodomain proteins, including the KNOTTED-like (KNOX) and BEL-like (BELL) families in plants, usually work as heterodimeric transcription factor complexes to regulate different developmental processes, often via effects on phytohormonal pathways. Nitrogen-fixing nodule formation legumes is regulated by of factors. Whereas role KNOX factors control symbiosis was studied early, BELL have received less attention. Here, we report identification...
This study focused on the interactions of pea (Pisum sativum L.) plants with phytopathogenic and beneficial fungi. Here, we examined whether lysin-motif (LysM) receptor-like kinase PsLYK9 is directly involved in perception long- short-chain chitooligosaccharides (COs) released after hydrolysis cell walls fungi identified arbuscular mycorrhizal (AM) fungal exudates. The identification analysis mutants impaired lyk9 gene confirmed involvement symbiosis development AM Additionally, regulated...
Traditional sanitation practices remain the main strategy for controlling Bombyx mori infections caused by microsporidia Nosema bombycis. This actualizes development of new approaches to increase silkworm resistance this parasite. Here, we constructed a mouse scFv library against outer loops N. bombycis ATP/ADP carriers and selected nine fragments transporter, highly expressed in early stages parasite intracellular growth. Expression genes Sf9 cells, their infection with different ratios...
The IPD3/CYCLOPS transcription factor was shown to be involved in the regulation of nodule primordia development and subsequent stages differentiation. In contrast early stages, related differentiation remain less studied. Recently, we have that accumulation cytokinin at later may significantly impact development. This conclusion based on a comparative analysis localization between pea wild type ipd3/cyclops mutants. However, role these nodulation is still far from understood. To determine...
The development of legume–rhizobial symbiosis results in the formation nitrogen-fixing root nodules. In response to rhizobial molecules, Nod factors, signal transduction is mediated by interaction activated receptors with downstream signaling proteins. Previously, some new regulators pathway, such as phospholipases D, which regulate level phosphatidic acid (PA), well mitogen-activated protein kinases (MAPKs), have been identified legumes. Since PA an important messenger, we tested hypothesis...
The development of legume-rhizobium symbiosis is based on signal exchange between partners, which leads to the formation nitrogen-fixing root nodules. Under influence rhizobial molecules, Nod factors, transduction cascade activated, where LysM-type receptor kinases and a complex intracellular regulators, significant part are still unknown, can play an important role.
 Using transcriptomic proteomic analysis, we searched for new regulators pathway in pea Pisum sativum L., activated under...
BACKGROUND: The method of protein-protein interaction analysis using the yeast two-hybrid system in Saccharomyces cerevisiae cells is used to search for protein coregulators. This also mass screening libraries cloned fragments complementary DNA (cDNA) that are translated cell. key factor success such level efficiency cell transformation, since resolution based on this. AIM: aim this study optimal parameters chemical transformation increase cDNA library screening. MATERIALS AND METHODS:...
This review refers to analysis of the modern data about role auxins in regulation nitrogen-fixing nodule development legume plants.The interaction these hormones with cytokinins and components signaling cascade activated by Nod factors during organogenesis plants different types nodules are discussed.Emphasis is being given participation control initiation early stages development.In works transgenic containing fusions between promoters regulated reporter genes, showed accumulation places...
Mutualistic symbioses formed by garden pea have been studied with use of ‘omic’ technologies in order to gain a new understanding molecular mechanisms beneficial effect that microsymbionts on seed yield and quality. 
 Keywords: pea, transcriptomics, nitrogen fixation, arbuscular mycorrhiza, PGPB
The development of nitrogen-fixing nodule, which is formed during legume-rhizobial symbiosis, requires the involvement cell cycle regulators, phytohormones and homeodomain-containing transcription factors as well other organogenesis processes. Along with homedomain-containing from KNOX family, participation in control nodule has been studied recently, role BELL family this process remains under-explored. At same time, transcriptomic data for legumes shows an increase expression levels genes...
Background: Leukemias constitute the most frequent pediatric cancers. Acute myeloid leukemias (AMLs) are often characterised by aberrant fusion proteins that initiate and drive disease. Fusion like RUNX1::RUNX1T1, CBFβ::MYH11 or KMT2A corrupt transcriptional networks leading to impaired cell differentiation enhanced malignant proliferation. While intrinsic effects of genes on leukemic subject intensive research, much less is known about how affect communication within its microenvironment....
Министерство науки и высшего образования РФ Российская академия наук Общество физиологов растений России Правительство Республики Татарстан Федеральный исследовательский центр «Казанский научный Российской академии наук» Казанский институт биохимии биофизики ФИЦ КазНЦ РАН Институт физиологии им.К.А
Interconnection between key transcription factors of symbiosis regulation and the homeodomain-containing KNOXs BELLs in development nodules pea was investigated.