A5087660153- Heavy Metal Exposure and Toxicity
- Heavy metals in environment
- Vitamin D Research Studies
- Vibrio bacteria research studies
- Genetics, Aging, and Longevity in Model Organisms
- Per- and polyfluoroalkyl substances research
- Gut microbiota and health
- Selenium in Biological Systems
- Yersinia bacterium, plague, ectoparasites research
- Trace Elements in Health
- Environmental Toxicology and Ecotoxicology
- Bacterial Genetics and Biotechnology
- Effects and risks of endocrine disrupting chemicals
Örebro University
2022-2023
Umeå University
2012
Exposure to toxic metals alters host response and that leads disease development. Studies have revealed the effects of on microbial physiology, however, role metal resistant bacteria is unclear. The hypothesis xenobiotic interactions between gut microbes arsenic influence physiology toxicity was assessed in a Caenorhabditis elegans model. arsenic-resistant Lysinibacillus sphaericus B1CDA fed C. determine responses comparison Escherichia coli OP50 food. L. diet extended lifespan compared E....
Metal contamination of aquatic environments remains a major concern and has received significant attention in recent years. The present study aimed to evaluate the effects metal mixtures varying concentrations over time lake receiving runoff water from decommissioned mine. By subjecting several organisms this water, we identify most susceptible species, thus enabling comprehensive evaluation risk posed by different toxins biotic environment. We have evaluated mixed exposure on survival...
Abstract Background The CpxA sensor kinase-CpxR response regulator two-component regulatory system is a sentinel of bacterial envelope integrity. Integrating diverse signals, it can alter the expression wide array components that serve to shield from damage and promote survival. In pathogens such as Yersinia pseudotuberculosis , this also extends pathogenesis. CpxR thought dimerize upon phosphorylation by kinase CpxA. This enables binding specific DNA sequences where acts on gene...
Per- and Poly-fluoroalkyl substances (PFAS) are major persistent environmental contaminants. Epidemiological studies have linked PFAS exposures to altered immunity increased occurrence of infections in children. However, the mechanisms leading immune susceptibility bacterial remains unclear. To elucidate mechanism, transcriptional alteration Caenorhabditis elegans model caused by a contaminated water two reconstituted solutions were evaluated using RNA-sequencing. affected expression several...
Metal contamination of aquatic environments remains a major concern and has received significant attention in recent years. The present study aimed to evaluate the effects metal mixtures varying concentrations over time lake receiving runoff water from decommissioned mine. By subjecting several organisms this water, we identify most susceptible species, thus enabling comprehensive evaluation risk posed by different toxins biotic environment.We have evaluated mixed exposure on survival stress...