A5027026851- Cerebral Palsy and Movement Disorders
- Spinal Cord Injury Research
- Stroke Rehabilitation and Recovery
- Balance, Gait, and Falls Prevention
- Muscle activation and electromyography studies
- Nerve Injury and Rehabilitation
- Transcranial Magnetic Stimulation Studies
- Traumatic Brain Injury Research
- Infant Development and Preterm Care
- Musculoskeletal pain and rehabilitation
- Spinal Dysraphism and Malformations
- Botulinum Toxin and Related Neurological Disorders
- Parkinson's Disease Mechanisms and Treatments
- Neuroscience of respiration and sleep
- Acute Ischemic Stroke Management
- Occupational Therapy Practice and Research
- Vestibular and auditory disorders
- Respiratory Support and Mechanisms
- Botany, Ecology, and Taxonomy Studies
- Motor Control and Adaptation
- Neurology and Historical Studies
- Mental Health and Patient Involvement
- Biological and pharmacological studies of plants
- Mechanics and Biomechanics Studies
- Assistive Technology in Communication and Mobility
University of Louisville
2016-2025
Neurological Surgery
2015-2025
Kosair Charities
2019-2024
Kentuckiana Pulmonary Associates
2017
Rehabilitation Institute of Michigan
2017
University of Florida
2006-2016
Malcom Randall VA Medical Center
2006-2016
University of Southern California
2012-2016
AdventHealth Orlando
2016
MetroHealth
2016
Locomotor training, including the use of body-weight support in treadmill stepping, is a physical therapy intervention used to improve recovery ability walk after stroke. The effectiveness and appropriate timing this have not been established.We stratified 408 participants who had stroke 2 months earlier according extent walking impairment--moderate (able 0.4 <0.8 m per second) or severe <0.4 second)--and randomly assigned them one three training groups. One group received on with occurred...
Many individuals with spinal cord injury (SCI) do not regain their ability to walk, even though it is a primary goal of rehabilitation. Mammals thoracic transection can relearn step hind limbs on treadmill when trained sensory input associated stepping. If humans have similar neural mechanisms for locomotion, then providing comparable training may promote locomotor recovery after SCI. We used designed provide information locomotion improve stepping and walking in adults Four SCIs, mean...
The interaural time difference (ITD) is a cue for localizing sound source along the horizontal plane and first determined in nucleus laminaris (NL) birds. Neurons NL are tonotopically organized, such that ITDs processed separately at each characteristic frequency (CF). Here, we investigated excitability coincidence detection of neurons tonotopic axis NL, using chick brainstem slice preparation. Systematic changes with CF were observed morphological electrophysiological properties neurons....
Background and Purpose —After stroke, many individuals have chronic unilateral motor dysfunction in the upper extremity that severely limits their functional movement control. The purpose of this study was to determine effect electromyography-triggered neuromuscular electrical stimulation on wrist finger extension muscles who had a stroke ≥1 year earlier. Methods —Eleven volunteered participate were randomly assigned either experimental group (7 subjects) or control (4 subjects). After...
Background. For clinical trials in stroke rehabilitation, self-selected walking speed has been used to stratify persons predict functional status and define meaningfulness of changes. However, this stratification was validated primarily using self-report questionnaires. Objective. This study aims validate the speed-based classification system with quantitative measures performance. Methods. A total 59 individuals who had hemiparesis for more than 6 months after participated study....
Locomotor training using body weight support and a treadmill as therapeutic modality for rehabilitation of walking post-stroke is being rapidly adopted into clinical practice. There an urgent need well-designed trial to determine the effectiveness this intervention. The objective Experience Applied Post-Stroke (LEAPS) if there difference in proportion participants who recover ability at one year when randomized specialized locomotor program (LTP), conducted 2- or 6-months post-stroke, those...
Background. The Spinal Cord Injury Locomotor Trial (SCILT) compared 12 weeks of step training with body weight support on a treadmill (BWSTT) that included overground practice to defined but more conventional mobility intervention (CONT) in patients incomplete traumatic SCI within 8 onset. No previous studies have reported walking-related outcomes during rehabilitation. Methods. This single-blinded, randomized trial entered 107 American Association (ASIA) C and D 38 ASIA B lesions between C5...
The use of locomotor training with a body-weight-support system and treadmill (BWST) manual assistance has increased in rehabilitation. purpose this case report is to describe the process for retraining walking person an incomplete spinal cord injury (SCI) using BWST transferring skills from overground assessment community ambulation.Following discharge rehabilitation, man SCI at C5-6 American Spinal Injury Association (ASIA) Impairment Scale classification D participated 45 sessions...
Background and Purpose— Constraint-induced movement therapy (CIMT) is a rehabilitative strategy used primarily with the post-stroke population to increase functional use of neurologically weaker upper extremity through massed practice while restraining lesser involved extremity. Whereas research evidence supports CIMT, limited exists regarding characteristics individuals who benefit most from this intervention. The goal study was investigate potential 5 measures predict CIMT outcomes....
Background. Locomotor training using partial body weight-supported treadmill (BWST) walking has been widely investigated for people after stroke, yet there remains a lack of evidence concerning the optimal duration and effect locomotor impairment severity. Previous protocols have not emphasized transfer skills from BWST environment to overground. Objectives. To assess feasibility program combining with task-specific overground obtain pilot data on effects severity recovery locomotion....
Rationale: Intermittent stimulation of the respiratory system with hypoxia causes persistent increases in motor output (i.e., long-term facilitation) animals spinal cord injury. This paradigm, therefore, has been touted as a potential rehabilitation strategy.Objectives: To determine whether acute (daily) exposure to intermittent can also evoke facilitation ventilation after chronic injury humans, and repeated daily enhances magnitude this response.Methods: Eight individuals incomplete (>1...
The authors describe the rationale and methodology for first prospective, multicenter, randomized clinical trial (RCT) of a task-oriented walking intervention subjects during early rehabilitation an acute traumatic spinal cord injury (SCI). experimental strategy, body weight-supported treadmill training (BWSTT), allows physical therapists to systematically train patients walk on at increasing speeds typical community ambulation with weight bearing. provide verbal tactile cues facilitate...
Gait in Parkinson's disease is characterised by slowed velocity; shuffling, small steps; and absent arm swing. Drug therapy intervention beneficial improving mobility, though with prolonged use its effects may diminish. The purpose of this study was to examine whether Parkinsonian patients could improve their gait patterns response five instructional sets: natural walking; walking while deliberately swinging the arms; large fast counting aloud. Eight subjects idiopathic eight age matched...
Background. Rehabilitation services after hip arthroplasty (HA) usually occur in the first 6 months following surgery. Reports literature suggest that 9 to several years HA surgery, patients are generally satisfied with pain relief. However, many express dissatisfaction their ability perform domestic and social activities. Reduced walking long-term lower extremity (LE) muscle weakness may contribute decreased mobility. The purpose of this study was compare within-group LE strength, gait,...
Objective. To demonstrate criterion (concurrent and predictive) construct validity of the Walking Index for Spinal Cord Injury (WISCI) scale other walking measures in Locomotor Trial (SCILT). Design. Prospective multicenter clinical trial a intervention patients with acute traumatic spinal cord injury (SCI). Participants/Methods. Body weight−supported treadmill training was compared to overground mobility 146 incomplete SCI (C4 L3) enrolled within 8 weeks onset treated 12 weeks. Primary...
Background and Purpose Locomotor training (LT) enhances walking in adult experimental animals humans with mild-to-moderate spinal cord injuries (SCIs). The animal literature suggests that the effects of LT may be greater on an immature nervous system than a mature system. purpose this study was to evaluate child chronic, incomplete SCI. Subject subject nonambulatory 4½-year-old boy American Spinal Injury Association Impairment Scale (AIS) C Lower Extremity Motor Score (LEMS) 4/50 who deemed...
Better understanding of fall risk poststroke is required for developing screening and prevention programs. This study characterizes falls in the Locomotor Experience Applied Post-Stroke (LEAPS) randomized clinical trial, describes impact 2 walking recovery interventions on falls, examines value assessments predicting falls.Community-dwelling ambulatory stroke survivors enrolled LEAPS were assessed months poststroke. Falls monitored until 12 participants characterized as multiple or injurious...