A5020213636- Research on Leishmaniasis Studies
- Vector-borne infectious diseases
- Parasites and Host Interactions
- Insect and Pesticide Research
- Trypanosoma species research and implications
- Toxin Mechanisms and Immunotoxins
Universidade Federal de Minas Gerais
2019-2023
Endemic in Brazil, visceral leishmaniasis (VL) is a zoonotic infection that among the most important parasitic diseases transmitted by vectors. Dogs are main reservoirs of canine (CanL) and their identification used some countries as part disease prevention control measures human population. In this context, serological tests necessary, composed antigens capable correctly identifying infected dogs, minimizing number false-negative cases. This study aimed to identify more immunoreactive...
Visceral leishmaniasis (VL) is a fatal disease caused by the protozoa Leishmania infantum for which dogs are main reservoirs. A vaccine against canine visceral (CVL) could be an important tool in control of human and CVL reducing infection pressure L. infantum. Despite available on market, Brazilian Ministry Health did not implement use it their programs. In this sense, there urgent need to develop more efficient vaccines. study, association between two polymeric nanoformulations, (poly (D,...
Leishmaniasis is a widespread vector-borne disease in Brazil, with Leishmania (Leishmania) infantum as the primary etiological agent of visceral leishmaniasis (VL). Dogs are considered main reservoir this parasite, whose treatment Brazil restricted to use veterinary medicines, which do not promote parasitological cure. Therefore, efficient vaccine development best approach Canine Visceral (CVL) control. With mind, study used hamsters (Mesocricetus auratus) an experimental model...
Visceral leishmaniasis is an important global health problem with estimated of 50,000 to 90,000 new cases per year. VL the most serious form as it can be fatal in 95% if remains untreated. a particularly acute Brazil which contributed 97% all reported 2020 Americas. In this country, affects mainly poorest people both urban and rural areas continues have high mortality rate around 8.15%. Here, we performed temporal parasite population study using whole genome sequence data from set 34 canine...