A5048201470- Synthesis and Characterization of Heterocyclic Compounds
- Synthesis and biological activity
- Sugarcane Cultivation and Processing
- Diverse Scientific Research Studies
- Synthesis and Reactions of Organic Compounds
- Organic Chemistry Cycloaddition Reactions
- Chemical Synthesis and Reactions
- Essential Oils and Antimicrobial Activity
- Nanoparticles: synthesis and applications
- Pharmacological Effects of Natural Compounds
- Chemical Synthesis and Analysis
- Retinoids in leukemia and cellular processes
- Computational Drug Discovery Methods
- Organoselenium and organotellurium chemistry
- Click Chemistry and Applications
- Metal complexes synthesis and properties
- Synthesis and Biological Evaluation
- Natural Antidiabetic Agents Studies
- Synthesis and Biological Activity
- Chromatography in Natural Products
- Acne and Rosacea Treatments and Effects
- Nanocomposite Films for Food Packaging
- Dendrimers and Hyperbranched Polymers
- Hip and Femur Fractures
- Natural Fiber Reinforced Composites
Guangxi Academy of Agricultural Science
2023-2024
Indian Institute of Technology Kanpur
2017-2023
Delhi Technological University
2023
Dr. Hari Singh Gour University
2021
Chirayu Medical College & Hospital
2019
National Institute of Pharmaceutical Education and Research
2018
Kurukshetra University
2017
Maharshi Dayanand University
2011
University of Lucknow
1987-1988
Gauhati University
1977-1979
The emergence of resistance against antimicrobial agents has led to the development more efficient and new techniques for treatment various microbial infections. aim present study is determine antibacterial antifungal activity bare chitosan coated Fe3O4 nanoparticles (NPs) five organisms, Escherichia coli (E. coli), Bacillus subtilis (B. subtilis), Candida albicans (C. albicans), Aspergillus niger (A. niger) Fusarium solani (F. solani).Fe3O4 NPs were synthesised by coprecipitation surface...
A new chromogen that absorbs maximally at 329 nm was frequently found in the liver oils of freshwater fish Bagarius bagarius and Wallago attu. It shown to be a diester 3-hydroxyretinol. 3-Hydroxyretinol metabolite lutein during biosynthesis 3-dehydroretinol fish. method for chemical synthesis 3-hydroxyretinol from methyl 3-dehydroretinoate is described. The possible pathway conversion into vivo discussed.
Introduction: Rapid global emergence of antimicrobial resistance led to the failure many antibiotics available in market. Among multi drug resistant Gram +ve bacteria, methicillin and vancomycin resistant, Staphylococcus aureus strains are leading causes nosocomial infections involving skin, soft tissues urinary tract. Therefore, search for new targets that unique gram positive bacteria is a promising strategy design novel antibacterial agents. Recently, lipoteichoic acid, bacterial cell...
The synthesis of 10-membered and 12-membered tellurium containing tetraazamacrocyclic complexes divalent nickel palladium by template condensation diaryltellurium dichlorides, (aryl = p-hydroxyphenyl, 3-methyl-4-hydroxyphenyl, p-methoxyphenyl) with 1,2-diaminoethane 1,3-diaminopropane in the presence metal dichloride is reported. resulting have been subjected to elemental analyses, magnetic measurements, electronic absorption, infra-red, proton resonance spectral studies. formation proposed...
Background: In the present study, 4, 5-disubstituted triazol-3-thione derivatives were synthesized and evaluated for anticonvulsant activity along with neurotoxicity determination. Materials Methods: The compounds characterized using FTIR, 1H-NMR MS. was assessed by Maximal Electroshock (MES) test subcutaneous Pentylenetetrazole (scPTZ) tests rotarod test. Docking also performed to study interactions of LYS329 residue gamma amino butyric acid aminotransferase (GABA-AT) Autodock 4.2 software....
Withania somnifera L (or Ashwagandha or Indian ginseng) is a sub-tropical medicinal plant of Solanaceae family that used by folk healers for multipurpose ailments in alternative system treatment. It serves as bioactive ingredient more than 100 ayurvedic formulations Ayurveda, Siddha, and Unani medication. The ethnopharmacological application includes adaptogenic, anti-convulsion, anti-microbial anti-sedative, anti-stress, arthritis, geriatric debilities, mental disorders, neurological...
Epilepsy is the most general, extensive, and severe neurological disorder, affecting more than 50 million individuals globally. Initially, conventional medicines simple salts like potassium bromide were employed as antiepileptic medication candidates. Nowadays, many anticonvulsant drugs have been discovered first-generation second-generation newer are still in development phases. The pharmacophore-based drug design process includes pharmacophore modeling validation, virtual screening, hits...
In the present study, we synthesized fifteen 4, 5-disubstituted 1, 2, 4-triazol- 3-thione derivatives and evaluated for anticonvulsant activity with neurotoxicity determination.The compounds were characterized using FTIR, 1H-NMR MS. The molecular docking study was also performed to interactions of LYS329 residue gamma amino butyric acid aminotransferase (GABA-AT) Autodock 4.2 software. assessed by maximal electroshock (MES) test subcutaneous pentylenetetrazol (scPTZ) tests. rotarod ataxia...
A series of Menthone semicarbazone and thiosemicarbazone derivatives (3a-h) were synthesized characterized by their spectral data screened for anticonvulsant analgesic activity. Compounds investigated showed significant activity
Oriental Journal of Chemistry is a peer reviewed quarterly research journal pure and applied chemistry. It publishes standard papers in almost all thrust areas current chemistry academic commercial importance. provides platform for rapid publication quality papers, reviews letters. abstracted indexed reputed National International agencies.
The structure of naturally occurring anhydrovitamin A2 was elucidated as 3-hydroxyanhydroretinol from study its u.v.–visible, i.r., n.m.r. and mass spectra. has been confirmed by a chemical synthesis. Saccobranchus fossils, freshwater fish, can convert 3-hydroxyretinol into 3-hydroxyanhydroretinol, which in turn is converted into-3-dehydroretinol. Chemical conversion 3-dehydroretinol also carried out.
First total synthesis of carpatamide-A 7a, cytotoxic arylamine derivative isolated from marine derived Streptomyces sp., was achieved in twelve steps with overall yield 24% seven longest linear steps. In the penultimate step, dienoic acid 13 and an amino-phenylpropionic methyl ester core 21 were coupled to synthesize methylated derivativative 22 followed by demethylation intermediate BBr3 accomplish 7a. Both precursors synthesized readily available starting materials i.e. isovaleraldehyde 8...