- Cardiac pacing and defibrillation studies
- Heart Failure Treatment and Management
- Cardiac Arrhythmias and Treatments
- Cardiac Structural Anomalies and Repair
- Cardiac electrophysiology and arrhythmias
- Palliative Care and End-of-Life Issues
- Heart Rate Variability and Autonomic Control
- Vagus Nerve Stimulation Research
- Cardiovascular Effects of Exercise
- Salmonella and Campylobacter epidemiology
- COVID-19 and Mental Health
- Obesity, Physical Activity, Diet
- EEG and Brain-Computer Interfaces
- Pulmonary Hypertension Research and Treatments
- Muscle activation and electromyography studies
- Family and Patient Care in Intensive Care Units
- Transplantation: Methods and Outcomes
- Consumer Attitudes and Food Labeling
- Cardiomyopathy and Myosin Studies
- Listeria monocytogenes in Food Safety
- Electrolyte and hormonal disorders
- Patient-Provider Communication in Healthcare
- Mechanical Circulatory Support Devices
- Mental Health Treatment and Access
- Cardiovascular Function and Risk Factors
Baylor College of Medicine
2023
Harvard University
2012-2021
Massachusetts General Hospital
2009-2021
Newton Wellesley Hospital
2016-2021
Brigham and Women's Hospital
2016-2021
Spaulding Rehabilitation Hospital
2019-2020
Sheba Medical Center
2019
VA Boston Healthcare System
2016-2018
Boston University
2013-2016
Tufts University
2016
Concentrations of soluble (s)ST2 predict prognosis in heart failure. We recently found changing doses β-blocker (BB) may affect sST2 concentrations. It remains unclear whether concentrations identify benefit BB therapy, however.A total 151 subjects with failure attributable to left ventricular systolic dysfunction were examined this post hoc analysis; >96% taking at enrollment. Medication regimen and values obtained during 10 months. Cardiovascular events as a function baseline status (low...
Background: Conversations about goals of care and cardiopulmonary resuscitation (CPR)/intubation for patients with advanced heart failure can be difficult. This study examined the impact a video decision support tool patient checklist on advance planning failure. Methods: was multisite, randomized, controlled trial video-assisted intervention versus verbal description in 246 ≥64 years age an estimated likelihood death >50% within 2 years. Intervention participants received...
Intensive remote monitoring programs for congestive heart failure have been successful in reducing costly readmissions, but may not be appropriate all patients. There is an opportunity to leverage the increasing accessibility of mobile technologies and consumer-facing digital devices empower patients their own health outside hospital setting. The iGetBetter system, a secure Web- telephone-based program, which leverages technology portable devices, offers creative solution at lower cost.The...
Several studies have reported a poor outcome with cardiac resynchronization therapy (CRT) in non-left bundle branch block (LBBB) patients. Although the left ventricular (LV) lead location is an important determinant of clinical outcome, there scant information regarding its role non-LBBB This study sought to examine impact electrical and anatomical LV relation baseline QRS morphology on CRT outcome.A delay (LVLED) was measured intra-procedurally as interval between onset surface...
Background Low‐level tragus stimulation (LLTS) has been shown to significantly reduce atrial fibrillation (AF) burden in patients with paroxysmal AF. P‐wave alternans (PWA) is believed be generated by the same substrate responsible for Hence, PWA may serve as a marker guiding LLTS therapy. We investigated utility of therapy Methods and Results Twenty‐eight AF were randomized either active or sham (earlobe stimulation). was delivered through transcutaneous electrical nerve device (pulse width...
Many proven heart failure (HF) therapies decrease N‐terminal pro B‐type natriuretic peptide (NT‐proBNP) values over time, yet some patients have an NT‐proBNP >1000 pg/ mL following treatment, which is associated with poor outcomes. A total of 151 left ventricular systolic dysfunction were treated aggressive HF therapy in the ProBNP Outpatient Tailored Chronic Heart Failure (PROTECT) study. Clinical characteristics and measured at each visit during 10 months. In this post hoc analysis,...
The coronavirus pandemic enforced social restrictions with abrupt impacts on mental health and changes to behaviors. From a randomized clinical trial, we assessed the impact of culinary education home cooking practices, coping strategies resiliency during first wave COVID-19 (March/April 2020). Participants (n = 28) were aged 25-70 years BMI 27.5-35 kg/m2. intervention consisted 12 weekly 30-min one-on-one telemedicine coaching sessions. Coping through Brief Problems Experienced Inventory,...
Abstract Background: One‐third of patients who receive cardiac resynchronization therapy (CRT) are classified as nonresponders. Characteristics responders to CRT have been studied in multiple clinical trials. Hypothesis: Independent predictors response may be identified by studying a series routine practice. Method: One hundred twenty‐five were examined retrospectively from multidisciplinary clinic program. Echocardiographic was defined decrease left ventricular (LV) end‐systolic volume ≥15%...
This study examined the prognostic significance of pre- and post-capillary components pulmonary hypertension (PH) in patients receiving cardiac resynchronization therapy (CRT).PH is common with left ventricular systolic dysfunction (LVSD) CRT. The impact PH subtype on clinical outcome CRT unknown.The population consisted 101 (average age 66 ± 13 years, ejection fraction 0.23 0.07, New York Heart Association functional class 3.2 0.4) who underwent right heart catheterization 6 months before...
Recent findings reveal that suboptimal diet is responsible for more deaths than any other risk factor nationally and globally. It estimated with improving eating behaviors, 1 in 5 can be prevented, underscoring the urgent need effective dietary interventions.
Paid family and medical leave (PFML) helps parents balance the competing obligations of work, personal illness, family. PFML is needed when adding a new member or individual becomes acutely chronically ill. The United States lacks universally available PFML, despite benefits for child health well-being. Universally key component improving children families critically in States.
The increasing prevalence, high symptom burden, and medical advances that often prolong the advanced phase of heart failure mandate an organized thoughtful approach to decision making. However, many clinicians have difficulty discussing prognosis goals care with patients. Barriers include disease- therapy-specific prognostication challenges in a lack evidence-based primary palliative education initiatives.In response, we developed this 45-minute training module, which consists case-based...
One of the principles culinary medicine is to help patients learn how make nutritious eating simple and easy. In this column, you will tools for preparing storing food; a key component successful home cooking. While article intended clinicians about food preparation, it also designed be used as an educational tool patients.
Aims: Microvolt T-wave alternans (TWA), an oscillation in morphology of the electrocardiogram (ECG), has been associated with increased susceptibility to ventricular tachy-arrhythmias, while vagus nerve stimulation shown promising anti-arrhythmic effects vivo and ex animal studies. We aimed examine effect non-invasive, acute low-level tragus (LLTS) on TWA patients ischemic cardiomyopathy heart failure. Methods: 26 (left ejection fraction <35%) chronic stable failure, previously...
Cardiac valve surgery (CVS) has been implicated as a potential barrier to optimal response after cardiac resynchronization therapy (CRT) though prospective data regarding outcome remains limited. We sought determine CRT in patients with prior history of CVS.We performed retrospective analysis prospectively acquired cohort CVS. Echocardiographic was evaluated at baseline and 6 months. The coprimary endpoints were time first heart failure (HF) hospitalization composite all-cause mortality,...