- Cardiac electrophysiology and arrhythmias
- Cardiac pacing and defibrillation studies
- Cardiac Arrhythmias and Treatments
- Atrial Fibrillation Management and Outcomes
- ECG Monitoring and Analysis
- Cardiac Imaging and Diagnostics
- Cardiovascular Function and Risk Factors
- Cardiomyopathy and Myosin Studies
- Cardiovascular Effects of Exercise
- Chronic Lymphocytic Leukemia Research
- HER2/EGFR in Cancer Research
- Genetic Associations and Epidemiology
- BRCA gene mutations in cancer
- Venous Thromboembolism Diagnosis and Management
- Heart Failure Treatment and Management
- Cancer-related gene regulation
- Neuroendocrine Tumor Research Advances
- Organ Transplantation Techniques and Outcomes
- Heart Rate Variability and Autonomic Control
- Renal Transplantation Outcomes and Treatments
- Cardiovascular Syncope and Autonomic Disorders
- Acute Myocardial Infarction Research
- Transplantation: Methods and Outcomes
Cook County Health and Hospitals System
2020-2023
Rush University Medical Center
2018-2022
John H. Stroger, Jr. Hospital of Cook County
2020-2022
Thomas Jefferson University Hospital
2014
University at Buffalo, State University of New York
2012-2013
University of Rochester Medical Center
2006-2013
University of Rochester
2009-2013
VA Western New York Healthcare System
2013
Gentofte Hospital
2013
QRS fragmentation (fQRS) has been reported as a useful ECG parameter in predicting mortality high-risk postinfarction patients. Its prognostic value for sudden cardiac death (SCD) and ventricular arrhythmias ischemic cardiomyopathy (ICM) remains unknown.MADIT II enrollment 12-lead ECGs were analyzed fQRS defined RSR' patterns (≥1 R' or notching of S R wave) patients with normal duration >2 notches on the wave abnormal duration, present 2 contiguous leads. Exclusion criteria included paced...
Background: Obesity, as defined by body mass index ≥30 kg/m 2 , has been shown to be a risk factor for cardiovascular disease. However, data on the relationship between (BMI) and of ventricular arrhythmias sudden cardiac death are limited. The aim this study was evaluate tachyarrhythmias BMI in patients after myocardial infarction with severe left dysfunction. Methods : appropriate defibrillator therapy tachycardia or fibrillation (VT/VF) status analyzed 476 nondiabetic dysfunction who...
Background Conventional right ventricular pacing (RVP) has been associated with an increased incidence of atrial fibrillation (AF). We sought to compare the occurrence new-onset AF and assessed disease progression during long-term follow-up between His bundle (HBP) RVP. Methods Results included patients undergoing initial dual-chamber pacemaker implants at Rush University Medical Center January 1, 2016, June 30, 2019. A total 360 were evaluated, 225 (HBP, n=105; RVP, n=120) in study. Among...
Abstract Background Persistent atrial fibrillation (AF) is associated with high recurrence rates of AF and atypical flutters or tachycardia (AFT) postablation. Laser balloon (LB) ablation the pulmonary vein (PV) ostia has similar efficacy as radiofrequency wide area circumferential (RF‐WACA); however, an approach LB (LB‐WACA) may further improve success rates. Objective To evaluate freedom from tachyarrhythmia (AFT/AF) postablation using RF‐WACA versus LB‐WACA in persistent patients. Methods...
Twiddler's syndrome is a poorly understood clinical phenomenon when patients either consciously or subconsciously rotate their cardiac device resulting in lead dislodgement. We aimed to determine the true prevalence and risk factors associated with real-world population.A retrospective chart review was performed on all who underwent implantation from January 1st 2017 until Jan 2022. specifically searched for terms "Twiddler" "Twiddler's" imbedded within text of medical chart. Demographic...
Background : Prophylactic therapy with the implantable cardioverter defibrillator (ICD) reduces mortality among patients left ventricular dysfunction; however, life‐prolonging device has been shown to be associated an increased risk for subsequent heart failure (HF) events. There are limited data on effect of primary types HF medications, angiotensin converting enzyme inhibitors (ACE‐I), and beta‐blockers progression in ICD‐treated patients. Methods Multivariate Cox proportional hazards...
Left atrial appendage occlusion (LAAO) devices are increasingly being used in patients with elevated stroke risk who also have high bleeding risk, but unable to take long-term anticoagulation.1 Safety of fibrillation (AF) ablation following Watchman (Boston Scientific, Natick, MA) device implantation has been reported.2 However, there is limited data on the feasibility and safety pulmonary vein isolation (PVI) after other LAAO devices. We present case a patient history PVI using cryotherapy...
Key Teaching Points•Because of tissue-specific drug accumulation properties, recognizing the association between flecainide and drug-induced acute lung injury is important. Early withdrawal offending agent critical to clinical recovery.•Flecainide-associated remains a diagnosis exclusion. Infectious processes cardiogenic pulmonary edema must be ruled out. A radiographic pattern bilateral or unilateral opacities with ground-glass has been described in previous cases pneumonitis as well our...
Background : Previously identified atherosclerotic genetic factors have been studied mostly in case‐control studies and nonuniform ethnic populations, whereas data on the cumulative contribution of to an earlier onset a first myocardial infarction (MI) are limited. We hypothesized that several single nucleotide polymorphisms (SNPs) may exert additive effect occurrence coronary atherothrombotic disease after adjustment for clinical factors. Methods Eighteen high‐risk SNPs were selected based...
Abstract Background Ablation Index (AI) is a novel multiparametric radiofrequency (RF) ablation lesion quality metric, which incorporates contact force, time, and power in weighted formula. AI guided strategies have been shown to be clinically effective for catheter of atrial arrhythmias. The utility guide ventricular tachycardia (VT) patients with structural heart disease not known. Objectives To assess RF procedural characteristics, safety, long-term clinical outcomes undergoing VT using...