A5053287680- Psoriasis: Treatment and Pathogenesis
- Tryptophan and brain disorders
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Dermatology and Skin Diseases
- Reproductive Health and Contraception
- Spondyloarthritis Studies and Treatments
- Body Image and Dysmorphia Studies
- Pregnancy and Medication Impact
- Therapeutic Uses of Natural Elements
- Circadian rhythm and melatonin
- Healthcare professionals’ stress and burnout
- COVID-19 and Mental Health
- Mental Health Treatment and Access
- Health, psychology, and well-being
- Resilience and Mental Health
- Multiple Sclerosis Research Studies
- Allergic Rhinitis and Sensitization
University of Manchester
2020-2025
Greater Manchester Mental Health NHS Foundation Trust
2023-2025
Manchester Academic Health Science Centre
2020-2025
Salford Royal NHS Foundation Trust
2020-2023
NIHR Manchester Biomedical Research Centre
2020-2023
National Institute for Health Research
2022
Salford Royal Hospital
2022
Psoriasis is a chronic systemic inflammatory skin disease, coexisting with depression in up to 25% of patients. Little known about the drivers comorbidity, including shared neurobiology and brain imaging patterns An immune-mediated crosstalk between has been hypothesized psoriasis. With aim investigating structure connectivity psoriasis relation we conducted study largest patient sample date (to our knowledge) first investigate role inflammation measures. Effects psoriatic arthritis (PsA),...
The current COVID-19 pandemic highlights the inextricable link between mental health and chronic skin disease. Furthermore, it is crucial that patients are aware of potential impact pandemic, have clear guidance about how to maintain their wellbeing seek help in case distress. Chronic disease linked psychological distress psychiatric comorbidities, which significantly increase disability these patients. Atopic dermatitis urticaria strongly associated with anxiety depressive symptoms. In...
Abstract Background Psoriasis is associated with poor mental health and reduced quality of life. Although the high risk for depression in patients psoriasis well-established, their suicidality uncertain. Previous studies provide contrasting results have not included clinically-confirmed severe disease. Objectives Our aim was to determine suicide among moderate compared general population, investigate if psychiatric comorbidity or history increases future psoriasis. We further estimated...
Abstract is missing (Short communication)
Despite some evidence that psoriatic arthritis (PsA) may increase psychological burden in psoriasis, the mental health of this subpopulation is under-investigated.To investigate whether PsA associated with higher depression and anxiety moderate-to-severe psoriasis; explore pain mediates these associations; estimate prevalence undiagnosed untreated depression.Baseline data from British Association Dermatologists Biologic Immunomodulators Register (BADBIR) participants completing Hospital...
Psoriasis is regarded as a systemic inflammatory disease; however, the significance of burden for psychiatric comorbidity not clear (Griffiths et al., 2017). A bidirectional association between psoriasis and depression observed, negatively affecting patients’ disability, course, psoriatic arthritis risk (Lewinson Mounting evidence low-grade inflammation in physically healthy individuals with led to hypothesis that immunological processes may drive psoriasis-depression
Abstract Background Illness perceptions in psoriasis have an impact on adherence and disability. Changes dermatological healthcare provision during the Covid‐19 pandemic distress may affected illness patients. Objectives To test whether about changed first year of compared to pre‐pandemic a tertiary population with effects differed depending depressive burden, given this population's high depression prevalence. Methods In cross‐sectional survey n = 188 patients dermatologist‐confirmed...
Abstract Psoriasis is associated with poor mental health, high prevalence of depression and reduced quality life. However, suicide risk in this group unclear. Previous meta-analyses have provided conflicting results regarding suicidality outcomes, including suicidal thoughts attempts suicide. Existing literature has not investigated patients clinically confirmed moderate-to-severe disease. Our aims were to investigate (i) the among psoriasis compared general population (ii) whether...
Abstract Limited evidence suggests an increased lifetime prevalence of illicit drug use in psoriasis. To our knowledge, there are no data for psoriatic arthritis (PsA) this regard. Given the pronounced psychiatric morbidity psoriasis and PsA, including suicidality outcomes, we aimed to investigate its relationship with disease characteristics psychopathology We surveyed 216 adults attending a specialist service, 83 whom had comorbid PsA. Participants completed paper questionnaires about...