- Advanced Radiotherapy Techniques
- Prostate Cancer Diagnosis and Treatment
- Glioma Diagnosis and Treatment
- Prostate Cancer Treatment and Research
- Brain Metastases and Treatment
- Colorectal Cancer Surgical Treatments
- Radiation Therapy and Dosimetry
- Medical Imaging Techniques and Applications
- Endometrial and Cervical Cancer Treatments
- Meningioma and schwannoma management
- Colorectal and Anal Carcinomas
- Management of metastatic bone disease
- Radiation Dose and Imaging
- Ovarian cancer diagnosis and treatment
- Colorectal Cancer Treatments and Studies
- Breast Cancer Treatment Studies
- Radiopharmaceutical Chemistry and Applications
- Advanced X-ray and CT Imaging
- MRI in cancer diagnosis
- Radiation Detection and Scintillator Technologies
- Advances in Oncology and Radiotherapy
- Sarcoma Diagnosis and Treatment
- Cervical Cancer and HPV Research
- Testicular diseases and treatments
- Advanced MRI Techniques and Applications
University of Rome Tor Vergata
2010-2021
Policlinico Tor Vergata
2011-2020
Osservatorio astronomico di Bologna
2016
University of Bologna
2016
Università Campus Bio-Medico
2016
Azienda Ospedaliero-Universitaria di Modena
2010-2016
Herlev Hospital
2016
University of Copenhagen
2016
Expert System (Italy)
2016
Istituto Oncologico Veneto
2010-2012
The aim of the present study is to evaluate impact metastases-directed stereotactic body radiotherapy in two groups oligometastatic prostate cancer (PC) patients: oligorecurrent PC and oligoprogressive castration-resistant (oligo-CRPC). Inclusion criteria multicentre retrospective analysis were: (1) PC, defined as presence 1–3 lesions (bone or nodes) detected with choline positron emission tomography CT plus bone scan following biochemical recurrence; (2) oligo-CRPC, metastases after a...
To identify predictive factors of radiation-induced skin toxicity in breast cancer patients by the analysis dosimetric and clinical factors.339 treated between January 2007 December 2010 are included present analysis. Whole irradiation was delivered with Conventional Fractionation (CF) (50 Gy, 2.0/day, 25 fractions) moderate Hypofractionated Schedule (HS) (44 2.75 Gy/day, 16 followed tumour bed boost. The impact patient features, systemic treatments and, particular, dose inhomogeneities on...
OBJECTIVE To investigate the pattern of care and outcomes for newly diagnosed glioblastoma in Italy compare our results with previous Italian Patterns Care study to determine whether significant changes occurred clinical practice during past 10 years. METHODS Clinical, pathological, therapeutic, survival data regarding 1059 patients treated 18 radiotherapy centers between 2002 2007 were collected retrospectively reviewed. RESULTS Most underwent both computed tomography magnetic resonance...
Purpose: To investigate the dosimetric properties of synthetic single crystal diamond based Schottky diodes under irradiation with therapeutic electron beams from linear accelerators. Methods: A detector was fabricated and tested 6, 8, 10, 12, 15 MeV beams. The performances were evaluated using three types commercial detectors as reference dosimeters: an Advanced Markus plane parallel ionization chamber, a Semiflex cylindrical ap-type silicon detector. Preirradiation, linearity dose, dose...
Background/Aim: This multicenter, retrospective, ‘field-practice’ study investigated treatment outcomes of ongoing abiraterone therapy with the addition radiotherapy (RT) – initiated for oligoprogression or a palliative intent. Patients and Methods: Consecutive patients affected by metastatic castration-resistant prostate cancer (mCRPC) treated acetate were considered if they had received RT after initiation treatment. Results: A total 32 enrolled in study. Median duration was 13.0 months...
OBJECTIVE To analyse relapse patterns, toxicity and second malignancy in patients with stage I pure germ cell testicular tumours, treated 1970–1999. PATIENTS AND METHODS In all, 487 received irradiation after surgery to the infra‐ (407, 83.5%) or supra‐diaphragmatic volumes (80, 16.5%). Treatment‐related was classified according previous criteria fertility investigated 246 men. Second malignancies were identified by retrospective analysis of clinical records telephone interviews men who no...
Although the evidence for benefit of adding temozolomide (TMZ) to radiotherapy (RT) is limited glioblastoma patients, there currently a trend toward treating anaplastic astrocytomas (AAs) with combined RT + TMZ. The aim present study was describe patterns care patients affected by AA and, particularly, compare outcome treated exclusively those Data 295 newly diagnosed AAs postoperative ± TMZ in period from 2002 2007 were reviewed. More than 75% underwent surgical removal. All had RT; 86.1%...
The aims of this study were to assess the clinical usefulness [Tc-99m] tetrofosmin (TF) single photon emission computed tomography (SPECT) and X-ray transmission (CT), performed simultaneously with a hybrid imaging device for functional anatomical mapping brain tumors evaluate additional information SPECT/CT when compared SPECT alone. Thirty (30) patients studied: 20 evaluated before undergoing surgery 10 after radiotherapy planning. acquisition both morphologic (CT) images obtained in...
To evaluate the outcome of patients affected by a single isolated body metastasis treated with stereotactic radiotherapy (SBRT).Seven-eight were SBRT for metastasis. The most frequent primary tumor was prostate cancer (28.2%), followed colorectal (23.1%) and lung (20.5%). Median age at diagnosis oligometastatic disease 70 years (range 47-88). Karnofsky Performance Status (KPS) 90 70-100). common fractionation scheme 5 × 7 Gy (total dose 35 Gy). Response to determined according RECIST...
High-energy electron beams generated by linear accelerators, typically in the range 6 to 20 MeV, are used small field sizes for radiotherapy of localized superficial tumors. Unshielded silicon diodes (Si-D) commonly considered suitable detectors relative dose measurements fields due their high spatial resolution. Recently, a novel synthetic single crystal diamond diode (SCDD) showed properties standard and photon dosimetry. The aim present study is twofold: characterize 15 MeV shaped using...
Abstract Background To assess interfraction translational and rotational setup errors, in patients treated with image-guded hypofractionated stereotactic radiotherapy, immobilized by a thermoplastic mask bite-block positioned using coordinates. Methods 37 47 brain metastases were stererotactic radiotherapy. All combination of fixed to frame support. Daily cone-beam CT scans acquired for every patient before the treatment session matched online planning images, 3D image registration. The mean...