- Rabbits: Nutrition, Reproduction, Health
- Animal Nutrition and Physiology
- Phytase and its Applications
- Insect Utilization and Effects
- Crop Yield and Soil Fertility
- Moringa oleifera research and applications
- Agriculture Sustainability and Environmental Impact
- Genetics and Plant Breeding
- Bone Tissue Engineering Materials
- Horticultural and Viticultural Research
- Neonatal Respiratory Health Research
- Nuts composition and effects
- Adipose Tissue and Metabolism
- Probiotics and Fermented Foods
- Plant Micronutrient Interactions and Effects
- Aquaculture Nutrition and Growth
- Food composition and properties
- Proteins in Food Systems
- Liver Disease Diagnosis and Treatment
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Architecture and Computational Design
- Liver physiology and pathology
- Corneal Surgery and Treatments
- GABA and Rice Research
- Dietary Effects on Health
University of Milan
2011-2024
Istituto Sperimentale per la Zootecnia
2007
Istituto di Biologia e Biotecnologia Agraria
2005
Consumption of legumes is associated with a number physiological and health benefits. Legume proteins complement very well those cereals are often used to produce gluten-free products. However, legume seeds contain antinutritional compounds, such as phytate, galactooligosaccharides, phenolic lectins, enzyme inhibitors, whose presence could affect their nutritional value. Screening natural induced biodiversity for useful traits, followed by breeding, way remove undesirable components. We the...
Abstract Growing evidence suggests a mechanistic link between inflammation and the development progression of fibrotic processes. Mesenchymal stromal cells derived from human amniotic membrane (hAMSCs), which display marked immunomodulatory properties, have been shown to reduce bleomycin-induced lung fibrosis in mice, possibly by creating microenvironment able limit evolution chronic fibrosis. However, ability hAMSCs modulate immune involved pulmonary has yet be elucidated. Herein, we...
Probiotic microorganisms may benefit the host by influencing diverse physiological processes, whose nature and underlying mechanisms are still largely unexplored. Animal models a unique tool to understand complexity of interactions between probiotic microorganisms, intestinal microbiota, host. In this regard, in pilot study, we compared effects 5-day administration three different bacterial strains ( Bifidobacterium bifidum MIMBb23sg, Lactobacillus helveticus MIMLh5, Lacticaseibacillus...
Abstract Myofibroblasts are key fibrogenic cells responsible for excessive extracellular matrix synthesis characterizing the fibrotic lesion. In liver fibrosis, myofibroblasts derive either from activation of hepatic stellate (HSC) and portal fibroblasts (PF), or that originate ductular epithelial undergoing epithelial–mesenchymal transition. Ductular can also indirectly promote myofibroblast generation by activating TGF‐β, main growth factor, through αvβ6 integrin. addition, after injury,...
A total of 18 hybrid strain Martini male rabbits were randomly divided into three experimental groups. The animals in the first and second groups drank water with 0.1 0.5 g/l lycopene addition (B C groups, respectively), while without any supplement was administered to control group (A group) for 8 weeks. Semen collected from bucks (6 animals/group) 5 consecutive Ejaculate volume determined by graduated test tube sperm concentration calculated Neubauer chamber. Sperm motility evaluated...
Monogastric animals are unable to digest phytic acid, so it represents an antinutritional factor and also environmental problem. One strategy solve this problem is the utilization of low acid (lpa) mutants that accumulate levels P high free phosphate in seeds; among lpa maize lpa1 exhibited highest reduction seed. This study indicated mutations exerted pleiotropic effects not directly connected pathway, such as on seed density, content ions, antioxidant compounds present kernels. Furthermore...
Abstract Aldehyde-oxidase-4 (AOX4) is one of the mouse aldehyde oxidase isoenzymes and its physiological function unknown. The major source AOX4 Harderian-gland, where enzyme characterized by daily rhythmic fluctuations. Deletion Aox4 gene causes perturbations in expression circadian-rhythms pathway, as indicated transcriptomic analysis. inactivation alters diurnal oscillations master clock-genes. Similar effects are observed other organs devoid AOX4, such white adipose tissue, liver...
Angelman syndrome (AS, MIM 105830) is a rare neurodevelopmental disorder affecting 1:10-20,000 children. Patients show moderate to severe intellectual disability, ataxia and absence of speech. Studies on both post-mortem AS human brains mouse models revealed dysfunctions in the extra synaptic gamma-aminobutyric acid (GABA) receptors implicated pathogenesis. Taurine free intracellular sulfur-containing amino acid, abundant brain, considered an inhibiting neurotransmitter with neuroprotective...
The current trial was carried out on a commercial poultry farm to study the effect of skim milk powder (SMP) added diet containing Lactobacillus acidophilus performance and egg quality laying hens from 20 49 wk age. A total 2,400 Hy-Line W-36 were housed in 600 unenriched cages (4 each) located over 4 tier levels. Animals assigned 1 3 experimental treatments (0, 3, 4). received enriched respectively with 4% SMP, whereas animals treatment 0 fed without SMP. All diets, moreover, supplemented...
Abstract This study investigated the potential of using organic fraction municipal solid waste (OFMSW) as a rearing substrate for black soldier fly larvae (BSF). Samples OFSMW were collected in Italy four different seasons year and fed untreated or pulped to larvae. The successfully grew on OFMSW with minimal impact from either season pretreatment (pulped vs untreated). Notably, all treatments achieved high larval survival rates (above 89.2%) development time within 11 days. Season...
Abstract Biomass represents an important source of renewable energy, and in most countries it is now considered essential for environmental policies to include sustainable energy production. The direct burning maize grains contaminated by mycotoxins house heating or harvested grain drying may represent interesting economically efficient way salvage otherwise unusable product. This work aims identify those seed traits correlated with the heat content, which can be helpful assessing...
To investigate the relationship between dietary nutrient concentration and weaning age on growth performance caecal characteristics of rabbits, a trial was carried out 64 litters (eight rabbits/litter) comparing two ages (25 vs. 34 d) diets (HC: high concentrated LC: low diet) offered to kits from 18 d age. At 54 animals per group were caged individually all fed LC diet until 45 All then standard fattening (37% neutral detergent fiber, 3.4% ether extract 18.0% crude protein dry matter basis)...
The aim of this study was to investigate the effect age and diet at weaning on growth performances, caecal characteristics development potential pathogenetic microflora. trial carried out 64 litters from 18 45 days comparing two (25 vs. 34 d) diets (HF LF) characterized, especially, by different energy, fat starch concentration (HF: DE=11.5 MJ/kg, EE=6.2%, Starch=8.7%; LF: DE=10.1 MJ/kg DM, EE=3.1%, Starch=11.3%).At d, early determined a significant reduction (1219 vs 1282; P<0.01), although...
Energy content of the diets is major factor that affect feed intake in poultry. Fats and oils are most concentrated sources energy, but also those from which availability and, therefore, metabolizable energy show greatest variation (Blanch et al., 1996). This influenced by several factors as saturated unsaturated fatty acids ratio (Vila 1996a, Castrovilli 1994) percentage free 1996b). Another source animal’s age:Wiseman Salvador (1989) reported an improvement utilisation dietary fats...
This study proposes the integration of an earthenware-based biofilter into photobioreactors, to allow Spirulina (Arthrospira platensis) growth using fully-organic nutrient sources. The earthenware membrane was efficiently selectively-permeable material, enabling oxidation soluble organics and diffusion mineralised ions photobioreactor, while retaining organic suspended solids indigenous heterotopic bacteria. Feeding lactic acid fermentation effluents (organic loading rates, reported per unit...