About
Contact & Profiles
A5116544257
Research Areas
- Viral Infections and Immunology Research
- Animal Virus Infections Studies
- Viral gastroenteritis research and epidemiology
Viruses have evolved elaborate mechanisms to hijack the host mRNA translation machinery direct viral protein synthesis. Picornaviruses, whose RNA genomes lack a cap structure, inhibit cap-dependent translation, and utilize an internal ribosome entry site (IRES) in 5′-UTR recruit 40S ribosomal subunit. IRES activity is stimulated by set of proteins termed trans-acting factors (ITAFs). The cellular ITAF 45 (also known as PA2G4 EBP1) was identified essential for foot-and-mouth disease virus...
10.1101/2025.03.05.641721
preprint
EN
cc-by-nd
bioRxiv (Cold Spring Harbor Laboratory)
2025-03-05
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