A5037149785- Traumatic Brain Injury and Neurovascular Disturbances
- Traumatic Brain Injury Research
- Glioma Diagnosis and Treatment
- Radiomics and Machine Learning in Medical Imaging
- Mitochondrial Function and Pathology
- PARP inhibition in cancer therapy
- Sirtuins and Resveratrol in Medicine
- S100 Proteins and Annexins
- MicroRNA in disease regulation
- Neurosurgical Procedures and Complications
- Spinal Fractures and Fixation Techniques
- Intracranial Aneurysms: Treatment and Complications
- Circular RNAs in diseases
- Acute Ischemic Stroke Management
- Pregnancy-related medical research
- Wound Healing and Treatments
- Cancer-related molecular mechanisms research
- Frailty in Older Adults
- Periodontal Regeneration and Treatments
- Cardiovascular Health and Disease Prevention
- Autophagy in Disease and Therapy
- Biomarkers in Disease Mechanisms
- Long-Term Effects of COVID-19
- Hemostasis and retained surgical items
- Esophageal and GI Pathology
Yangzhou University
2021-2024
Trinity College Dublin
2024
Dalian Medical University
2020-2022
Dalian University
2022
Northern Jiangsu People's Hospital
2021
Gut microbiota is associated with the growth of various tumors, including malignant gliomas, through brain-gut axis. Moreover, gut in patients tumors may considerably differ from those benign tumors. However, associations and brain remain unclear. Hence, order to explore these underlying relationships, meningioma (n = 32), glioma 27), healthy individuals 41) were selected participate this study. The results showed that diversity microbial ecosystem tumor less than controls, while no...
Glioma, one of the most prevalent malignant tumors, is well-known for its poor prognosis and low survival rate among patients. As a type non-coding RNA, circular RNAs (circRNAs) play significant role in tumor progression. However, function circRNAs glioma development remain unclarified. In our experiments, relative expression level circRNA_0067934 miR-7 tissue was detected by qRT-PCR, specific gene knockdown mediated siRNA miRNA-inhibitor. Dual-luciferase reporter assay carried out to...
Hair follicle regeneration has been successful in mice but failed human being for years. Dermal papilla cells, a specialized mesenchymal stem cell derived from dermal within hair follicles, is considered the key cells function as both initiator and regulator. Injectable platelet rich fibrin (i-PRF), novel biomaterial variety of growth factors three-dimensional scaffolds, shown promising effects on tissue regeneration. In this study, we aimed to evaluate application i-PRF by examining...
Purpose This study aimed to investigate the changes in functional connectivity between bilateral thalamus and whole-brain patients with severe traumatic brain injury (sTBI) suffering from disorders of consciousness (DOC) explore their potential prognostic representation capacity. Methods The sTBI DOC healthy controls underwent magnetic resonance imaging. We defined Extended Glasgow Outcome Score (GOS-E) ≥ 3 as wake group GOS-E = 2 coma group. differences groups were compared. Based on...
Abstract Temporal muscle thickness (TMT) serves as an indicator of sarcopenia and holds predictive value for various cancers. This study aims to evaluate the prognostic significance TMT high-grade glioma patients. A retrospective review 172 patients from January 2015 December 2022 was conducted. measured based on contrast-enhanced T1-weighted magnetic resonance images before surgery. Pearson analysis used potential correlations. Cox regression performed overall survival In our study, cutoff...
Many combinations of inflammation-based markers have been reported their prognostic ability. The value albumin-to-gama-glutamyltransferase ratio (AGR), an inflammation-related index, has identified for several cancers. However, the predictive AGR high-grade glioma patients remains unclear. As a result, this study was conducted to assess in (WHO III and IV) develop nomogram. Data from 185 diagnosed with gliomas, who underwent surgical treatment between March 2013 December 2022, were...
<title>Abstract</title> Background Nicotinamide (NAM) metabolism plays a significant role in glioma development. This study aimed to investigate the correlation between NAM metabolic genes and prognosis, immune microenvironment, tumor progression glioma. Methods We analyzed expression prognostic significance of NAM-metabolism-related patients with develop new metabolism-related signature (NMRS) nomograms using data from The Cancer Genome Atlas (TCGA) Gene Expression Omnibus (GEO) databases...
Background: Celastrol, a component of Tripterygium wilfordii Hook F, emerged potent anti-inflammatory and anti-oxidant properties, which has been proved as neuroprotective agent in variety central nervous system (CNS) diseases. However, its therapeutic potential intracerebral hemorrhage (ICH) remains elusive. The aim this research was to conduct an inquiry into the effects celastrol on ICH.Methods: Collagenase IV-induced ICH model performed male C57BL/6 mice administered through...
Traumatic brain injury (TBI) has emerged as an increasing public health problem but not been well studied, particularly the mechanisms of cellular behaviors during TBI. In this study, we established ischemia/reperfusion (I/R) mice model using transient middle cerebral artery occlusion (tMCAO) strategy. After then, RNA-sequencing frontal lobes was performed to screen key inducers To further verify selected genes, collected peripheral blood mononuclear cells (PBMCs) from TBI patients within 24...
Abstract Objective: The aim of present study was to evaluate the efficacy and safety fibrin sealant on knee function restoration following total replacement. Methods: PubMed, Web Science, Cohrane library, Embase were searched up August 2021. All prospective randomized controlled trial involving treatment for replacement included in this meta-analysis. Range motion, blood loss, transfusion rate, hemoglobulin reduction, hospital stay, complication calculated using RevMan 5.4 software.Results:...