A5062530802- Reproductive biology and impacts on aquatic species
- Fish Ecology and Management Studies
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Fish biology, ecology, and behavior
- Fish Biology and Ecology Studies
- Pharmacogenetics and Drug Metabolism
- Aquaculture Nutrition and Growth
- Birth, Development, and Health
- Sperm and Testicular Function
- Effects and risks of endocrine disrupting chemicals
- Environmental Toxicology and Ecotoxicology
- Neonatal Health and Biochemistry
- Neuroscience and Neuropharmacology Research
- Pancreatic function and diabetes
- Liver Disease Diagnosis and Treatment
- Sepsis Diagnosis and Treatment
- Drug Transport and Resistance Mechanisms
- Marine Biology and Environmental Chemistry
- Adipose Tissue and Metabolism
- Agricultural and Food Sciences
- Hearing, Cochlea, Tinnitus, Genetics
- Renal function and acid-base balance
- Nerve injury and regeneration
- Cannabis and Cannabinoid Research
- Effects of Environmental Stressors on Livestock
University of California, San Diego
2020-2024
Universidade Federal de Minas Gerais
2015-2022
Université Laval
2021
Shiga University of Medical Science
2021
Leibniz Institute for Neurobiology
2019-2020
Instituto Federal Catarinense
2018-2020
University Medical Center Groningen
2020
University of Groningen
2020
Hospital de Clínicas de Porto Alegre
2017
Pontifícia Universidade Católica de Minas Gerais
2011-2015
A total of 312 adults matrinxã were captured bimonthly, between 2011-2012, in two sites the rio São Francisco: immediately downstream Três Marias Dam (site 1) and confluence with Abaeté 2). Specimens Brycon orthotaenia from site 2 presented higher values length (32.24 ± 5.70 cm for females 26.64 3.79 males) body weight (506.66 332.17 g 267.36 145.84 males), when compared 1. In was registered highest GSI means (9.97 2.96 0.93 0.52 1 means. Reproduction period occurred October to February....
Abstract Here we show that Triclosan (TCS), a high-volume antimicrobial additive has been detected in human breastmilk, can be efficiently transferred by lactation to newborn mice, causing significant fatty liver (FL) during the suckling period. These findings are relevant since pediatric non-alcoholic disease (NAFLD) is escalating United States, with limited mechanistic understanding. Lactational delivery stimulated hepatosteatosis, triglyceride accumulation, endoplasmic reticulum (ER)...
Discharge of municipal wastewater promotes the entry diverse oestrogenic compounds into water bodies. This complex mixture substances interferes in steroidogenic pathway, being able to promote severe reproductive impairment freshwater fish populations. The purpose present study was evaluate effects endocrine disruptors (EDCs) on gonadal sex steroids (testosterone, T; 11-ketotestosterone, 11-KT; 17β-oestradiol, E2; 17-hydroxyprogesterone, 17-OHP) peak season Astyanax rivularis, correlating...
AB Aquatic Biology Contact the journal Twitter RSS Mailing List Subscribe to our mailing list via Mailchimp HomeLatest VolumeAbout JournalEditorsTheme Sections 19:195-200 (2013) - DOI: https://doi.org/10.3354/ab00531 NOTE Downstream impacts of a dam and influence tributary on reproductive success Leporinus reinhardti in São Francisco River André Alberto Weber1, Diego Mendes Ferreira Nunes1, Rafael Zeferino Gomes1, Elizete Rizzo2, Kléber Biana Santiago3, Nilo Bazzoli1,* 1Laboratório de...
Continental waters salinisation is a global threat that has grown because of climate change and human activities, but little known about how what biological tracts are affected. The aim this study was to investigate the influence different water salinities on expression HSP70, PCNA caspase-3 during spermatogenesis Nile tilapia. Adult males were submitted four salinity treatments: (S0) fresh water, (S7) 7 g L-1, (S14) 14 (S21) 21 L-1 for 1, 4, 9 days. All specimens in spermatogenic activity...
Abstract Neonatal hyperbilirubinemia or jaundice is associated with kernicterus, resulting in permanent neurological damage even death. Conventional phototherapy does not prevent eliminate the need for exchange transfusion. Here we investigated potential of therapeutic bile acids ursodeoxycholic acid (UDCA) and obeticholic (OCA, 6-α-ethyl-CDCA), a farnesoid-X-receptor (FXR) agonist, as preventive treatment options neonatal using hUGT1*1 humanized mice Ugt1a -deficient Gunn rats. Treatment...
Summary This study shows for the first time presence of a jelly coat on oocytes neotropical Characiformes fish. structure could be responsible adhesiveness Astyanax bimaculatus oocytes, species widely distributed in South America including São Francisco River basin Brazil. Adult specimens A. were submitted to artificial reproduction order analyse egg morphology and embryonic development. The eggs fertilised kept incubators with water temperature 24°C so that embryogenesis monitored. Ovulated...
To support sperm production, fish testes undergo intense tissue remodelling, with endocrine, paracrine and autocrine signals regulating gonad physiology. The aim of this study was to investigate the testicular expression insulin-like growth factor (Igf) 1 Igf2 during spermatogenesis, their relationship cell proliferation apoptosis throughout reproductive cycle. performed in male Hypostomus garmani, a catfish living headwater rivers São Francisco River basin, Brazil. Spermatogenesis analysed...
Background: Newborns can be exposed to inorganic arsenic (iAs) through contaminated drinking water, formula, and other infant foods. Epidemiological studies have demonstrated a positive association between urinary iAs levels the risk of developing nonalcoholic fatty liver disease (NAFLD) among U.S. adolescents adults. Objectives: The present study examined how oral administration neonatal mice impacts intestinal tract, which acts as an early mediator for NAFLD. Methods: Neonatal were treated...
Correct brain wiring depends on reliable synapse formation. Nevertheless, signaling codes promoting synaptogenesis are not fully understood. Here, we report a spinogenic mechanism that operates during neuronal development and is based the interaction of tumor necrosis factor receptor-associated 6 (TRAF6) with synaptic cell adhesion molecule neuroplastin. The between these proteins was predicted in silico verified by co-immunoprecipitation extracts from rat co-transfected HEK cells. Binding...
The sequence of changes in systemic and renal oxygen delivery (QO2) consumption (VO2) function an ovine model progressive hyperdynamic sepsis was investigated. Nine chronically instrumented awake sheep were given a continuous intravenous Escherichia coli endotoxin infusion (20 ng.kg-1.min-1) for 3 days. After 8 h the infusion, arterial blood pressure vascular resistance stayed decreased by 30% (P less than 0.001). Systemic QO2 progressively increased to maximum 157% baseline values at 24...
Bisphenol A (BPA) is an organic synthetic compound used in the plastic industry with endocrine disrupting activity. Although it frequently found surface waters, few studies have investigated its impact on fish gametogenesis, particularly when associated natural stressors. In this regard, present study evaluated BPA toxicity spermatogenesis lambari Astyanax bimaculatus under controlled conditions and interactive effects water temperature. Adult specimens were exposed duplicate to 40 μg/L 400...
UDP-glucuronosyltransferase (UGT) 1A1 is the only transferase capable of conjugating serum bilirubin. However, temporal delay in development UGT1A1 gene leads to an accumulation bilirubin newborn children. Neonatal humanized UGT1 (hUGT1) mice, which accumulate severe levels total (TSB), were treated by oral gavage with obeticholic acid (OCA), a potent FXR agonist. OCA treatment led dramatic reduction TSB levels. Analysis expression confirmed that induced intestinal and not hepatic UGT1A1....
The human UDP-glucuronosyltransferases (UGTs) represent an important family of drug-metabolizing enzymes, with UGT1A1 targeting the conjugation and detoxification many exogenous substances, including pharmaceutical drugs. In this study we generated humanized mice expressing <i>UGT1A1</i> gene in either liver (<i>hUGT1A1<sup>HEP</sup></i>) or intestine (<i>hUGT1A1<sup>GI</sup></i>), enabling experiments to examine tissue-specific properties UGT1A1-specific glucuronidation. Hepatic intestinal...
Food restriction is part of the life cycle many fish species; however, nutritional deficiency may negatively influence gametogenesis and gonadal maturation. The aim this study was to evaluate effects food on spermatogenesis Nile tilapia. For this, adult males were submitted starvation refeeding cycles (alternating periods feeding) for 7, 14, 21, 28 days. After 7 days starvation, glycaemic lipid levels significantly reduced, followed by reduction plasma testosterone (T) 11-ketotestosterone...
Summary This study presents, for the first time, information on eggs and early development of F ranciscodoras marmoratus , fish S ão rancisco river, B razil. To analyse egg ultrastructure morphological events embryogenesis, a total 36 . specimens (18 males 18 females) were captured subjected to spawning induction. Gametes collected by manual extrusion, fertilization was conducted using dry method. After fertilization, kept in incubators with water temperature 24° C The embryonic monitored...
This study isolated Alphitobius diaperinus (live and dead) insects from shed’s aviary bed to investigate their fungi spores distribution (that affects chicken health meat production) accumulation sites (dorsal & ventral) characteristics by different microscopies (stereo scanning electron). Despite live beetles being the main spore carriers, dead ones had far more attached on body exoskeleton thereby a focus of infection. That was due anatomical favoring trapping effect, together with...