Philippos Gourzis

ORCID: 0000-0003-2001-4584
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About
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Research Areas
  • Schizophrenia research and treatment
  • COVID-19 and Mental Health
  • Alzheimer's disease research and treatments
  • Dementia and Cognitive Impairment Research
  • Multiple Sclerosis Research Studies
  • Mental Health and Psychiatry
  • Health and Well-being Studies
  • Health disparities and outcomes
  • Tryptophan and brain disorders
  • Personality Disorders and Psychopathology
  • Neurological disorders and treatments
  • Treatment of Major Depression
  • Psychosomatic Disorders and Their Treatments
  • Bipolar Disorder and Treatment
  • Child and Adolescent Psychosocial and Emotional Development
  • Healthcare professionals’ stress and burnout
  • Obsessive-Compulsive Spectrum Disorders
  • Mental Health Research Topics
  • Parkinson's Disease Mechanisms and Treatments
  • Resilience and Mental Health
  • Nicotinic Acetylcholine Receptors Study
  • Mental Health Treatment and Access
  • Healthcare Decision-Making and Restraints
  • COVID-19 Pandemic Impacts
  • Aging and Gerontology Research

University of Patras
2016-2025

General University Hospital of Patras
2016-2025

Eginition Hospital
2024

National and Kapodistrian University of Athens
2024

Creative Research Enterprises (United States)
2018

University of Ioannina
2017

Sotiria General Hospital
2017

Pharmacogenomics (PGx) holds promise to revolutionize modern healthcare. Although there are several prospective clinical studies in oncology and cardiology, demonstrating a beneficial effect of PGx-guided treatment reducing adverse drug reactions, very few such psychiatry, none which spans across all main psychiatric indications, namely schizophrenia, major depressive disorder bipolar disorder. In this study we aim investigate the effectiveness (occurrence hospitalisations re-admissions,...

10.1016/j.ebiom.2024.105009 article EN cc-by-nc-nd EBioMedicine 2024-02-16

: The study aims to provide a comprehensive neuropsychological analysis of psychotic spectrum disorders, including schizophrenia, bipolar disorder, and depression. It focuses on the critical aspects cognitive impairments, diagnostic tools, intervention efficacy, roles genetic environmental factors in these disorders. paper emphasizes significance tests identifying deficiencies their predictive value early management psychosis.

10.3390/medicina60040645 article EN cc-by Medicina 2024-04-17

We conducted a randomized, open-label, controlled trial to assess the efficacy of oxcarbazepine for prophylaxis against oxaliplatin-induced peripheral neuropathy (OxIN). Thirty-two patients with colon cancer received 12 courses FOLFOX-4 regimen and were randomly assigned receive (600 mg BID) or chemotherapy without oxcarbazepine. The incidence OxIN was strikingly decreased in receiving (31.2% vs 75%). Oxcarbazepine may prevent symptoms. Further larger placebo-controlled trials are warranted...

10.1212/01.wnl.0000249344.99671.d4 article EN Neurology 2006-12-26

Aim. The current prospective study sought to trace the incidence and severity of oxaliplatin-induced peripheral neuropathy (OXLIPN) determine its clinical electrophysiological pattern. Patients methods. Twenty-five adult patients scheduled be treated with 12 courses oxaliplatin-based regimen, FOLFOX-4, for metastatic colon cancer participated in this study. were clinically electrophysiologically monitored at baseline followed-up during chemotherapy. OXLIPN was summarized by means a modified...

10.1080/02841860701355055 article EN Acta Oncologica 2007-01-01

Cognitive impairment is frequently encountered in multiple sclerosis (MS) affecting between 40–65% of individuals, irrespective disease duration and severity physical disability. In the present multicenter randomized controlled trial, fifty-eight clinically stable RRMS patients with mild to moderate cognitive relatively low disability status were receive either computer-assisted (RehaCom) functional training an emphasis on episodic memory, information processing speed/attention, executive...

10.1155/2017/5919841 article EN cc-by Behavioural Neurology 2017-01-01

The initial prodromal symptoms in schizophrenia were studied 100 DSM-diagnosed patients and controls. median number of the controls was 8 (range 2–13) 0 0–5), respectively. Patients developed indicating social, occupational, affective dysfunction, whereas controls' included magical content disturbance mood. There significant differences frequency several appearing subtypes. Initial classified into negative, positive-prepsychotic, positive-disorganization categories. with disorganized subtype...

10.1093/oxfordjournals.schbul.a006950 article EN Schizophrenia Bulletin 2002-01-01

The diagnostic accuracy of the German version revised Addenbrooke's Cognitive Examination (ACE-R) in identifying mild cognitive impairment (MCI), dementia Alzheimer's disease (AD) and frontotemporal lobar degeneration (FTLD) comparison with conventional Mini Mental State (MMSE) was assessed.The study encompasses 76 cognitively healthy elderly individuals, 75 patients MCI, 56 AD 22 FTLD. ACE-R MMSE were validated against an expert diagnosis based on a comprehensive procedure. Statistical...

10.1159/000312685 article EN Dementia and Geriatric Cognitive Disorders 2010-01-01

Background SARS-CoV-2 has rapidly spread worldwide, threatening public health and financial social life. Aims The current study's aim was to determine the prevalence of psychological distress post-traumatic stress symptoms in Greek population during first COVID-19 lockdown, detect potential correlates. Method An anonymous online survey conducted between 10 April 4 May 2020, collect information regarding people's functioning COVID-19-related perceptions. Results A total 1443 individuals...

10.1192/bjo.2021.17 article EN cc-by-nc-nd BJPsych Open 2021-02-24

The authors retrospectively reviewed all neurologic records of an emergency unit from 1999 to 2003 identify a potential association between lunar phases and seizure occurrence. Overall 859 patients admitted for occurrence were divided into the four quarters synodic month according moon phases. A significant clustering seizures around full period was observed, supporting ancient belief periodic increased frequency during full-moon days.

10.1212/01.wnl.0000210482.75864.e8 article EN Neurology 2006-05-09

Fluoxetine, a commonly prescribed medication for depression, has been studied in Alzheimer's disease (AD) patients its effectiveness on cognitive symptoms. The aim of this systematic review is to investigate the therapeutic potential fluoxetine decline AD, focusing anti-degenerative mechanisms action and clinical implications. According PRISMA, we searched MEDLINE, up 1 April 2024, animal human studies examining efficacy with regard recovery function AD. Methodological quality was evaluated...

10.3390/ijms25126542 article EN International Journal of Molecular Sciences 2024-06-13

Background Improving quality of life (QoL), is an important factor for patients diagnosed with non-melanoma cell cancer (NMSC). NMSC the most common and widespread in European population. Methods To measure QoL, several tools have been created, which try to capture evaluate it both before after treatment. The factors that contribute evaluation degree impact on patients' QoL are numerous sometimes overlap or interact each other. In present study, questionnaire used was General Health...

10.7759/cureus.77195 article EN Cureus 2025-01-09

Depression is the primary cause of psychological distress, particularly in a crisis like SARS-CoV-2 pandemic. Primary healthcare structures don't seem to be able identify and treat sizable percentage depressed individuals. This study aimed examine prevalence undiagnosed depression settings during post-COVID-19 pandemic its correlation with demographics alcoholism. cross-sectional used PHQ-9 (Patient Health Questionnaire-9) measure levels FAST (Fast Alcohol Screening Test) assess A total 212...

10.59429/esp.v9i12.3017 article EN Environment and Social Psychology 2025-01-20

Objective: The objective of this study was to estimate the prevalence and probable under-diagnosis depressive symptoms in elderly an urban semi-urban area Greece. Materials Methods: A cross-sectional conducted among members 4 days care centers for older people (KAPI), three municipality Patras, West-Greece, one Tripolis, Peloponnese, total 378 individuals took part study, aged >60 years. questionnaire developed collect basic demographic data, including questions from European Health...

10.4103/0019-5545.166617 article EN cc-by-nc-sa Indian Journal of Psychiatry 2015-01-01

This study estimated the crude prevalence of autism spectrum disorders (ASD) in Greece 2021. A retrospective was conducted for 2021 using data provided research purposes first time by Greek National Health Service Organization Healthcare Services Provision (EOPYY) related to ICD-10 diagnosis codes F84.0-F84.9 (ASD). Treatments were categorized gender, age, and location. Statistical analysis performed open-source software R. In total, 15,706 children aged 2-17 years registered with ASD:...

10.3390/jcm12072510 article EN Journal of Clinical Medicine 2023-03-27
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