A5067768038- Respiratory Support and Mechanisms
- Sepsis Diagnosis and Treatment
- Cardiac Arrest and Resuscitation
- Obstructive Sleep Apnea Research
- Intensive Care Unit Cognitive Disorders
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Tracheal and airway disorders
- Neonatal Respiratory Health Research
- Pleural and Pulmonary Diseases
- Neuroscience of respiration and sleep
- Nosocomial Infections in ICU
- Traumatic Brain Injury and Neurovascular Disturbances
- Pneumonia and Respiratory Infections
- Cardiac, Anesthesia and Surgical Outcomes
- Voice and Speech Disorders
- Sleep and related disorders
- Inhalation and Respiratory Drug Delivery
- Long-Term Effects of COVID-19
- Disaster Response and Management
- Family and Patient Care in Intensive Care Units
- Hemodynamic Monitoring and Therapy
- Respiratory and Cough-Related Research
- Tuberculosis Research and Epidemiology
- Airway Management and Intubation Techniques
- Thermal Regulation in Medicine
Mayo Clinic in Florida
2015-2024
WinnMed
2013-2024
Jacksonville College
2013-2022
Pulmonary Associates
2021
Triemli Hospital
2020
Stanford University
2012-2020
Southern Illinois University School of Medicine
2020
SleepMed
2019
Mayo Clinic
2003-2017
University of Michigan
2014-2015
Although ventilation with small tidal volumes is recommended in patients established acute lung injury, most others receive highly variable volume aimed part at normalizing arterial blood gas values. We tested the hypothesis that which develops after initiation of mechanical ventilation, associated known risk factors for ventilator-induced injury such as large volume.Retrospective cohort study.Four intensive care units a tertiary referral center.Patients who received invasive > or = 48 hrs...
Accurate, early identification of patients at risk for developing acute lung injury (ALI) provides the opportunity to test and implement secondary prevention strategies.To determine frequency outcome ALI development in validate a prediction score (LIPS).In this prospective multicenter observational cohort study, predisposing conditions modifiers predictive were identified from routine clinical data available during initial evaluation. The discrimination model was assessed with area under...
<h3>Importance</h3> Management of acute respiratory distress syndrome (ARDS) remains largely supportive. Whether early intervention can prevent development ARDS unclear. <h3>Objective</h3> To evaluate the efficacy and safety aspirin administration for prevention ARDS. <h3>Design, Setting, Participants</h3> A multicenter, double-blind, placebo-controlled, randomized clinical trial conducted at 16 US academic hospitals. Between January 2, 2012, November 17, 2014, 7673 patients risk (Lung...
Abstract Background: Acute respiratory distress syndrome (ARDS) remains a serious postoperative complication. Although ARDS prevention is priority, the inability to identify patients at risk for barrier progress. The authors tested and refined previously reported surgical lung injury prediction (SLIP) model in multicenter cohort of at-risk patients. Methods: This secondary analysis multicenter, prospective investigation evaluating high-risk undergoing surgery. Preoperative factors modifiers...
Objectives: Effective pharmacologic treatments directly targeting lung injury in patients with the acute respiratory distress syndrome are lacking. Early treatment inhaled corticosteroids and beta agonists may reduce progression to by reducing inflammation enhancing alveolar fluid clearance. Design: Double-blind, randomized clinical trial (ClinicalTrials.gov: NCT01783821). The primary outcome was longitudinal change oxygen saturation divided F io 2 (S/F) through day 5. We also analyzed...
Oxygen saturation to fraction of inspired oxygen ratio (SpO(2)/FiO(2)) has been validated as a surrogate marker for partial pressure among mechanically ventilated patients with acute respiratory distress syndrome (ARDS). The validity SpO(2)/FiO(2) measurements in predicting ARDS not studied. Recently, Lung Injury Prediction Score (LIPS) developed help identify at risk developing ARDS.This was secondary analysis the LIPS-1 cohort. A multivariate logistic regression included all established...
Limited critical care subspecialty training and experience is available in many low- middle-income countries, creating barriers to the delivery of evidence-based care. We hypothesized that a structured tele-education program using case-based learning ICU management principles an efficient method for knowledge translation quality improvement this setting. Weekly 45-min rounds were conducted recently established medical intensive unit (MICU) Banja Luka, Bosnia Herzegovina. The Checklist Early...
Context: The delivery of end-of-life care (EOLC) in the intensive unit (ICU) varies widely among medical providers. differing opinions nurses and physicians regarding EOLC may help identify areas improvement. Objective: To explore differences on ICU how these vary according to self-reported proficiency level primary work unit. Design: Cross-sectional survey 69 629 nurses. Setting: Single tertiary academic institution. Results: A total 50 (72%) 331 (53%) participated survey. Significant...
To evaluate clinical recognition of sleep apnea and related outcomes in patients hospitalized with acute ischemic stroke.A retrospective study all stroke from April 2008 to December 2014. The primary predictor outcome variables were hospital mortality, respectively. Secondary mechanical ventilation, length stay, the survivor's functional level by modified Rankin scale. A sensitivity multivariate regression analysis included propensity score for cardiovascular comorbidities apnea.Of 989...
We assessed the potential of risk stratification ARDS patients using SpO2/FiO2 and positive end-expiratory pressure (PEEP) at onset after 24 h. used data from a prospective observational study in admitted to mixed medical–surgical intensive care unit university hospital Netherlands. Risk was by cutoffs for PEEP. The primary outcome in-hospital mortality. Patients with moderate or severe length stay > h were included this study. assigned four predefined groups: group I (SpO2/FiO2 ≥ 190 PEEP <...
In this chapter we discuss recommendations on the identification of patients with acute respiratory distress syndrome (ARDS), indications for mechanical ventilation, and strategies lung-protective ventilation in resource-limited settings. Where blood gas analyzers are unavailable, it can be replaced by plethysmographic oxygen saturation/fractional inspirational concentration (SpO2/FiO2) gradient. Bedside lung ultrasound is a valuable diagnostic tool assessing pulmonary edema other...
The Surviving Sepsis Campaign guidelines are designed to decrease mortality through consistent application of a 7-element bundle. This study evaluated the impact improvement in bundle adherence using time-series analysis compliance with elements before and after interventions intended improve process, while also looking at hospital mortality. article describes used patients admitted emergency department sepsis, severe or septic shock. Quality methodology was develop high-impact that led...