Simin Dashti‐Khavidaki

ORCID: 0000-0003-2004-7845
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About
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Research Areas
  • Renal Transplantation Outcomes and Treatments
  • Pharmacological Effects and Toxicity Studies
  • Dialysis and Renal Disease Management
  • Organ Transplantation Techniques and Outcomes
  • Antibiotics Pharmacokinetics and Efficacy
  • Drug-Induced Hepatotoxicity and Protection
  • Antimicrobial Resistance in Staphylococcus
  • Metabolism and Genetic Disorders
  • HIV/AIDS drug development and treatment
  • Pharmaceutical Practices and Patient Outcomes
  • Chemotherapy-induced organ toxicity mitigation
  • Hepatitis C virus research
  • Bacterial Identification and Susceptibility Testing
  • Blood disorders and treatments
  • Pneumonia and Respiratory Infections
  • Pregnancy and Medication Impact
  • Acute Kidney Injury Research
  • Liver Disease and Transplantation
  • Antibiotic Use and Resistance
  • Bipolar Disorder and Treatment
  • Tryptophan and brain disorders
  • Silymarin and Mushroom Poisoning
  • Antibiotic Resistance in Bacteria
  • Liver Disease Diagnosis and Treatment
  • COVID-19 Clinical Research Studies

Tehran University of Medical Sciences
2016-2025

Imam Khomeini Hospital
2010-2021

AT Sciences (United States)
2021

Iran University of Medical Sciences
2015

Shahid Beheshti University of Medical Sciences
2014

Weatherford College
2012

University of Tehran
2008

Roozbeh Hospital
2004-2005

Purpose Healthcare workers have a main role in detection, assessment and spontaneous reporting of adverse drug reactions (ADRs), improvement their related knowledge, attitude perception is essential. The goal this study was evaluation clinical pharmacists' interventions healthcare about ADRs teaching referral hospital, Tehran, Iran. Method Changes Imam hospital were evaluated before after including workshops, meetings presentations. Results From the 100 participated subjects, 82 them...

10.1136/bmjopen-2011-000367 article EN cc-by-nc BMJ Open 2012-01-01

Despite several introduced preventive modalities, cisplatin nephrotoxicity remains a clinical problem. Some in vitro and vivo studies have addressed the protective effects of silymarin against nephrotoxicity. This study evaluated administration on as first human study. During this pilot, randomized, double‐blinded, placebo‐controlled trial, effect oral 420 mg daily three divided doses starting 24–48 h before initiation infusion continuing to end 21‐day cisplatin‐containing chemotherapy...

10.1002/ptr.5345 article EN Phytotherapy Research 2015-04-07

No effective antiviral drugs and vaccines are available for the treatment of patients with severe coronavirus 2019 (COVID-19). Therefore, available, safe, inexpensive supplements such as melatonin among proposed options controlling inflammation. We did a randomized, single-blind study in Imam Khomeini Hospital between June 30, 2020, August 5, 2020. Mild to moderate COVID-19 aged 25-65 years were eligible enter based on chest CT scan, clinical symptoms, physician diagnosis. The intervention...

10.18502/ijaai.v20i4.6959 article EN cc-by-nc Iranian Journal of Allergy Asthma and Immunology 2021-08-11

Herbal medications are being progressively utilized all over the world. Nevertheless, herbal remedies not without hazards and several cases of adverse reactions have been described. Tribulusterrestris is traditionally used because its aphrodisiac antiurolithiatic activities with almost complete inhibition stone formation. We report a case T. terrestris-induced hepatotoxicity, nephrotoxicity neurotoxicity in an Iranian male patient who plant's extract to prevent kidney He presented seizure...

10.1093/ndt/gfq457 article EN Nephrology Dialysis Transplantation 2010-07-28

This study was designed to compare the effects of fluoxetine and imipramine on fasting blood glucose (FBG) in patients with major depressive disorder. Sixty nondiabetic disorder (based Diagnostic Statistical Manual Mental Disorders, Fourth Edition criteria) entered this randomized, double-blind study. Patients did not receive any medication affecting serum FBG levels for at least 2 weeks before initiation were assigned 20 40 mg/d or 75 200 8 weeks. Pregnant women diabetes mellitus a history...

10.1097/01.jcp.0000132441.27854.0d article EN Journal of Clinical Psychopharmacology 2004-07-01

Human immunodeficiency virus infected individuals are prone to malnutrition due increased energy requirements, enteropathy and catabolism. Trace elements such as zinc selenium have major role in maintaining a healthy immune system. This study was designed evaluate the nutritional status of Iranian subjects who were newly diagnosed with human infection compare serum level these patients those sex aged match subjects. After an interview physical examination, assessment done based on clinical...

10.1186/1471-2334-8-165 article EN cc-by BMC Infectious Diseases 2008-12-01

Depression represents the most frequent psychiatric disorder in patients on maintenance haemodialysis (HD), and it might be associated with secretion of inflammatory cytokines. In this study, we explore possible correlations between depression pro-inflammatory (IL-1β, IL-6, TNF-α), anti-inflammatory (IL-10) cytokines, as well high-sensitivity C-reactive protein (hs-CRP) serum levels. Eighty three HD were enrolled cross-sectional study. Depressive symptoms measured Beck Inventory (BDI),...

10.1684/ecn.2013.0326 article EN European Cytokine Network 2012-10-01

Stress ulcers are acute superficial inflammatory lesions of the gastric mucosa induced when an individual is subjected to unusually high physiologic demands. In recent years, use acid suppression therapy (AST) for stress ulcer prophylaxis (SUP) in inpatient settings other than intensive care has become increasingly common, leading increased drug cost and avoidable risk adverse events such as hospitalacquired pneumonia.To assess effects a clinical pharmacist intervention including AST...

10.18553/jmcp.2010.16.2.114 article EN Journal of Managed Care Pharmacy 2010-03-01
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